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135 Cards in this Set
- Front
- Back
Hydrocodone/APAP
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CNS Depression
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Atrovastatin
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1) Active Liver Disease (elevated LFTs (ALT/AST)) 2) Pregnancy 3) Breastfeeding
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Levothyroxine
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1) Untreated Thyrotoxicosis 2) Untreated Adrenal Insufficiency
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Lisinopril
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1) HX of Angioedema 2) Pregnancy 3) Bilateral Renal Artery Stenosis
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Amoxicillin
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Hypersensitivity to amoxicillin, penicillin, or other beta lactams
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Esomeprazole
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Only Hypersensitivity
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Clopidogrel
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1) Active Bleeding 2) Intracranial Bleeding
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Metoprolol Tartrate
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1) Bradycardia (HR < 45 bpm) 2) Systolic BP < 100 mmHg 3) 2nd or 3rd Degree Heart Block 4) Cardiogenic Shock 5) Pheochromocytoma (as monotherapy / w/o alpha blockers)
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Montelukast
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Only Hypersensitivity
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Escitalopram
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1) Concurrent use or use within 2 wks of MAO inhibitors, such as phenelzine, tranylcypromine, and isoprocarboxazid, is contraindicated w/ all SSRIs. 2) Concurrent use of escitalopram w/ pimozide is contraindicated.
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Albuterol Inhaler
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Only Hypersensitivity
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Simvastatin
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1) Active Liver Disease (elevated LFTs (ALT/AST)) 2) Pregnancy 3) Breastfeeding 4) Concomitant use w/ strong 3A4 inhibitors
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Amlodipine
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Only Hypersensitivity
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Azithromycin
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1) Hypersensitivity to azithromycin or any macrolide antibiotic. 2) Concurrent use w/ cisapride, dronedarone, phenothiazines (mesordazine, thioridazine, etc.), and pimozide is contraindicated.
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Metformin
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1) Renal dysfunction (SCr less than or equal to 1.5 mg/dL in men or 1.4 mg/dL in women) and 2) metabolic acidosis (including diabetic ketoacidosis) are both contraindications. 3) Hepatic dysfunction is a relative contraindication. 4) If patient is undergoing radiologic studies involving iodine contrast dyes, then temporarily discontinue metformin 2 days before and after.
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Metoprolol Succinate
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1) Bradycardia (HR < 45 bpm) 2) Systolic BP < 100 mmHg 3) 2nd or 3rd Degree Heart Block 4) Cardiogenic Shock 5) Pheochromocytoma (as monotherapy / w/o alpha blockers)
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Hydrochlorothiazide
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1) Anuria 2) Concurrent use w/ dofetilide
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Rosuvastatin
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1) Active Liver Disease (elevated LFTs (ALT/AST)) 2) Pregnancy 3) Breastfeeding
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Furosemide
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Anuria
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Warfarin
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1) Active bleeding or increased bleeding risk 2) Pregnancy 3) Eclampsia or Pre-Eclampsia 4) Malignant HTN 5) Inadequate Mental State (not able to keep appointments for INR check) 6) Recent Major Surgeries 7) Spinal Puncture
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Fluticasone & Salmeterol
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1) Contraindicated for acute asthma or COPD episodes. Patients should use a short acting bronchodilator, such as ProAir HFA, instead. 2) Advair diskus is also contraindicated if the patient has a severe hypersensitivity to milk proteins (b/c the diskus contains lactose). 3) Status Asthmaticus
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Ibuprofen
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1) NSAID-Induced Asthma 2) NSAID-Induced Urticaria 3) Aspirin Triad
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Sertraline
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1) Concurrent use or use within 2 wks of MAO inhibitors, such as phenelzine, tranylcypromine, and isoprocarboxazid, is contraindicated w/ all SSRIs. 2) Concurrent use of sertraline w/ pimozide is contraindicated.
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Valsartan
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1) Pregnancy 2) Relative contraindication for Bilateral Renal Artery Stenosis.
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Zolpidem
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Only Hypersensitivity
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Oxycodone/APAP
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1) Severe Respiratory Depression 2) Prolonged use or the use of high doses just before birth in pregnancy. [Opioids can cause dependence and respiratory depression in the neonate.]
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Duloxetine
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1) Concurrent use or use within 2 wks of MAO inhibitors, such as phenelzine, tranylcypromine, and isoprocarboxazid, is contraindicated w/ all SSRIs. 2) Uncontrolled Narrow Angle Glaucoma. 3) Not recommended in hepatic impairment, or in renal impairment if CrCL is < 30 mL/min.
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Quetiapine
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Only Hypersensitivity
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Venlafaxine
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Concurrent use or use within 2 wks of MAO inhibitors, such as phenelzine, tranylcypromine, and isoprocarboxazid, is contraindicated w/ all SSRIs. Also, do not initiate an MAO inhibitor within 1 week of discontinuing venlafaxine.
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Tamsulosin
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Only Hypersensitivity
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Alprazolam
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1) Narrow Angle Glaucoma 2) Use w/ itraconazole or ketoconazole 3) Pregnancy
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Valsartan / Hydrochlorothiazide
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1) Pregnancy 2) Anurea 3) Hypersensitivity valsartan or to hydrochlorothiazide or other sulfonamide drugs 4) Relative contraindication for Bilateral Renal Artery Stenosis
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Trazodone
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Only Hypersensitivity
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Pioglitazone
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New York Heart Association Class III or IV Heart Failure
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Alendronate
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1) Hypocalcemia 2) Inability to sit up for 30 minutes after taking the medicine 3) Esophageal Emptying Abnormalities
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Sulfamethoxazole/Trimethoprim
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1) Hypersensitivity, including hypersensitivity to any sulfa drug 2) Severe renal or hepatic impairment 3) Near or at term pregnancy 4) Breastfeeding 5) Megaloblastic anemia due to folate deficiency
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Lansoprazole
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Only Hypersensitivity
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Clonazepam
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1) Severe Hepatic Impairment (Liver Disease) 2) Narrow Angle Glaucoma 3) Pregnancy
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Tramadol
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1) Hypersensitivity to tramadol or opioids 2) Opioid dependent patients 3) Acute Alcohol or Drug Intoxication. 4) The Extended Release dosage form is also contraindicated in severe renal or severe hepatic impairment.
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Levofloxacin
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Hypersensitivity to levofloxacin or other fluoroquinolones
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Fluoxetine
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1) Concurrent use w/ MAO inhibitors. Fluoxetine should not be initiated within 2 wks of MAO inhibitors and MAO inhibitors should not be used within 5 weeks of fluoxetine discontinuation. 2) Concurrent use w/ pimozide or thioridazine are contraindicated.
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Prednisone
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1) Systemic Fungal Infections & 2) Live vaccines should not be used within 3 months of prednisone.
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Omeprazole
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Only Hypersensitivity
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Atenolol
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1) Sinus Bradycardia (heart rate < 45 bpm) 2) 2nd or 3rd Degree Heart Block 3) Uncompensated Heart Failure 4) Pulmonary Edema 5) Untreated Pheochromocytoma 6) Cardiogenic Shock 7) Pregnancy
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Insulin Glargine
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Only Hypersensitivity
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Amoxicillin / Clavulanate
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1) Hx of liver dysfunction or cholestatic jaundice w/ amox/clav 2) Extended release, Augmentin XR, is also contraindicated in severe renal impairment (CrCL < 30 mL/min)
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Fenofibrate
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1) Severe Renal Dysfunction (CrCL < 30 mL/min) 2) Hepatic Impairment 3) Pre-Existing Gall Bladder Disease
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Celecoxib
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1) Hypersensitivity to celocoxib, sulfonamides, aspirin, or NSAIDs 2) CABG peri-operative pain
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Donepezil
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Relative contraindication for Bradycardia
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Ezetimibe & Simvastatin
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1) Acute Liver Disease 2) Increased transaminases or liver function tests (LFTs) 3) Pregnancy 4) Breastfeeding
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Cephalexin
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Only Hypersensitivity
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Mometasone
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Only Hypersensitivity
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Drospirenone & Ethinyl Estradiol
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1) Heavy Smokers (> 15 cigs/day) who are also older than 35 yo, 2) Pregnancy, 3) Hepatic Impairment, 4) Renal Impairment (CrCL < 50 mL/min), 5) Hx of or current Venous Thromboembolism (VTE), 6) Arterial Thromboembolic Event (Stroke or MI) within the past year, 7) Cornary Artery Disease (CAD), 8) Severe or Uncontrolled HTN, 9) Diabetes w/ vascular involvement, 10) Migraines w/ Focal Symptoms, 11) Prolonged Immobilization, 12) Abnormal Undiagnosed Vaginal Bleeding, 13) Breast Cancer, 14) Endometrial Cancer, & 15) Hx of Jaundice w/ use of oral contraceptives
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Vitamin D3
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1) Hypercalcemia 2) Malabsorption Syndrome 3) Vitamin D Toxicity or Hypervitaminosis D
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Ezetimibe
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Only Hypersensitivity
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Gabapentin
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Only Hypersensitivity
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Pregabalin
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Only Hypersensitivity
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Sildenafil
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Concurrent use w/ nitrates of any form.
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APAP/Codeine
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1) Significant Respiratory Depression 2) Acute or Severe Asthma 3) Paralytic Ileus 4) Hypercapnea (too much CO2 in the blood)
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Fluconazole
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Concurrent use w/ cisapride.
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Intranasal Fluticasone
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Nasal Ulcers or Trauma
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Losartan
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Pregnancy
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Propoxyphene-N/APAP
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1) Paralytic Ileus 2) Acute or Severe Asthma 3) Severe Respiratory Depression
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Valacyclovir
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Only Hypersensitivity
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Lorazepam
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1) Acute Narrow Angle Glaucoma 2) Severe Respiratory Impairment Contraindications Specific to the Injection Dosage Form: 1) Sleep Apnea 2) Intra-Arterial Injection (can only be given IV or IM).
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Pantoprazole
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Only Hypersensitivity
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Amlodipine/Benazepril
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1) HX of Angioedema 2) Pregnancy 3) Bilateral Renal Artery Stenosis
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Conjugated Estrogens
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1) Pregnancy 2) Abnormal Vaginal Bleeding (unseen / undiagnosed by a physician) 3) Hx or current VTE 4) Current stroke or MI (or one within the last year) 5) Breast Carcinoma (unless for metastatic disease at physician discretion) 6) Estrogen-Dependent Tumor 7) Liver Disease / Dysfunction
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Oseltamivir
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Only Hypersensitivity
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Tiotropium
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Only Hypersensitivity
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Aripiprazole
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Only Hypersensitivity
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Methylphenidate
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1) Idosyncratic Reactions to Sympathomimetic Amines 2) Significant Anxiety, Tension, or Agitation 3) Glaucoma 4) Use within 14 days of MAO inhibitors 5) Family Hx of Tourette's or Tics 6) Diagnosis of Tourette's or Tics 7) Patient is 65 years old or older 8) Cardiac Problems (structural problems, cardiomyopathy, CVD or CAD, arrhythmias) 9) Severe GI Stricture
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Digoxin
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Ventricular Fibrillation
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Fluticasone
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Nasal Ulcers or Trauma
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Fexofenadine
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Only Hypersensitivity
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Olmesartan
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Pregnancy
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Pravastatin
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1) Active Liver Disease 2) Unexplained Increase in LFTs 3) Pregnancy 4) Breastfeeding
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Triamterene/Hydrochlorothiazide
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1) Hypersensitivity, including Hypersensitivity to Sulfonamides 2) Hyperkalemia 3) Anurea 4) Significant Renal Impairment
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Methylprednisolone
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1) Systemic Fungal Infections 2) Live vaccines should not be used within 3 months of methylprednisolone.
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Cyclobenzaprine
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Most have to do w/ the cardiovascular system: 1) Use within 14 days of MAO Inhibitors 2) Hyperthyroidism 3) Heart Failure 4) Arrhythmias 5) Heart Block (or conduction disturbances) 6) Use within the acute phase of an MI
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Clonidine
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Only Hypersensitivity
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Risedronate
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1) Hypocalcemia 2) Inability to sit up for 30 minutes after taking the medicine 3) Esophageal Emptying Abnormalities
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Diazepam
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1) Severe Hepatic Impairment (Liver Disease) 2) Myasthenia Gravis 3) Narrow Angle Glaucoma 4) Severe Respiratory Insufficiency 5) Sleep Apnea
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Carisoprodol
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Acute Intermittent Porphyria (a rare hereditary disorder in which the heme portin of hemoglobin is not made properly)
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Promethazine
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1) Coma 2) Treatment of Lower Resipratory Tract Symptoms (including asthma) 3) Children < 2 Years Old 4) Intra-Arterial or Subcutaneous Administration
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Memantine
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Only Hypersensitivity
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Potassium Chloride
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1) Hyperkalemia 2) GI Tract Obstructions
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Citalopram
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1) Concurrent use or use within 2 wks of MAO inhibitors, such as phenelzine, tranylcypromine, and isoprocarboxazid, is contraindicated w/ all SSRIs. 2) Concurrent use of citalopram w/ pimozide is contraindicated.
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Meloxicam
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1) Hypersensitivity to Meloxicam or other NSAIDs 2) Perioperative pain due to Coronary Artery Bypass Graft (CABG)
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Latanoprost
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Only Hypersensitivity
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Carvedilol
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1) Decomposed HF 2) Asthma or Bronchospastic Conditions 3) 2nd or 3rd Degree Heart Block 4) Severe Bradycardia 5) Cardiogenic Shock 6) Severe Hepatic Impairment
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Oxycodone
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1) Significant Respiratory Depression 2) Acute or Severe Asthma 3) Paralytic Ileus
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Paroxetine
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1) Concurrent use or use within 2 wks of MAO inhibitors, such as phenelzine, tranylcypromine, and isoprocarboxazid, is contraindicated w/ all SSRIs. 2) Concurrent use of paroxetine w/ either thioridazine or pimozide is also contraindicated.
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Olmesartan/Hydrochlorothiazide
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1) Pregnancy 2) Anuria 3) Concurrent use w/ dofetilide
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Tadalafil
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Concurrent use w/ nitrates of any form.
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Sitagliptin
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Only Hypersensitivity
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Ciprofloxacin
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Concurrent use w/ tizanidine
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Amitriptyline
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1) Concurrent use or use within 2 wks of MAO inhibitors, such as phenelzine, tranylcypromine, and isoprocarboxazid 2) Acute Recovery Period after MI 3) Concurrent use w/ Cisapride
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Naproxen
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1) Hypersensitivity to Naproxen or other NSAIDs 2) Perioperative pain due to Coronary Artery Bypass Graft (CABG)
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Niacin ER
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1) Active Liver Disease or Significantly Increased LFTs 2) Peptic Ulcer Disease 3) Arterial Hemorrhage
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Allopurinol
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Only Hypersensitivity
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Losartan/Hydrochlorothiazide
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1) Pregnancy 2) Anuria 3) Concurrent use w/ dofetilide
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Tolterodine
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1) Urinary Retention 2) Gastric Retention 3) Uncontrolled Narrow Angle Glaucoma
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Lisinopril/Hydrochlorothiazide
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1) HX of Angioedema 2) Pregnancy, 3) Bilateral Renal Artery Stenosis 4) Anuria, 5) Concurrent use w/ dofetilide
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Norgestimate & Ethinyl Estradiol
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1) Heavy Smokers (> 15 cigs/day) who are also older than 35 yo, 2) Pregnancy, 3) Hepatic Impairment, 4) Hx of or current Venous Thromboembolism (VTE), 5) Arteriol Thromboembolic Event (Stroke or MI) within the past year, 6) Cornary Artery Disease (CAD), 7) Severe or Uncontrolled HTN, 8) Diabetes w/ Vascular Involvement, 9) Migraines w/ Focal Symptoms, 10) Prolonged Immobilization, 11) Abnormal Undiagnosed Vaginal Bleeding, 12) Breast Cancer, 13) Endometrial Cancer, 14) Hx of Jaundice w/ use of Oral Contraceptives
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Penicillin VK
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Only Hypersensitivity
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Codeine & Guaifenesin
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Asthma
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Glyburide
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1) Type 1 Diabetes Mellitis, 2) Diabetic Ketoacidosis, 3) Use w/ Bosentan
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Fluticasone Inhaler
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Use as primary treatment of status asthmaticus or acute bronchospasms. Inhaled corticosteroids do not take effect fast enough to treat a current attack and should only be used for longterm therapy.
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Rabeprazole
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Only Hypersensitivity
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Lisdexamfetamine
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1) Advanced Arteriosclerosis 2) Symptomatic Cardiovascular Disease 3) Moderate-To-Severe HTN 4) Hyperthyroidism 5) Glaucoma 6) Hx of Drug Abuse 7) Concurrent use w/ or use within 2 wks of MAO inhibitors (phenylzine, tranylcypromine, isoprocarboxazid, etc.)
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Isosorbide Mononitrate
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Concurrent use w/ phosphodiesterase-5 inhibitors: sidenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra)
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Lamotrigine
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Only Hypersensitivity
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Olanzapine
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Only Hypersensitivity
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Lovastatin
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1) Active Liver Disease 2) Unexplained Increase in LFTs 3) Pregnancy 4) Breastfeeding
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Ethinyl Estradiol & Etonogestrel Vaginal Ring
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1) Hx of Venous Thromboembolic Disorders, such as Deep Vein Thrombosis (DVT) or Pulmonary Embolism (PE), 2) Major Surgery w/ Prolonged Immobilization, 3) Cerebral Vascular Disease, 4) Cornary Artery Disease (CAD), 5) Valvular Heart Disease w/ Complications, 6) Severe HTN, 7) Diabetes Mellitus w/ Vascular Involvement, 8) Migraines w/ Focal Symptoms , 9) Presence or Personal Hx of Breast Cancer Pregnancy, 10) Endometrial Cancer, 11) Undiagnosed Abnormal Genital Bleeding, 12) Active Liver Disease or Tumor, 13) Cholestatic Jaundice of Pregnancy, 14) Hx of Jaundice w/ use of Hormonal Contraceptives, 15) Heavy Smokers (> 15 cigs/day) who are also older than 35 yo, 16) Pregnancy
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Bupropion
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1) Seizure Disorder 2) Hx of Anorexia or Bulimia 3) Concurrent use or use within 2 wks of MAO inhibitors 4) Currently undergoing abrupt discontinuation of ethanol or sedatives 5) Patient receiving other dosage forms of bupropion.
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Doxycycline
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Children < 8 yo (unless used as treatment for anthrax exposure or tickborne rikettsial disease) [Reason: It can cause permanent tooth discoloration.]
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Enalapril
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1) HX of Angioedema 2) Pregnancy
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Irbesartan
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1) Pregnancy 2) Relative contraindication for Bilateral Renal Artery Stenosis.
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Amphetamine & Dextroamphetamine
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1) Advanced Arteriosclerosis 2) Symptomatic Cardiovascular Disease 3) Moderate-To-Severe HTN 4) Hyperthyroidism, 5) Glaucoma 6) Hx of Drug Abuse 7) Concurrent use w/ or use within 2 wks of MAO inhibitors (phenylzine, tranylcypromine, isoprocarboxazid, etc.)
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Ibandronate
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1) Hypocalcemia 2) Inability to sit up for 60 minutes after taking the medicine 3) Esophageal Emptying Abnormalities
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Eszopiclone
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Only Hypersensitivity
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Ipratropium & Albuterol Inhaler
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Only Hypersensitivity
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Folic Acid
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Only Hypersensitivity
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Meclizine
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Only Hypersensitivity
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Ethinyl Estradiol & Norethindrone
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1) Breast Cancer or other estrogen- or protestin-dependent neoplasms, 2) Hepatic Tumors, 3) Pregnancy, 4) Undiagnosed, abnormal uterine bleeding, 5) Those at high risk of venous thromboembolism, including patients who have cardiovascular disease, coronary artery disease, diabetes w/ vascular disease, Hx of deep vein thrombosis (DVT) or pulmonary embolism (PE), 6) Hypercoagulopathies, 7) Headaches w/ focal symptoms, 8) Migraines in patients greater than 35 yo, 9) Uncontrolled HTN, 10) Valvular or rhythm abnormalities of the heart, 11) Women who are greater than 35 years old who also smoke cigarettes.
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Buprenorphine & Naloxone
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Only Hypersensitivity
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Raloxifene
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1) Hx of Venous Thromboembolic Disorders, such as Deep Vein Thrombosis (DVT) or Pulmonary Embolism (PE) 2) Pregnancy 3) Breastfeeding [Raloxifene is only for women who are postmenopausal.]
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Omega-3-Acid Ethyl Esters
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Only Hypersensitivity
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Lidocaine Patch 5%
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Hypersensitivity to local anesthetics of the amide type, or to any component of the product.
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Ramipril
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1) HX of Angioedema 2) Pregnancy
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Benazepril
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1) HX of Angioedema 2) Pregnancy
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Verapamil
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1) Bradycardia 2) 2nd or 3rd Degree AV Block 3) Sick Sinus Syndrome 4) Congestive Heart Failure (CHF) 5) Patients w/ atrial flutter or atrial fibrillation and an accessory bypass tract (e.g. Wolff-Parkinson-White Syndrome or Lown-Ganong-Levine Syndrome) 6) Ventricular Tachycardia
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Ranitidine
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Only Hypersensitivity
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