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6 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Thioamides |
MOA: Inhibits oxidation of iodide, iodination of tyrosine and coupling. Propylthiouracil/Methimazole/Carbimazole Tx Graves Disease |
Don't use Methimazole during pregnancy Methimazole more potent and cross placenta. ADR: Rash, fever, GI intolerance, joint pain |
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Iodine/Iodide |
MOA: Inhibits proteolysis of Tgb in thyroid follicle and release into bloodstream Tx: Surgical Prophylaxis, Thyroid storm, radio contrast media |
Allergic Reaction Iodism |
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Beta Blocker/Corticosteroids |
MOA: Prevent iodine from being removed from Tgb. Propanolol Prednisone (treat exophthalmos) Tx: Symptomatic relief, Thyroid Storm |
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Radioactive Iodine |
MOA: Emit radiation to destroy thyroid tissue I 131 Tx: Thyroid storm, Pre-surgical treatment of thyroid, radio contrast |
Slow acting ADR: Hypothyroidism requiring replacement therapy. Incr risk of leukemia Not to be used on females of child bearing age |
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T4 |
Tx; Creatinism, Adult Hypothyroidism, Myxoedema coma, Nontoxic Goitre |
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T3 |
Tx: Myxodema Coma |
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