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29 Cards in this Set

  • Front
  • Back
Thyroid Gland

Located under the larynx.


2 lobes; one on each side of the trachea.


Maintains metabolism.

Thyroid Hormones

Thyroxine (T4) (Triiodonthyronine (T3))


Increases metabolism, rate of cellular respiration ( cause cells to oxidize sugars faster )


Influences growth of tissues and organs and in children.


Thyroid requires iodine in order to synthesize thyroxine.

How Thyroxine works

TRH signals the pituitary to produce TSH


TSH signals the thyroid to produce T3 & T4


Enough T3 & T4 in the blood stops TRH & TSH production. (ex. negative feedback)

Calcitonin

Regulates calcium in the bloodstream by stimulating uptake into the bones.


Can be prescribed to treat osteoporosis.


Produced in the Thyroid.

Parathyroid Glands

Four small glands attached to the thyroid.


Involved in calcium homeostasis.

Parathyroid Hormones (PTH)

Stimulates the release of calcium from the bone.


Absorbs calcium from urine. This activates Vitamin D which causes calcium to be absorbed from food.


Normal blood calcium levels inhibit the release of PTH

Goitre

Enlargement of the thyroid gland.


Caused by a lack of iodine.


Thyroxine can't be made so pituitary continues to secrete TSH, causing thyroid to swell.


Can be prevented by iodized salt.


Thyroid Disorder

Endocrine disorders

Hypothyroidism


Hyperthyroidism


Grave's Disease

Hypothyroidism

Too little thyroxine.


Symptoms - fatigue, depression, weight gain, thin brittle, dry hair and nails, cold intolerance, decreased libido.


Take thyroxine supplements.


As a child leads to cretinism (slow or little growth)

Hyperthyroidism

Too much thyroxine


Symptoms - nervousness, heat intolerance, weight loss, warm moist skin, staring gaze


Treated with medications or removal of part of the thyroid.

Grave's Disease
Severe hyperthyroidismImmune system attacks thyroidCauses swelling of the muscles around the eyes and causes them to protrude
Pancreas

Blood sugar regulation


Located behind the stomach, connected to small intestine by a duct


Final stage of digestion


Two glands: Endocrine, Exocrine

Two glands of the Pancreas

Endocrine: secretes insulin or glucagon into the blood to control sugar levels.


Exocrine: secretes digestive enzymes into the small intestine through ducts.

Islets of Langerhans
Alpha and Beta cells control blood sugar levels.
Beta cells

Produce insulin


Insulin is released as a result of an increase of glucose levels. Promotes the conversion of glucose into glycogen ( stored in the liver ) and cellular glucose absorbtion

Alpha cells

Produce glucagon


Glucagon is released as a result of a decrease in glucose levels. Promotes the conversion of glycogen into glucose

Common problems of the pancreas

Sugar diabetes or diabetes mellitus


Type 1 (juvenile onset) diabetes


Type 2 (adult onset) diabetes


Gestational diabetes


Treatments- immediate: drink sugary foods or food - long term: frequent meals or snacks

Sugar Diabetes or Diabetes Mellitus

Inadequate production of insulin


Low insulin causes too much sugar in the blood. (hyperglycaemia)


Short term: high urine volume, increased thirst, fatigue


Long term: eye, kidney, heart problems, trouble with ulcers and feeling in your extremities, glucose in urine.

Type 1 (juvenile), Type 2 (adult), Gestational

Type 1: treated by insulin replacement


Type 2: controlled by diet or oral drugs (reduce or spread out sugar)


Gestational: can develop during the late stages of pregnancy (4% of women)

Treating Diabetes

Diet


Excersize


Insulin injections


Insulin pumps


Islet cell transplants


Pills ( type II )

Hypoglycaemia

Low blood sugar


Can be caused by: too much insulin, exercise, alcohol, heat and too little food.


Short term: fatigue


Long term: unconsciousness, coma

Adrenal gland

located above the kidney


important for stress situations


2 parts: cortex (outer layer) and medulla (inner layer)

Long term stress response

Cortex releases:


Glucocorticoids - increase blood sugar


Mineralocorticoids - increase blood pressure


Gonadocorticoids - sex hormones

Glucocorticoids

Cortisol: most abundant


increases amino acids in blood, converted to sugar for energy, or used in proteins for structural repair.


Decrease swelling (anti-inflammatory)

Cortisol Control

Uses negative feedback:


Hypothalamus sends releasing hormone to anterior pituitary, pituitary releases ACTH (adrenocorticotropic hormone), adrenal glands stimulated to release cortisol, hypothalamus detects cortisol and shuts down the process.

Mineralocorticoids

Aldosterone:


Increase Na+ re-absorption in the kidney, water follows Na+ back into blood, keeps blood fluid high. (blood pressure)

Gonadocorticoids

Sex hormones supplement those produced in sex organs:


Females- converted to testosterone, accounts for pubic hair growth and increased muscle mass


Males - ???

Adrenal cortex
stimulated by the endocrine system
Adrenal medulla
Nervous system stimulatesShort term: flight or fightAdrenaline (epinephrine) and noradrenaline (norepinephrine) which increases heart and breathing rates, dilates pupils, bronchi, and surface capillaries. Similar effects to sympathetic nervous system, but lasts 10x longer