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66 Cards in this Set
- Front
- Back
Congentin generic name
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Benztropine
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Congentin/Benztropine indications
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Parkinsons disease
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Congentin/Benztropine drug interactions
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May decrease effects of phenothiazines and haloperidol
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Congentin/Benztropine drug class and mechanism
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Anti Parkinson's agent
anti cholinergic drug Binds muscarinic receptors |
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Congentin/Benztropine side effects
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dry mouth
Blurred vision anti cholenergic effects |
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Sinemet generic name
Sinemet CR |
Carbidopa with levodopa
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Sinemet/Carbidopa w/ levodopa indications
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Idiopathic Parkinson's disease
Postencephalitic parkinsonism Symtomatic parkinsonism |
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Sinemet/Carbidopa w/ levodopa drug class
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Anti Parkinsons agent
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Sinemet/Carbidopa w/ levodopa drug intercactions
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Avoid MAOIs
Hydantions and Vit B6 may decrease effectiveness Individualized therapy reqd |
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Sinemet/Carbidopa w/ levodopa side effects
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May cause dystonic or involuntary movements
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Mirapex generic name
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Pramipexole
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Mirapex/Pramipexole indications
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Idiopathic Parkinson's disease
Restless leg syndrome |
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Mirapex/Pramipexole drug interactions
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Cimetidine decreases elimination
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Mirapex/Pramipexole side effect
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orthostatic hypotension
Hallucinations may occur during therapy |
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Mirapex/Pramipexole drug class and mechanism
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Anti-Parkinson's agent
Dopamine agonist |
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Requip generic name
Requip XL |
Ropinrole
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Requip/Ropinrole
indications |
Treats signs and symptoms of Idiopathic Parkinson's disease
Treats moderate to severe primary Restless leg syndrome |
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Requip/Ropinrole drug interactions
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Smoking decreases AUC
Omeprazole decreases plasma levels Ciprofloxin increases AUC |
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Requip/Ropinrole drug class and mechanism
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Anti Parkinson's agent
Dopamine agonist |
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Requip/Ropinrole side effects
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Hallucinations
Nausea Drowsiness |
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Provigil generic name
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Modafinil
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Provigil/Modafinil indications
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Narcolepsy
Obstructive sleep apnea/hypernoea syndrome (OSAHS) |
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Provigil/Modafinil drug interactions
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May increase levels of diazepam and pheytoin
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Provigil/Modafinil drug class and CS
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pseudosympathomimetic
CS IV |
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Byetta generic name
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Exenatide
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Byetta/Exenatide indications
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For adjunctive therapy to improve glycemic control in patients with type II diabetes
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Byetta/Exenatide is used in combination with what other drugs?
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Metformin, sulfonylureas and thiazolidinediones
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Byetta/Exenatide drug intereactions
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Drugs that require rapid GI absorption should be taken 30 min beforehand
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Byetta/Exenatide diabetic advice/facts
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Is not a substitute for insulin
Not for use with type 1 diabetes |
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Byetta/Exenatide counseling
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Take within 60 min before a meal
BG and HbA1c monitoring reqd Refrigerate syringes |
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Byetta/Exenatide drug class
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Anti diabetic
Incretin mimetic |
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Amaryl generic name
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Glimepiride
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Amaryl/Glimepiride indications
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For Tx of non-insulin dependent type II diabetes with hyperglycemia
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Amaryl/Glimepiride drug interactions
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Caution with drugs effecting CYP2c9
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Amaryl/Glimepiride meal instructions
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Take with first meal and watch for hypoglycemia
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Amaryl/Glimepiride drug class and chemical class
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Anti diabetic
sulfonylurea |
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Glucotrol generic name
Glucotrol XL |
Glipizide
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Glucotrol/Glipizide indications
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Used to treat non-insulin dependent diabetes mellitus
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Glucotrol/Glipizide drug interactions
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Contraindicated with MAOI and chloramphenicol
Not for patients with sulfa allergies or history of diabetic ketoacidosis |
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Glucotrol/Glipizide side effects
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Nausea, heartburn
mild hypoglcemia |
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Glucotrol/Glipizide drug class and chemical class
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Anti diabetic
sulfonylurea |
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Glucotrol/Glipizide dose
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Glucotrol: MDD 40mg/day
Glucotrol XL: MDD 20mg/day |
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Micronase generic name
Diabeta |
Glyburide
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Micronase and Diabeta/ Glyburide indications
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Treatment of non-insulin dependent diabetes mellitus
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Micronase and Diabeta/ Glyburide drug interactions
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No MAOIs or chloramphenicol
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Micronase and Diabeta/ Glyburide side effects
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nausea, heartburn
mild hypoglcemia |
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Micronase and Diabeta/ Glyburide dose
Glynase (low dose brand) dose |
Micronase/Diabeta:
MDD 20mg/day Glynase: MDD 12mg/day |
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Micronase and Diabeta/ Glyburide drug class and chemical class
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Anti diabetic
sulfonylurea |
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Glucophage generic name
Glucovance generic name |
Metformin
Metformin with Glyburide |
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Glucophage/Metformin
indications |
Tx of non-insulin dependent type II diabetes
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Glucophage/Metformin
clinical warning |
not forpatients with impaired renal or hapatic function
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Glucophage/Metformin
warning |
risk of lactic acidosis
Take with meals |
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Glucophage/Metformin
drug class |
anti diabetic
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Sinemet action
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Levadopa crosses BBB and is converted into DA. Stimulates dopamine receptors. Elevates DA levels in brain
Carbidopa prevents DA degradation in periphery by inhibitong DA carboxylate |
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Miraex/Requip structure
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similar to dopamine
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Modafinil drug interaction
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Can interfere with estrogen based contraceptives
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Incretin mimetic action
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Helps body release insulin
Slows GI transport of sugar and meds too |
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Sulfonylurea actions
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Induces pancreas to pump out more insulin
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Sulfonylurea drugs
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Amaryl
Glucotrol Micronase |
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Meal schedule for
Amaryl, Glyburide, Glipizide |
Amaryl take with 1st meal
Glyburide take with first meal Glipizide take 30 min prior to 1st meal |
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Micronized form of Glyburide
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Glynase-absorbed faster/better therefore a lower dose is possible
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Glucophage/Metformin action
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1. increases sensitivity of insulin receptors
2. Cuts down on liver's production of glucose 3. lowers intestinal absorption of glucose Does not work like sulfonylureas |
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Metformin and Metformin XR MDD
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2500mg/day
2000 mg/day for XR |
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Byetta action
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Incretin mimetic
Increases GLP1 path to increase insulin pumped out Not a sulfonylurea path |
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Anti Parkinsons agents
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Congentin/Benztropine
Sinemet/Carbidopa+levodopa Mirapex/Pramipexole Requip/Ropinrole |
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Incretin mimetic
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Byetta/Exenatide
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