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15 Cards in this Set
- Front
- Back
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Symptoms of Hyperthyroidism
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Symptoms: nervousness, irritability, poor concentration, muscle weakness, palpitations, heat intolerance, increased appetite, weight loss, diarrhea, sweating
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Physical Findings of Hyperthyroidism
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hyperkinesia, Rapid speech, fine tremor, hyperactive reflexs, lid lad, stare, (proptosis-graves), tachycardia, artrial fibrillation, moist smooth skin
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Lab findings for Hyperthyroidism
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Supressed TSH
except in secondary Hyperthyroidism Elevated T3 and T4, decreased serum cholesterol |
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DDx Hyperthyroidism
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Graves: TSH abs, high rI uptake
Gioter: Patchy rI uptake, nodules make T3/T4 Adenoma: like Goiter, 1 HOT nodule Thyroiditis: low rI uptake, release of stored hormone from damaged gland. Exogenous TH, TSH adenoma (pit) |
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Graves Disease
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Pathophys: TSHabs stim thyroid, excessT3/T4. Symetrical enlarged, increased smaller follicular cells, scant colloid, lymphocytes
Clinical findings: enlarged thyroid, wide eye stare- adrenergic tone, proptosis,orange peel skin-infiltrative dermopathy Lab Dx: low TSH, High T3/T4, TSH-ab, high diffuse rI Treatment: b-blockers, Methimazole-TPO, Radio I-ablation |
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Hyperthyroid Storm
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loss of TGB or incread in catecholamine R or catecholamines. Associated with Stress, trauma, surgery, MI, Infection.
Fever, sweating, tachycardia, a fib, deliruium, vomiting, diarrhea supportive measures, antithyroid meds (WC block), b-blockers |
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DDx Hypothyroidism
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Hashimotos: autoimmune, high TSH, low T3/T4, TGB and TPO-abs
Low I: no T3/T4 syn, Elevated, TSH Ablation: high TSH, low T3/T4 Meds: high TSH, low T3/T4 Dietary: high TSH, low T3/T4, Secondary: tumor of pit or hypo. |
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Hypothyroidism: Symptoms
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fatigue, slow thinking, lethargy, cold intolerance, weight gain, constipation, Irregualr nenses, decreased libido, muscle cramps, depression
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Hypothyroidism: Physical findings
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Round puffy face, Periobital edema, slow speech , metal clouding, Hoarseness, Hypokinesis, delayed relaxaion of tendons, bradycardia, enlarged heart, decreased CO, pericardial effusion, and ascites, cool dry skin, bittle hair
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Hypothyroidism: Lab findings
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increased TSH
decreased T3/T4 eleavated cholesterol radio I does NOT help |
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Hashimotos disease
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Pathophys: AI destruction of thyroid. TGb/TPO abs, rubby, nodular, smaller gland. destruction of follicles, infiltration
Clinical Signs: transient Hyperthyroid, hypothyroidism predom. associated with Type I diabetes, lupus, addisons Lab Dx: High TSH, Low T3/T4 abs, low rI Treat: LT4 converts to T3 in blood, need levothyroxine, increases metabolic turnover |
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Hypothyroid Emergency (myxedema coma)
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End-stage hypothyroidism.
infection, stroke, MI, in pt with hypothyroidism, Supportive measures, vent, IV LT4, CCSD, |
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Goiter
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thyroid enlargment, continuous stim of TSH (TRH)
non-toxic: TSH stim, inadquate T3/T4 syn. toxic: Gioter with hyperthyroidism compensation adquate vis inadequate |
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DDx of Goiter
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Low I
Goiterogens in diet, meds hashimotos |
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Thyroid Tumors
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nodules: benign 90%
cancer: rare, FH, radiation, hoarseness, obstuction, cold nodule Fine Needle asp Papillary, local spread-good Follicular, blood-bad Meduallary, C-cells (parafollicular) aggressive Anaplastic-very aggresive, resistant |
