Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
24 Cards in this Set
- Front
- Back
|
Terbutaline Class/MOA
|
Beta-2 Agonist--> increases adenyl cyclase & cAMP--> relax uterine muscle
|
|
|
Terbutaline Action
|
Tocalytic (inhibits labor)
|
|
|
Terbutaline SE
|
Tremor, Tachycardia
|
|
|
Magnesium Action
|
Tocolytic
|
|
|
Mg MOA
|
Inhibits extracellular Ca2+ entry into uterine smooth muscle--> prevents contraction
|
|
|
Tocalytic that is a Ca Channel blocker
|
Nifedipine
|
|
|
Nifedipine MOA
|
Blocks Ca channel by stabilitzing voltage gated L type--> prevents contraction
|
|
|
Nifedipine SE
|
Edema, constipation, may precipitate MI in pts w/ HTN
|
|
|
Indomethacin Class/Action
|
Non selective COX inhibitor; Tocolytic
|
|
|
Inhibits COX 1 & 2--> decreases PG--> decreases uterine contractions
|
Indomethacin
|
|
|
Indomethacin SE
|
Impaired renal function, ulcers, vertigo limits dosing in gout
|
|
|
Dinoprostone & Misoprostil Class
|
PGE2/analog
|
|
|
MIsoprostil MOA
|
Binds EP-2/EP-3 prostanoid receptors--> increases amplitude and freq of uterine contractions
Effacement of cervix |
|
|
Misoprostil and Dinoprostone action
|
Induce labor!
Can be used as an abortifactant (misoprostil) |
|
|
Dinoprostone MOA
|
Stim myometrium to contract
Softens, effaces and dilates uterus/cervix maybe by collagen degredation |
|
|
Metoclopramide Class
|
D2 antagonist
|
|
|
Metoclopramide MOA/Action
|
Inhibits dopamine binding--> uninhibits prolactin secretion--> LACTATION!!!
|
|
|
MIsoprostil SE
|
miscarriage
Diarrhea |
|
|
Metoclopramide SE
|
Tardive dyskinesia
|
|
|
Oxytocin Action
|
Stimulates labor and lactation
|
|
|
Oxytocin MOA
|
Binds Oxytocin receptors in uterus muscle--> increases intracellular Ca--> induces uterine contraction
|
|
|
Oxytocin SE
|
Uterine rupture
Placental abruption |
|
|
Atosiban Class/MOA
|
Oxytocin inhibitor
|
|
|
Atosiban Action
|
Tocolytic
|
