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52 Cards in this Set

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Zocor generic name
Simvastatin
Zocor/
Simvastatin drug class
Statin
Lipitor generic name
Atorvastatin
Lipitor/
Atorvastatin drug class
Statin
Zetia generic name
Ezetimibe
Zetia/
Ezetimibe drug class
Cholesterol absorption inhibitor
Vytorin generic name
Ezetimibe with Simvastatin
Tricor generic name
Fenofibrate
Tricor/
Fenofibrate drug class
Fibrate
Vytorin/
Ezetimibe with Simvastatin

drug class
Statin plus Cholesterol absorption inhibitor
Lopid generic name
Gemfibrozil
Lopid/
Gemfibrozil drug class
Fibrate
Mevacor generic name
Lovastatin (10, 20, 40 mg)
Mevacor/
Lovastatin drug class
statin
Niaspan generic name
Niacin extended release
Lovaza generic name
Omega-3-Acid ethyl ester
Lovaza/
Omega-3-Acid ethyl ester

drug class
Antihyperlipidemic

(Omega-3 fatty acid)
Pravachol generic name
Pravastatin
Pravachol/
Pravastatin drug class
Statin
Pravachol/
Pravastatin dosage
10-20 mg/day; adjust dosage at 4 week intervals until at a maximum of 40mg/day
Crestor generic name
Rosuvastatin
Crestor/
Rouvastatin drug class
Statin
Statins are also called?
HMG-CoA reductase inhibitors
Fibrates perform what function?
Lower triglyceride levels
Statin warnings
May increase Digoxin levels
Taking with Gemfibrozil can cause myopathy or rhabdomyolysis

Grapefruit juice raise drug levels in blood plasma
Myopathy (muscle pain)

Avoid excessive alcohol
Avoid excessive sunlight
Zocor/Simvastatin indications
Genetic hypercholesterolemia

lowers LDL
Raises HDL
Lipitor/Atorvastatin indications
Decrease risk of MI
Genetic hypercholesterolemia

lowers LDL; raises HDL
Raises HDL
Zetia/Ezetimibe indications
Antihyperlipidemia

Addresses both Dietary and genetic hypercholesterolemia
Zetia/Ezetimibe warnings
Gemfibrozil and Fenofibrate increase Ezetimibe plasma levels
Cholestyramine lowers drug levels in plasma
DO NOT give to patients with hepatatic insufficency
Possible myopathy with statins
Vytorin indications
Antihyperlipidemia

Genetic and dietary cholesterol
Vytorin warnings
Myopathy
Avoid grapefruit juice, xs ROH and xs sunlight
DO NOT take while pregnant
Tricor indications
Antihyperlipidemic

hypercholesterolemia,
mixed dyslipidemia
hypertriglyceridemia
Tricor warnings
Severe liver toxicity
Increase actions of Warfarin
Cholestyamine decreases drug absorption
Use with statins leads to rhabdomyolsis
Tricor/Fenofibrate lab tests
check Warfarin levels
Lopid/Gemfibrozil indications
Antihyperlipidemia

Lowers cholesterol
Lowers TG
Lopid/Gemfibrozil warnings
May enhance effects of Lovastatin and anticoagulants such as Warfarin

Dizzyness blurred vision, myositis
Mevacor/Lovastatin indications
Primary: Hypercholesterolemia
Lowers LDL cholesterol
Raise HDL cholesterol

Secondary: prevention of heart disease
Mevacor/Lovastatin blood property
Highly protein-bound
Niaspan warning
Know if patient takes OTC Niacin
Flushing (treat with NSAIDs)
Niaspan/Niacin drug class
Vitamin
Lovastatin warnings

(beyond typical statin)
May cause myopathy or rhabdomylosis with Gemfibrozil

Schedule liver tests every 4-6 wks during 1st 15 months

Possible lenticular opacity
Lovaza/Omega-3-Acid ethyl ester indications
Reduces high triglyceride levels (but not cholesterol levels)
Lovaza/Omega-3-Acid ethyl ester warnings
Watch for fish allergies
Pravachol indications
Hypercholesterolemia
Lowers LDL; Raises HDL

Hyperlipoproteinema
Lowers triglyceride levels
Pravachol warnings
Avoid Gemfibrozil
Avoid immunosuppresants
Avoid fatty diet
Avoid xs ROH and sunlight
How is Pravachol different from other statins?
Patient CAN consume grapefruit juice
Crestor/Rouvastatin indications
Very potent!
Hypercholesterolemia
Lowers LDL; Raises HDL

Hyperlipoproteinema
Lowers triglyceride levels
Crestor (drug interaction )warnings
Greatly increase INR levels with Warfarin
Coadmin with cyclosporins increase Crestor levels
Antacids decrease Crestor levels
Myopathy
Crestor warnings
Myopathy
Take at night while cholesterol synth is at max
Pregnancy Cat X
What classes of drugs lower triglycerides most effectively?
Fibrates (Gemfibrazil, Fenofibrate)
Niacin
Omega-3-Acids
(Statins less than fibrates)
What classes of drugs lower cholesterol?
Statins
What drugs can raise triglyceride levels?
Beta blockers
Thiazide diuretics
Estrogen therapy