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168 Cards in this Set

  • Front
  • Back
What are the four primary tissue classes?
1. Epithelial
2. Connective
3. Nervous
4. Muscular
State the functions of Epithelial Tissue? (epithelia is plural)
covers body surfaces, lines hollow organs, body cavities, and ducts; it also forms glands. This tissue allows the body to intereact with both its internal and external environments.
State the functions of Connective Tissue?
protects and supports the body and its organs. Various types of connective tissue bind organs together, store energy reserves as fat, and help provide immunity to disease-causing organisms.
State the functions of Muscular Tissue?
is composed of cells specialized for contraction and generation of force. In the process, muscular tissue generates heat that warms the body.
State the functions of Nervous Tissue?
detects changes in variety of conditions inside and outside the body and responds by generating nerve impulses that activate muscular contractions and glandular secretions.
What is a cell junction?
*Contact points between the plasma membranes of tissue cells.
*Keeps cells together so they can form tissues.
What are four important types of cell junctions?
1) Desmosomes
2) Hemidesmosomes
3) Tight junctions
4) Gap junctions
What are desmosomes? (desmo- = band)
* Spot-weld-like junctions that prevent cells from seperating under tension.
* Extend into the intercellular space adjacent cell membranes and attach cells to one another.
What are hemidesmosomes?
(hemi- = half)
* Anchor cells not to each other but to the basement membrane.
What are tight junctions?
*Weblike strands of transmembrane proteins that fuse together to outer surfaces of adjacent plasma membranes to seal off the passageways between adjacent cells.
What are gap junctions?
*Junctions that are not fused but seperated by connexons(tunnels) which serve to allow diffusion of cytosol and cell-to-cell communication.
What is an apical surface?
*Epithelial cell facing the body surface, a body cavity, the lumen of an organ, or a tabular duct that receives cell secretions.
What is a basal surface?
*Deepest layer of epithelial cells.
*Opposite apical surface.
What are lateral surfaces?
*Epihelial cells, which face adjecent cells on either side.
*May contain tight junctions, adherens junctions, desmosomes, and/or gap junctions.
What is the basal membrane?
A thin layer that commonly consists of two layers, the basal lamina and reticular lamina.
What is the basal lamina? (lamina = thin layer)
*the layer closer to the epithelial cells.
*produced by epithelial cells.
What is reticular lamina?
*the layer closer to the underlying connective tissue *contains proteins such as collagen produced by connective tissue connective tissue cells.
What is fibroblast?
*connective tissue cells
What does avascular mean?(a- = without; vascular= vessel)
*relying on blood vessels of the adjacent connective tissue to bring nutrients and remove waste through diffusion.
How are epithelial cells classified?
Two types of classification:
1) By layers
2) By shape
What are the different types of layers among epithelial cells?
Three types of layers:
1) Simple
2) Psudostratified epithelium
3) Stratified
What are the different types of shapes among epithelial cells?
Four types of shapes:
1) Squamous
2) Cuboibdal
3) Columnar
4) Transitional
Describe simple (unilaminar) epithelium
*a single layer of cells that functions in diffusion, osmosis, filtration, secretion, or absorption.
Define secretion
* the production and release of substances such as mucus, sweat, or enzymes.
Define absorption
* the intake of fluids or other substances such as digested food from the intestinal tract.
Describe pseudostratifed epithelium (pseudo- = false)
* appears to have multiple layers of cells but actually doesn't.
* contain globlet cells
What are goblet cells?
* cells that secret mucus
Describe stratified (multilaminar) epithelum (stratum=layer)
* layers that consist of two or more cells.
Describe squamous cells
* arranged like floor tiles
* are thin and allow for rapid passages of substances
Describe cuboidal cells
* are as tall as they are wide
* shaped like cubes or hexagons.
* may have microvilli at their apical surface
* secrete or absorb
Desbribe columnar cells
* much taller than they are wide, like columns
* protect underlying tissue
* may have cilia or microvilli
* often secrete or absorb
Describe transitional cells
* cells that chage shape, from flat to cuboidal and back
* found in organs such as urinary bladder that strecth and distend.
Epithelial tissue may be further divided into two types, what are they?
1) Covering and lining epithelium (-thelium = covering)
2) Glandular epithelium ( makes up the secreting portion of glands)
Where in the body can we find simple squamos epithelium?
Linings of heart, blood vessels, lymphatic vessels, air sacs and lungs, inner surface of eardrum and serous membranes such as peritoneum, pericardium, and pleura.
What are the functions of simple squamos epithelium?
Filtration, diffusion, osmosis, and secretion in serous membranes.
What is endothelium? (endo- = within; - thelium = covering)
* Simple squamos epithelium linings of the cardiovascular and lymphatic systems.
What is mesothelium? (meso- = middle)
* The simple squamos epithelium that forms the epithelial layer of serous membranes, such as peritoneum, pleura, or pericardium.
Where in the human body can simple cuboidal epithelium be found?
*Surfaces of ovary, linings of anterior surface of capsule of the lens of the eye, kidney tubules, and small ducts of many glands suck as the thyroid gland and the ducts of some glands such as the pancreas.
Nociliated simple columnar epithelium contains two types of cells; what are they?
Columnar epithelial cells with microvilli at their apical surface and goblet cells.
Describe microvilli and state its function
fingerlike cytoplasmic projections, increase the surface area of the plasma membrane, thus increasing the rate of absorption by the cell.
Describe goblet cells
modified columnar epithelial cells that secrete mucus, at their apical surfaces. Before it is released, mucus accumulates in the upper portion of the cell, causing it to bulge out and making the whole cell resemble a goblet or wine glass.
What is the function of a goblet cell?
*Its mucus serves as a lubricant for the linings of the digestive, respiratory, and reproductive tracts, and most urinary of the tract.
*Mucus also helps prevent destruction of the stomach lining by acidic gastric juice secreted by the stomach.
Where can noncilated simple columnar epithelium be found and what is its function?
*Linings of the gastrointestinal tract, ducts of many glands, and gallbladder.
*Secretion and absorption
Where can ciliated simple columnar epithelium be found?
Linings of some bronchioles(small tubes) of respiratory tract, uterine (fallopian) tubes, uterus, some paranasal sinuses, central canal of spinal cord and ventricles of the brain.
What is the function of ciliated simple columnar epithelium?
Move mucus and other substances by cilary action.
Where can we find pseudostratified columnar epithelium?
Ciliated: linings of airways of most of upper respiratory tract.
Nonciliated:lininings if larger ducts of many glands, epididymis, and part of the male urethra.
What type of cells may contain cilia or microvilli aswell as goblet cells?
Columnar epithelium both simple and pseudostratified.
Where can we find stratified squamous epithelium?
*Keratinized variety forms superfial layer of skin
*Nonkeratinized variety lines wet surfaces, such as lining of the mouth, esophagus, part of epiglottis, part of pharynx and vagina, and covers the tongue.
What is the function of stratified squamous epithelium?
Its function is Protection.
Where can we find keratinized cells?
In stratified squamous epithelium; skin.
Where can we find cuboidal epithelium?
In ducts of adult sweat glands and esophageal glands and part of male urethra.
What is the function of stratified cuboidal epithelium?
Proctection and limited secretion and absorption.
Describe keratin and state its function
* a tough, fibrous intracellular protein that helps protect the skin and underlying tissues from heat, microbes and chemicals.
Where can stratified columnar epithelium be found?
Linings of urethra, large excretory ducts of some glands, such as espphageal glands, small areas in anal mucous membrane, and part of the conjunctive of the eye.
What is the function of stratified columnar epithelium?
Proctection and absorption
Where can transitional epithelium be found and what is its function?
*Linings of urinary bladders and portions of ureters and urethra.
* Permits secretion
What is a gland?
*A single cell or group of cells that secrete substances into ducts(tubes), onto a surface, or into blood.
*Two types: Endocrine or Exocrine
Where do endocrine glands secrete?
Secretions enter the interstitial fluid and then diffuse directly into the bloodstream without flowing through a duct.
* These secretions are called hormones.
What are hormones?
secretions that regulate many metabolic and physiological activities to maintain homeostasis.
What are some examples of endocrine glands?
The pituitary, thyroid, and adrenal glands.
Where do exocrine glands secrete their products? (exo- = outside; -crine = secretion)
Into ducts that empty onto the surface of a covering and lining epithelium such as the skin surface or the lumen of a hollow organ.
What kind of products do exocrine glands secrete?
*Mucus, sweat, oil, earwax, saliva, and digestive enzymes.
How are exocrine glands classified?
*Unicellular
*Multicellular
Describe unicellular glands
Single-celled glands (i.e. goblet cells)
Describe multicellular glands
*composed of many cells that form a distinctive microscopic structure or macroscopic organ. (most glands are multicellular.)
What are some examples of multicellular glands?
*sudoriferous
*sebaceous (oil)
*salivary glands
Multicelluar glands are categorized according to two criteria-- what are they?
1) whether the ducts are branched or unbranched
2) the shape of the secretory portions of the gland
What is the difference between a simple and compound gland?
*Simple gland = unbranched duct.
*Compound gland = branched duct.
What are tubular glands?
Glands with tube like secretory parts.
What are acinar glands? (acin- = berry)
*Glands with rounded secretory portions.
*Also, termed aveolar glands.
What are tubuloacinar glands?
* Glands that have both tubular and more rounded secretory parts.
What is the structural classification scheme for multicellular exocrine glands?
I Simple glands
A. Simple tubular
B. Simple branced tubular
C. Simple coiled tubular
D. Simple acinar
E. Simple branched acinar

II Compound glands
A. Compounds tubular
B. Compound acinar
C. Compound tubuloacinar
Described simple tubular glands
*Tubular secretory part is traight and attatches to a single unbranched duct. (i.e. glands in the large intestine.)
Described simple branched tubular glands
*Tubular secretory part is branched and attaches to a single unbranched duct. (i.e. gastric glands.)
Described simple coiled tubular glands
*Tubular secretory part is coiled and attaches to a single unbranched duct. (i.e. sweat glands.)
Describe simple branched acinar glands
*Rounded secretory part is branched and attaches to a single unbranced duct (i.e. sebaceous glands)
Describe compound tubular glands
*Secretory portion is tubular and attaches to a branced duct. (i.e. bulbourethral glands)
Describe compound acinar glands
*Secretory portion is rounded and attaches to a branched duct (i.e. mammary glands)
Describe compound tubuloacinar glands
*Secretory portion is both tubular and rounded and attaches to a branched duct (i.e. acinar glands of the pancreas)
What are the three functional classifications of exocrine glands?
1) merocrine
2) apocrine
3) holocrine
What are merocrine secretions? (mero- = a part)
*Also termed eccrine
*Secretions that are sythesized on ribosomes attached to rough ER; processed, sorted and packaged by the Golgi complex; and released from the cell in secretory vesicles via exocytosis.
*Most exocrine glands of the body are merocrine glands (i.e. salivary glands and pancreas.)
How do apocrine glands secrete? (Apo- = from)
Accumulate their secretory product at the apical surface of the secreting cell. Then, that portion of the cell pinches off from the rest of the cell to release the secretion. The remaining part of the cell repairs itself and repeats the process.
* It's how mammary glands secrete.
How do holocrine glands secrete? ( holo- = entire)
The cells accumulate a secretory product in their cytosol. As the secretory cell matures, it ruptures and becomes the secretory product. The sloughed off cell is replaced by a new cell. (i.e. sebeceous gland of skin)
Connective tissue consist of two basic elements-- what are they?
1) Extracellular matrix
2) Cells
What is extracellular matrix?
* material located between its widely spaced cells.
What does extracellular matrix consist of?
*protein fibers (fribrillar)
*ground substance (interfibrillar)
*the material between the cells and the fibers.
How are extracellular fibers secreted?
*fibers are secreted by the connective tissue cells
What do the extracellular fibers actually do?
*the fibers control the surrouding watery environment via specific proteoglycan molecules.
The extracellular matrix determines much of the tissue's qualities. Give examples of some of those qualities.
In cartilage, for instance, the extracellular matrix is firm but pliable. In bone, by contrast, it is hard and inflexible.
Connective tissues vascular or avascular?
Except for cartilage, which is avascular and tendons, with a scanty blood supply, connective tissues are highly vascular.
Are connective tissues supplied with nerves?
Except for cartilage, connective tissue, like epithelia, are supplied with nerves.
What are mesenchymal cells?
*cells that give rise to the cells of connective tissue.
*also, termed mesodermal embryonic cells.
What are three examples of immature cells?
1) Fibroblast
2) Chondroblast
3) Osteoblast
(-blast = to bud or sprout)
Whare two examples of mature cells?
1) Chondrocytes
2) Osteocytes
(-cyte = mature)
State some chracteristics of fibroblast.
*large, flat cells with branching processes.
*present in all the general connective tissues(usually the most numerous)
*migrate through the connective tissue, secreting fibers and certain componenst of the ground substance of the extracellular matrix.
State some characteristics of macrophages. (macro- = large; -phage=eaters)
* have irregular shape with short branching projections and are capable of engulfing bacteria and cellular debris by phagocytosis.
*developed from monocytes, a type of with blood cell.
What are two types of macrophages?
1) fixed-- reside in a particular tissue.
2) wandering-- have the ability to move throughout the tissue and gather at sites of infection or inflammation to carry out phagocytosis.
Describe the characteristics of plasma cells
*small cells that develop from a type of white blood cell called B lymphocyte.
*secrete antibodies, proteins, that attack or neutralize foreign substances in the body
*important part of body's immune response
*reside in connective tissues
Describe the characteristics of mast cells
*are abundant alongside the blood vessels that supply connective tissue
*they produce histamine
*mast cells can kill bacteria
What does histamine do?
*chemical dilates small blood vessels as part of the infammatory response (during injury or infection)
Describe the characteristics of adipocytes.
*also called adipose or fat cells
*connective tissue cells that store triglycerides(fats)
What are some examples of white blood cells?
1)nuetrophils-- gather at sites of infection.
2)eosinophils-- migrate to sites of parasitic invasions and allergic responses.
State some characteristics of ground substance (interfibrillar extracellular matrix; inter- = between)
* the component of connective tissue between the cells and fibers.
* may be fluid, semifluid, gelatinous or calcified
* supports cells, binds them together, stores water, and provides a medium of exchange between blood and cells.
What are glycosaminoglycans (GAGs) or mucopolysaccharides?
* An assortment of large organic molecules, many which are complex combination of polysaccharides and proteins.
What do proteoglycans form?
*form the core protein and the GAGs project from the protein like the bristles of a brush.
What do GAGs actually do?
*One the most important features is they trap water, making the ground substance more jellylike.
What do adhesion proteins do? (in ground substance)
* are responsible for linking components of the ground substance to another and to the surfaces of cells.
What is the classification scheme of mature connective tissue?
A. Loose connective tissue
B. Dense connective tissue
C. Cartilage
D. Bone tissue
E. Liquid connective tissue
What is the classification scheme of loose connective tissue?
1. Areaolar connective tissue
2. Adipose tissue
3. Reticular connective tissue
What is the classification scheme of dense connective tissue?
1. Dense regular connective tissue
2. Dense irregular connective tissue
3. Elastic connective tissue
What is the classification scheme of cartilage?
1. Hyaline cartilage
2. Firbocartilage
3. Elastic cartilage
What is the classification scheme of liquid connective tissue?
1. Blood
2. Lymph
Define some characteristics of areolar connective tissue. (areol- = a small space)
*one of the most widely distruted connective tissue in the body.
*contains several types of cells, including fibroblast, macrophages, plasma cells, mast cells, and adipocytes.
* consists of three types of fibers: collagen, elastic, and reticular
* embedded in semifluid ground substance.
Where can we find areolar connective tissue?
* Subcutaneous layer deep to skin; papillary region of dermis of skin; lamina propia of mucous membranes; and around blood vessels, nerves, and body organs.
What is the function of areolar connective tissue?
* Strength, elasticy and support.
Define some characteristics of adipose tissue. (adipo- = fat)
* Consist of adipocytes(cells specialized to store triglycerides(fats) a large centrally located droplet; nucleus and cytoplasm are peripherally located.
Where can we find adipose tissue?
* subcutanous layer deep to skin; wherever areolar tissue is found.
What is the function of adipose tissue?
* reduces heat loss through skin, serves as an energy reserve, supports, and protects.
Describe some characteristics of reticular connective tissue.
* a network of interlacing reticular fibers and reticular cells.
Where can we find reticular connective tissue?
* Stroma(supporting framework) of liver, lymph nodes; red bone marrow(gives rise to blood cells), reticular lamina of the basement membrane; and around blood vessels and muscles.
What is the function of reticular connective tissue?
*Forms stroma of organs; bings together smooth muscle tissue cells; filters and removes worn-out blood cells in the spleen and microbes in lymph nodes.
Name some characteristics of dense regular connective tissue.
*estracellular matrix looks shiny white; consist mainly of collagen fibers regularly arranged in bundles; fibroblast present in rows between bundles.
Where can we find dense regular connective tissue?
* tendons (attach muscle to bone), ligaments (attach bone to bone), and aponeuroses (sheetlike tendons that attach muscle to muscle or muscle to bone).
Define some characteristics of dense irregular connective tissue.
Consist predominately of randomly arranged collagen fibers and a few fibroblast.
What is the function of dense regular connective tissue?
Provides strong attachment between various structures.
Where can we find dense irregular connective tissue?
Fascia(tissue beneath skin and around muscles and other organs), reticular (deeper) region of dermis of skin, fibrous pericardium of heart, periosteum of bone, perichondrium of cartilage, joint capsules, membrane capsules around various organs ( kidney, liver, testes, lymph nodes) and heart valves.
What is the function of dense irregular connective tissue?
Provides strength
Describe some characteristics of elastic connective tissue.
*Consist predominatly of freely branching elastic fibers *Fibroblast are present in spaces between fibers.
Where can we find elastic connective tissue?
Lung tissue, walls of elastic arteries, bronchial tubes, true vocal cords, suspensory ligament of penis, and some ligaments between vertebrae.
What is the function of elastic connective tissue?
Allows streching of various organs.
Describe some characteristics of hylaine cartilage.
* consist of a bluish-white, shiny ground substance with fine collagen fibers and many chondrocytes most abundant type of cartilage.
Where can we find hyaline cartilage?
Ends of long bones, anterior ends of ribs, nose, parts of laynx, trachea, bronchi, bronchial tubes, and emryonic and fetal skeleton.
What is the function of hyaline cartilage?
Provides smooth sufaces for movement at joints, as well as flexibility and support.
Describe some characteristics of fibrocartilage.
Consits of chonrocyts scattered among bundles of collagen fibers within the extracellular matrix.
Where can find fibrocartilage?
Pubic symphysis (point where hip bones join anteriorly), intervertebral discs (discs between vertebrae), menisci (cartilage pads) of knee, and portions of tendons that insert into cartilage.
What is the function of fibrocartilage?
Support and fusion.
What are some characteristics of elastic cartilage?
Consits of chondrocytes located in a threadlike network of elastic fibers within the extracellular matrix.
Where can we find elastic cartilage?
Lid on top of larynx(epiglottis), part of external ear(auricle) and auditory (eustachian) tubes.
What is the function of elastic cartilage?
Gives support and maintains shape.
What are some characteristics of compact bone?
consist of osteons ( osteon = harvasion system) that contain lamellae, lacunae, osteocytes, canaliculi, and central canals.
What are some characteristics of spongy bone?
*consist of thin columns called trabeculae (spaces between trabeculae filled with red bone marrow)
* Spongy bone, unlike compact bone, lack osteons.
* consist of lamellae, osteocytes, lacunue, and canaliculi.
What is the function of bone tissue?
* Support, protection, storage, houses blood-forming tissue.
* Serves as levers that act with muscle tissue to enable movement.
What are some characteristics of liquid connective tissue?
Consist of plasma and formed elements: red blood cells (erythrocytes, white blood cells (leikocytes, and platelets (thrombocytes).
Where can we find liquid connective tissue?
Withing blood vessels and withing chambers of heart.
What is the function of liquid connective tissue?
* Red bloods transport oxygen and some carbon dioxide
* White blood cells carry on phagocytosis and are involved in allergic reactions and immune system responses; platelets are essential for the clotting of blood.
What are membranes?
Flat sheets of pliable tissue that cover or line a part of the body.
What are four types of membranes?
1) Mucous membrane
2) Serous membrane
3) Cutaneous membrane (skin)
4) Synovial (joint) membrane
What does mucous mebrane or mucosa consist of?
*epithelial layer
* lamina propria (areolar connective tissue in mucous membrane)
*Muscularis mucosae(sometimes present)
What does serous membrane consist of?
*areolar C.T. covered by mesothelium.
*parietal layer
*visceral layer
*serous fluid
What is serous fluid?
a watery lubricant that allows organs to glide easily over one another or to slide against walls of cavities.
What does cutaneous membrane (skin) consist of?
*epidermis; superficial
*dermis; deeper portion.
What is the synovial membrane composed of?
*a discontinous layer of cells called synoviocytes.
* a layer of C.T (arealor and adipose) deep to synoviocytes.
* Synovial fluid(secreted by synoviocytes)
What does synovial fluid do?
lubricates and norishes the cartilage covering the bones at movable joints and contains macrophages that remove microbes and debris from the joint cavity.
What are three types of muscular tissue?
1) Skeletal
2) Cardiac
3) Smooth
Describe skeletal muscular tissue.
Long, cylindrical, striated fibers with many peripherally located nuclei; voluntary control.
Where do we find skeletal muscle tissue?
Usually attached to bones by tendons.
What is the function of skeletal muscle tissue?
Motion, posture, heat production, and protection.
Describe cardiac muscle tissue.
Branched striated fibers with one or two centrally located nuclei; contains intercalated disc; involuntary control.(Intercalated disc are unique to cardiac muscle tissue)
Where do we find cardiac muscle tissue?
Heart wall.
What is the function of cardiac muscle tissue?
Pumps blood to all parts of the body
Describe smooth muscle tissue.
Spindled-shaped (thickest in middle and tapering at both ends), nonstraited fibers with one centrally located nucleus; involuntary control.
Where do we find smooth muscle tissue?
*Iris of the eyes, walls of hollow internal structures such as blood vessels, airways to the lungs, stomach, intestines, gallbladder, urinary bladder, and uterus.
What is the function of smooth muscle tissue?
* Motion(constriction of blood vessels and airways, propulsion of foods through gastrointestinal tract, contraction of urinary bladder and gallbladder)
Describe nervous tissue.
* Consist of neurons(nerve cells) and neuroglia.
What do neurons consist of?
* a cell body and processes, known as dendrites and axons, that extend form the cell body (one to multiple dendrites and a single axon.)
Where can we find nervous tissue?
Nervous system.
What is the function of nervous tissue?
Exhibits sensitivity to various types of stimuli, converts stimuli into nerve impulses (action potentials), and conducts nerve impulses to other neurons, muscle fibers, or glands.
What is atrophy?
a decrease in the size of cells, with subsequent decrease in the size of the affected tissue or organ.