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66 Cards in this Set

  • Front
  • Back
Congentin generic name
Benztropine
Congentin/Benztropine indications
Parkinsons disease
Congentin/Benztropine drug interactions
May decrease effects of phenothiazines and haloperidol
Congentin/Benztropine drug class and mechanism
Anti Parkinson's agent
anti cholinergic drug
Binds muscarinic receptors
Congentin/Benztropine side effects
dry mouth
Blurred vision
anti cholenergic effects
Sinemet generic name
Sinemet CR
Carbidopa with levodopa
Sinemet/Carbidopa w/ levodopa indications
Idiopathic Parkinson's disease
Postencephalitic parkinsonism
Symtomatic parkinsonism
Sinemet/Carbidopa w/ levodopa drug class
Anti Parkinsons agent
Sinemet/Carbidopa w/ levodopa drug intercactions
Avoid MAOIs
Hydantions and Vit B6 may decrease effectiveness
Individualized therapy reqd
Sinemet/Carbidopa w/ levodopa side effects
May cause dystonic or involuntary movements
Mirapex generic name
Pramipexole
Mirapex/Pramipexole indications
Idiopathic Parkinson's disease
Restless leg syndrome
Mirapex/Pramipexole drug interactions
Cimetidine decreases elimination
Mirapex/Pramipexole side effect
orthostatic hypotension
Hallucinations may occur during therapy
Mirapex/Pramipexole drug class and mechanism
Anti-Parkinson's agent
Dopamine agonist
Requip generic name
Requip XL
Ropinrole
Requip/Ropinrole
indications
Treats signs and symptoms of Idiopathic Parkinson's disease
Treats moderate to severe primary Restless leg syndrome
Requip/Ropinrole drug interactions
Smoking decreases AUC
Omeprazole decreases plasma levels
Ciprofloxin increases AUC
Requip/Ropinrole drug class and mechanism
Anti Parkinson's agent
Dopamine agonist
Requip/Ropinrole side effects
Hallucinations
Nausea
Drowsiness
Provigil generic name
Modafinil
Provigil/Modafinil indications
Narcolepsy
Obstructive sleep apnea/hypernoea syndrome (OSAHS)
Provigil/Modafinil drug interactions
May increase levels of diazepam and pheytoin
Provigil/Modafinil drug class and CS
pseudosympathomimetic

CS IV
Byetta generic name
Exenatide
Byetta/Exenatide indications
For adjunctive therapy to improve glycemic control in patients with type II diabetes
Byetta/Exenatide is used in combination with what other drugs?
Metformin, sulfonylureas and thiazolidinediones
Byetta/Exenatide drug intereactions
Drugs that require rapid GI absorption should be taken 30 min beforehand
Byetta/Exenatide diabetic advice/facts
Is not a substitute for insulin
Not for use with type 1 diabetes
Byetta/Exenatide counseling
Take within 60 min before a meal
BG and HbA1c monitoring reqd
Refrigerate syringes
Byetta/Exenatide drug class
Anti diabetic
Incretin mimetic
Amaryl generic name
Glimepiride
Amaryl/Glimepiride indications
For Tx of non-insulin dependent type II diabetes with hyperglycemia
Amaryl/Glimepiride drug interactions
Caution with drugs effecting CYP2c9
Amaryl/Glimepiride meal instructions
Take with first meal and watch for hypoglycemia
Amaryl/Glimepiride drug class and chemical class
Anti diabetic
sulfonylurea
Glucotrol generic name
Glucotrol XL
Glipizide
Glucotrol/Glipizide indications
Used to treat non-insulin dependent diabetes mellitus
Glucotrol/Glipizide drug interactions
Contraindicated with MAOI and chloramphenicol
Not for patients with sulfa allergies or history of diabetic ketoacidosis
Glucotrol/Glipizide side effects
Nausea, heartburn
mild hypoglcemia
Glucotrol/Glipizide drug class and chemical class
Anti diabetic
sulfonylurea
Glucotrol/Glipizide dose
Glucotrol: MDD 40mg/day
Glucotrol XL: MDD 20mg/day
Micronase generic name
Diabeta
Glyburide
Micronase and Diabeta/ Glyburide indications
Treatment of non-insulin dependent diabetes mellitus
Micronase and Diabeta/ Glyburide drug interactions
No MAOIs or chloramphenicol
Micronase and Diabeta/ Glyburide side effects
nausea, heartburn
mild hypoglcemia
Micronase and Diabeta/ Glyburide dose

Glynase (low dose brand) dose
Micronase/Diabeta:
MDD 20mg/day

Glynase: MDD 12mg/day
Micronase and Diabeta/ Glyburide drug class and chemical class
Anti diabetic
sulfonylurea
Glucophage generic name
Glucovance generic name
Metformin
Metformin with Glyburide
Glucophage/Metformin
indications
Tx of non-insulin dependent type II diabetes
Glucophage/Metformin
clinical warning
not forpatients with impaired renal or hapatic function
Glucophage/Metformin
warning
risk of lactic acidosis
Take with meals
Glucophage/Metformin
drug class
anti diabetic
Sinemet action
Levadopa crosses BBB and is converted into DA. Stimulates dopamine receptors. Elevates DA levels in brain
Carbidopa prevents DA degradation in periphery by inhibitong DA carboxylate
Miraex/Requip structure
similar to dopamine
Modafinil drug interaction
Can interfere with estrogen based contraceptives
Incretin mimetic action
Helps body release insulin
Slows GI transport of sugar and meds too
Sulfonylurea actions
Induces pancreas to pump out more insulin
Sulfonylurea drugs
Amaryl
Glucotrol
Micronase
Meal schedule for
Amaryl, Glyburide, Glipizide
Amaryl take with 1st meal
Glyburide take with first meal
Glipizide take 30 min prior to 1st meal
Micronized form of Glyburide
Glynase-absorbed faster/better therefore a lower dose is possible
Glucophage/Metformin action
1. increases sensitivity of insulin receptors
2. Cuts down on liver's production of glucose
3. lowers intestinal absorption of glucose
Does not work like sulfonylureas
Metformin and Metformin XR MDD
2500mg/day
2000 mg/day for XR
Byetta action
Incretin mimetic
Increases GLP1 path to increase insulin pumped out
Not a sulfonylurea path
Anti Parkinsons agents
Congentin/Benztropine
Sinemet/Carbidopa+levodopa
Mirapex/Pramipexole
Requip/Ropinrole
Incretin mimetic
Byetta/Exenatide