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106 Cards in this Set
- Front
- Back
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What is Metaglip
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Glipizide/metformin(sulfonylurea/biguanide)
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95. Indication of insulin?
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Type I, II DM, treatment of hyperkalemia, severe DKA
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96. How to prevent lipodystrophy for using insulin?
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Rotate injection site
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97. Initial dose of NPH for Type I & II DM?
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0.5 – 1 Unit/kg/day
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98. Draw regular insulin into syringe first then add the NPH insulin to the syringe?
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YES
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99. Generic name of Humalog?
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Insulin Lispro Human (0.5- 1 Unit/kg/day; 15 mins before meals)
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100. Dosage form of Amaryl (glimepiride)?
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1, 2, 4 mg tabs
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101. Amaryl is contraindicated in Type I DM?
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yes
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102. Drugs affecting pioglitazone (Actos)?
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Alcohol (hypoglycemia), CYP3A4 inhibitors increase effect, ketoconazole increases effect, CYP3A4 inducers decrease effect; Oral contraceptives decreases efficacy of Actos
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103. Initial dose of Avandia (rosiglitazone)?
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4 mg daily
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104. Generic name of Neosporin?
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Neomycin-polymixin B
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105. Common ADR of isoniazid (INH, Laniazid, Nydrazid)?
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Peripheral neuropathy, increase LFT, abdominal pain, HEPATITIS
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106. Rifampin (Rifadin) is potent, broad-spectrum hepatic enzyme inducer?
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YES
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108. Max dose of sildenafil (Viagra)?
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100 mg/day
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109. Severe ADR of sildenafil?
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Priapism (painful erection)
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110. Absolute contraindication of sildenafil?
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Concomitant nitrates
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111. Indication of cyclosporine (Neoral)?
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Prevention of organ transplant rejection, rheumatoid arthritis, psoriasis
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112. Counseling patient about cyclosporine?
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Avoid grapefruit juice because it increases cyclosporine blood levels
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113. Sandimmune and Neoral are bioequivalent?
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NO
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114. Verapamil and diltiazem increase cyclosporine blood levels?
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YES
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115. Folic acid effect on drug?
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Decreases the effect of cyclosporine
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116. Usual and max dose of loratadine (Claritin) for 2-6 year olds with allergic rhinitis, urticaria?
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5 mg QD Max 5 mg/day >6 year old 5-10 mg/daily
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117. Indication of mupirocin (Bactroban) ointment?
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Impeitgo
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118. Indication of metronidazole (MetroGel, 0.75% topical gel)?
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Treatment of inflammatory papules and pustules of rosacea
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119. Usual dose of Duragesic?
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25 mcg/hr to 400 mcg/hr
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120. SE of Duragesic?
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Constipation, NV, dizziness
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121. Morphine is CIII?
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no
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122. SE of morphine?
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Constipation, NV, dizziness, dry mouth
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123. Oxycontin is CIII?
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no
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124. Dose of nabumetone?
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500 mg BID
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125. Nabumetone is an NSAID?
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yes
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126. Sever ADR of metformin?
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Lactic acidosis
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127. Dose of glyburide?
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5 mg/day
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128. Decrease hypoglycemic effect of insulin?
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HIV antivirals, oral contraceptives, phenytoin, NOT ACEI
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129. Pregnancy category of oral contraceptives?
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x
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130. SE of oral contraceptives?
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Edema, breast tenderness, HTN
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Edema, breast tenderness, HTN
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MI, breast cancer, undiagnosed abnormal genital bleeding
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132. Prempro’s SE?
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Vaginal bleeding, breast tenderness, weight gain, HTN (HA?)
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133. MOA of Keflex?
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Inhibits bacterial cell wall growth
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134. Dose of Claritin?
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10 mg/day
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135. Dose of dopamine IV?
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1-5 mcg/kg/min
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136. Indications of Klonopin?
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Panic disorder, absence seizures
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137. Indication of Buspar?
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GAD
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138. Dose of Zerit?
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40 mg BID
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139. Dose of stavudine?
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40 mg BID (Zerit)
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140. Indication of altepase?
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Acute MI, acute ischemic stroke, pulmonary embolism
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141. Trade name of itraconazole?
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Sporanox
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142. Indication of valacyclovir?
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Genital herpes
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143. Dose of benazepril for HTN?
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10 mg/day
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144. Initial and maintenance dose of losartan (Cozaar)?
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Initial: 50 mg/day Maintenance: 25-100 mg/day (1-2 divided doses
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145. Losartan is absolutely contraindicated to pregnancy?
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NO, but recommend discontinuing ASAP
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146. Common ADR of digoxin (Lanoxin, Digitek)?
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HA, dizziness, N, D, anorexia
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147. Severe ADR of Digitek?
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Atrial tachycardia, atrial-ventricular disassociation, heart block, ventricular fibrillation, anxiety, BLURRED OR YELLOW VISION, hallucination, gynecomastia
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148. Which drugs cause significant decline in glomerular filtrate or tubular secretion with digoxin?
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Amphotericin and aminoglycoside
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149. Drugs increase digoxin levels?
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Amiodarone, cyclosporine, clarithromycin, itraconazole
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150. When do you check digoxin levels?
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Check serum levels just before the next dose or >=6-8 hours after the last dose (0.8-2 ng/mL)
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151. Maintenance dose of Tenormin (atenolol) for HTN?
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50-100 mg/d
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152. Maximum dose of metoprolol for HTN?
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450 mg total daily dose
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153. Absolute contraindication of metoprolol
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Third degree AV block, sinus bradycardia, cardiogenic shock, overt cardiac failure
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154. Dosage forms of diltiazem (Tiazac)?
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Tablets, capsules, injectables
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155. Common ADR, of diltiazem?
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Peripheral edema, HTN, flushin, HA, bradycardia, asthenia (loss of strength
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156. Common ADR of furosemide (Lasix)?
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Hyponatremia, hypokalemia, hypochloremic alkalosis, HA, diarrhea, orthostasis
Severe: ototoxicity |
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157. Common ADR of Imdur?
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Severe HA
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158. Indication of Imdur?
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Prophylaxis and long-term maintenance of recurrent angina
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159. Absolute contraindication of Imdur?
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Cerebral hemorrhage, recent head trauma, pericardial tamponade, constrictive pericarditis
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160. Imdur effect on sildenafil (increase hypotensive effect)?
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yes
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161. Common ADR of dopamine (Intropin)?
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HTN
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162. Absolute contraindication of dopamine?
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Pheochromocytoma, uncorrected tachyarrhythmias, ventricular fibrillation
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163. Dopamine decreases the effectiveness of tricyclic antidepressants?
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YES
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164. Max oral dose of sumatriptan (Imitrex)?
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200 mg QD 12 mg SQ
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165. Common ADR of sumatriptan (Imitrex)?
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Parasthesias, hot/cold skin sensations, flushing, fatigue, somnolence, photosensitivity
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166. Absolute contraindications to Imitrex?
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Ischemic heart disease, angina, CVA, TIA, MI, uncontrolled HTN, use of another 5HT1 agonist within 24 hours, ergotamine use
DO NOT TAKE WITH MAOI or recently before or after |
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167. Initial dose of Xanax (alprazolam) for GAD?
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0.25 – 0.5 mg TID
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168. Maintenance dose of Klonopin for panic disorder?
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1-2 mg/day
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169. Initial dose for diazepam (Valium) for anxiety disorder?
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6-15 mg/day MAX 40 mg/day
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170. Initial dose of Buspar (buspirone) for GAD?
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10-15 mg/day (2-3 divided doses)
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171. Indication for carbamazepine?
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Seizures
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172. Treatment for reaction of amphotericin B?
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Benadryl and APAP (infuse over at least 2 hours)
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173. Dosage form of Nystatin?
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Oral suspension: 50, 150, 500 million Units
Powder: 1, 2.5 billion Units 100,000 Units/mL (Mycostatin) Tablets: 500,000 Units |
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174. Drugs increasing the concentration of itraconazole (Spoanox)?
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Macrolide antibiotics (clarithromycin), protease inhibitors (indinavir, ritonavir)
Enzyme inducer: carbamazepine, phenobarbital, phenytoin, rifampin |
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175. Absolute contraindication of Ziagen (abacavir)?
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Hypersensitivity reaction
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176. Dose of Zerit (stavudine) for HIV infection?
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Adult: >=60 kg 40 mg BID
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177. Severe ADR of Norvir (ritonavir)?
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HYPERGLYCEMIA (borderline diabetic), hypersensitivity, pancreatitis, redistribution/accumulation of body fat, increase total triglyceride or cholesterol
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178. Ritonavir decrease the level of theophylline by 43%?
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yes
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179. Ritonavir increases the level of rifabutin (Mycobutin)?
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yes
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180. Rifampin decreases ritonavir AUC by 35%?
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yes
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181. What drug class of Cytoxan (cyclophosphamide)?
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Alkylating agent Pregnancy D
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182. Common ADR of cyclophosphamide?
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Alopecia, mucositis, N, V delayed, D, leukopenia, severe hemorrhagic cystitis)
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183. SE of doxorubicin (Adriamycin)?
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Cardiotoxicity
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184. Contraindication of doxorubicin?
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CHF, severe hepatic dysfunction
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185. What to recommend if extravasation occurs with doxorubicin?
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Treat with topical DMSO and cold compress
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186. Dosage form of 6-mercaptopurine?
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50 mg tablet
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187. ADR of 6-MP?
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Leukopenia, thrombocytopenia, anemia, hepatotoxicity, N, drug fever, hyperpigmentation
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188. What drug does 6-MP have an effect on?
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Warfarin
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189. Indication of methotrexate (Rheumatrex)?
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Non-oliguric rheumatoid arthritis
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190. Class of cisplatin (Platinol)?
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Platinum
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191. Common ADR of paclitaxel (Taxol)?
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Bradycardia, peripheral neuropathies, myalgias
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192. Indication of Cardura (doxazosin)?
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Treatment of HTN, benign prostatic hyperplasia
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193. Indication of Hytrin (terazosin)?
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HTN, BPH
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194. Indication of Flomax (tamsulosin)?
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BPH
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195. Dose of tamsulosin
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0.4 mg tablet
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196. What drug class are doxazosin and terazosin?
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Alpha-1 blocker
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197. Pregnancy category of clinidine (Catapres)?
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C
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198. Initial and max dose of benazapril (Lotensin)?
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Initial: 10 mg/day Max: 40 mg/day
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199. What drug does benazapril have an effect on?
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K-sparing diuretics, K-supplements, digoxin
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200. Initial dose of captopril (Capoten) for HTN?
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25 mg po BID-TID
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