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52 Cards in this Set
- Front
- Back
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Zocor generic name
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Simvastatin
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Zocor/
Simvastatin drug class |
Statin
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Lipitor generic name
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Atorvastatin
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Lipitor/
Atorvastatin drug class |
Statin
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Zetia generic name
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Ezetimibe
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Zetia/
Ezetimibe drug class |
Cholesterol absorption inhibitor
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Vytorin generic name
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Ezetimibe with Simvastatin
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Tricor generic name
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Fenofibrate
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Tricor/
Fenofibrate drug class |
Fibrate
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Vytorin/
Ezetimibe with Simvastatin drug class |
Statin plus Cholesterol absorption inhibitor
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Lopid generic name
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Gemfibrozil
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Lopid/
Gemfibrozil drug class |
Fibrate
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Mevacor generic name
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Lovastatin (10, 20, 40 mg)
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Mevacor/
Lovastatin drug class |
statin
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Niaspan generic name
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Niacin extended release
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Lovaza generic name
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Omega-3-Acid ethyl ester
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Lovaza/
Omega-3-Acid ethyl ester drug class |
Antihyperlipidemic
(Omega-3 fatty acid) |
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Pravachol generic name
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Pravastatin
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Pravachol/
Pravastatin drug class |
Statin
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Pravachol/
Pravastatin dosage |
10-20 mg/day; adjust dosage at 4 week intervals until at a maximum of 40mg/day
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Crestor generic name
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Rosuvastatin
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Crestor/
Rouvastatin drug class |
Statin
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Statins are also called?
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HMG-CoA reductase inhibitors
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Fibrates perform what function?
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Lower triglyceride levels
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Statin warnings
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May increase Digoxin levels
Taking with Gemfibrozil can cause myopathy or rhabdomyolysis Grapefruit juice raise drug levels in blood plasma Myopathy (muscle pain) Avoid excessive alcohol Avoid excessive sunlight |
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Zocor/Simvastatin indications
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Genetic hypercholesterolemia
lowers LDL Raises HDL |
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Lipitor/Atorvastatin indications
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Decrease risk of MI
Genetic hypercholesterolemia lowers LDL; raises HDL Raises HDL |
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Zetia/Ezetimibe indications
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Antihyperlipidemia
Addresses both Dietary and genetic hypercholesterolemia |
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Zetia/Ezetimibe warnings
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Gemfibrozil and Fenofibrate increase Ezetimibe plasma levels
Cholestyramine lowers drug levels in plasma DO NOT give to patients with hepatatic insufficency Possible myopathy with statins |
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Vytorin indications
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Antihyperlipidemia
Genetic and dietary cholesterol |
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Vytorin warnings
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Myopathy
Avoid grapefruit juice, xs ROH and xs sunlight DO NOT take while pregnant |
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Tricor indications
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Antihyperlipidemic
hypercholesterolemia, mixed dyslipidemia hypertriglyceridemia |
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Tricor warnings
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Severe liver toxicity
Increase actions of Warfarin Cholestyamine decreases drug absorption Use with statins leads to rhabdomyolsis |
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Tricor/Fenofibrate lab tests
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check Warfarin levels
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Lopid/Gemfibrozil indications
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Antihyperlipidemia
Lowers cholesterol Lowers TG |
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Lopid/Gemfibrozil warnings
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May enhance effects of Lovastatin and anticoagulants such as Warfarin
Dizzyness blurred vision, myositis |
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Mevacor/Lovastatin indications
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Primary: Hypercholesterolemia
Lowers LDL cholesterol Raise HDL cholesterol Secondary: prevention of heart disease |
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Mevacor/Lovastatin blood property
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Highly protein-bound
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Niaspan warning
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Know if patient takes OTC Niacin
Flushing (treat with NSAIDs) |
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Niaspan/Niacin drug class
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Vitamin
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Lovastatin warnings
(beyond typical statin) |
May cause myopathy or rhabdomylosis with Gemfibrozil
Schedule liver tests every 4-6 wks during 1st 15 months Possible lenticular opacity |
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Lovaza/Omega-3-Acid ethyl ester indications
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Reduces high triglyceride levels (but not cholesterol levels)
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Lovaza/Omega-3-Acid ethyl ester warnings
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Watch for fish allergies
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Pravachol indications
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Hypercholesterolemia
Lowers LDL; Raises HDL Hyperlipoproteinema Lowers triglyceride levels |
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Pravachol warnings
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Avoid Gemfibrozil
Avoid immunosuppresants Avoid fatty diet Avoid xs ROH and sunlight |
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How is Pravachol different from other statins?
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Patient CAN consume grapefruit juice
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Crestor/Rouvastatin indications
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Very potent!
Hypercholesterolemia Lowers LDL; Raises HDL Hyperlipoproteinema Lowers triglyceride levels |
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Crestor (drug interaction )warnings
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Greatly increase INR levels with Warfarin
Coadmin with cyclosporins increase Crestor levels Antacids decrease Crestor levels Myopathy |
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Crestor warnings
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Myopathy
Take at night while cholesterol synth is at max Pregnancy Cat X |
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What classes of drugs lower triglycerides most effectively?
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Fibrates (Gemfibrazil, Fenofibrate)
Niacin Omega-3-Acids (Statins less than fibrates) |
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What classes of drugs lower cholesterol?
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Statins
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What drugs can raise triglyceride levels?
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Beta blockers
Thiazide diuretics Estrogen therapy |
