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21 Cards in this Set

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Active ingredients for Zestoretic
lisinopril & hydrochlorothiazide
Use with caution in pts w/ cirrhosis, gout, impaired renal or hepatic function, diabetes, and in pts who are taking corticosteroids or ACTH
Zestoretic /lisinopril & HCTZ
thiazides used as HTN first line agents to decrease ECF vol. S/e of thiazides inlude hypersensitivity reactions --careful w/ corticosteroids
Active ingredients for Lotrel
amlodipine besylate & benazepril HCl
May cause rare increase in angina or myocardial infarction on starting therapy or increasing dose.
amlodipine -CCB
benazepril -ACE-I
Active ingredient for Cozaar
losartan potassium
The most common adverse effects are upper respiratory infection, diarrhea, dizziness, nasal congestion, and cough. Rare cases of rhabdomylosis have been reported in patients receiving angiotensin II receptor blockers.
Active ingredient for Catapres & Catapres TTS
clonidine hydrochloride
May cause dry mouth, drowsiness and contact dermatitis (transdermal 15-20%)
inhibition of bulbar sympathetic cardioaccelerator and sympathetic vasoconstrictor centers
Inhibit bulbar sympathetic cardioaccelerator and sympathetic vasoconstrictor to reduce symp. outflow from the CNS -> decreases PVR, HR, BP
Sympatholytic agents, centrally-acting drugs,
a2-adrenoceptor agonist in CNS and periphery
Blood Pressure control may be decreased when used with trycyclic antidepressants
Start w/ 0.1mg bid, then increase dosage by increments of 0.1mg to 0.2mg per day until desired response is achieved. Normal dosage range is 0.2mg to 0.8mg per day in divided doses
Fetal & neotanal morbidity and death when administered to pregnant women. d/c when pregnancy is detected
Cozaar/ losartan potassium
Use with caution in patients with collagen vascular diseae (may cause agranulocytosis), or aortic stenosis, & in patients undergoing surgery or anesthesia.
Lotrel/ amlodipine besylate & benazepril HCl, Altace/ ramipril, Lotensin/ benazepril
agranulocytosis -severe blood disorder
aortic stenosis -aorta constriction
Lotensin/ benazepril (ACE-I)
Available dosage forms & strength
Tablets: 5,10,20,40mg
May be take with food or milk if GI upset occurs
Catapres/ clonidine hydrochloride
Adverse effects -cough
Zestril /lisinopril & HCTZ
Lotensin /benazepril
Altace /ramipril
Cozaar /losartan
Lotrel /amlodipine besylate & benazepril
Because of potassium-sparing effects, use caution when given w/ potassium sparing diuretics and potassium supplements -risk of hyperkalemia
Lotensin/ benazepril hydrochloride, Altace/ ramipril, Zestoretic/ lisinopril & HCTZ, Lotrel/ amlodipine besylate & benazepril HCl
HTN treatment -alone or in combination with thiazide diuretics: initially give 2.5mg once daily, maintenance dose is between 2.5 and 20mg in one or two doses
Altace/ ramipril
block the vasoconstrictor and aldosterone secreting effects of Ang II by selectively blocking the binding of Ang II to the AT1 receptor found in many tissues
Cozaar/ losartan
Only available as capsules
Altace/ ramipril, Lotrel/ amlodipine besylate & benazepril HCl
timing of dose is important because of increased diuresis. usually given in early a.m.
Zestoretic/ lisinopril & HCTZ