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17 Cards in this Set
- Front
- Back
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Thyroid Gland secretes 3 Hormones |
Thyroxine (T4) Triiodothyronine (T3) Calcitonin |
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Parathyroid Gland (responsible for) |
Maintaining adequate Ca+ levels in the extracellular fluid |
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Hypothyroidism Deficiency in Thyroid Hormones: (Primary) |
Abnormality in the thyroid gland itself |
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Hypothyroidism Deficiency in Thyroid Hormones: (Secondary) |
Results when pituitary gland is dysfunctional and does not secrete TSH |
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Hypothyroidism Deficiency in Thyroid Hormones: (Tertiary) |
Results when the hypothalamus gland does not secret TRH,which stimulates the release of TSH |
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Hypothyroidism Youth Hormone |
Cretinism -Hyposecretion of thyroid hormone during youth
-low metabolic rate, retarded growth and sexual development, possible mental retardation |
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Hypothyroidism Adult Hormone |
Myxedema -Hyposecretion of thyroid hormone during adulthood
-Decreased metabolic rate, loss of mental & physical stamina, weight gain, loss of hair, firm edema, yellow dullness of the skin |
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Hyperthyroidism (Goiter) |
-enlarged thyroid gland - results from over stimulation by elevated levels of TSH -TSH is elevated because there is little to no thyroid hormone circulation |
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Hypothyroid Drugs |
Levothyroxine (synthetic T4) Liothyronine (synthetic T3) Liotrix (synthetic T3-T4 combined) Thyroid (desiccated animal thyroid) |
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Hypothyroid Drugs MOA |
-replace what the thyroid gland cannot produce to achieve normal thyroid levels ( euthyroid) -thyroid drugs work the same as thyroid hormones |
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Hypothyroid Indications |
-treats all three forms of hypothyroidism -Levothyroxine is preferred (it's standardized and has a predictable effect) -Euthyroid ( normal thyroid levels) -used for thyroid replacement whose thyroid gland was surgically removed or destroyed by radioactive iodine (treats thyroid cancer or hyperthyroidism) |
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Hypothroid Drugs: Adverse Effects |
Cardiac dysrthythmia Increase in beta cell receptors |
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Hyperthyroidism (excessive thyroid hormones) caused by diseases |
Grave's Disease Plummer's disease (toxic nodular) Multinodular disease Thyroid Storm (induced by stress or infection) |
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Hyperthyroidism: Affects |
-multiple body systems -overall increase in metabolism |
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Hyperthyroidism (Treatment) |
-Radioactive iodine (I 131) destroys thyroid gland -Surgically remove all/part of thyroid gland -lifelong thyroid hormone replacement - |
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Hyperthyroidism (Antithyroid drugs) |
Thioamide derivatives - Methimazole -propylthiouracil |
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Antithyroid Drugs: (Indication) |
-Used to palliative hyperthyroidism -Prevent the surge in thyroid hormones after surgical treatment during or after radioactive iodine -May cause liver and bone marrow toxicity |
