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7 Cards in this Set

  • Front
  • Back

Follicular lesion

Follicular adenoma, adenomatoid nodules, and lymphocyticthyroiditis




Lack of capsular or vascular invasion.


Resection is for definitive diagnosis and symptommanagement.


Hemithyroidectomy, no further intervention

Papillary thyroid carcinoma (PTC)

85 % of differentiated thyroid cancers


Need total thyroidectomy (except encapsulated follicular variant PTC, only lobectomy is needed) May choose to do central neck dissection (CND) – especially for larger tumors

Follicular carcinoma

– 10 % of differentiated thyroid cancers – Includes Hurthle cell carcinoma as an entity


– Need total thyroidectomy


– May choose to do central neck dissection – again, especially for larger tumors

Medullary carcinoma

– Mainstay of treatment is surgery.


– More aggressive disease.


– Total thyroidectomy and central neck lymph node dissection are imperative.


– Consider lateral neck lymph node dissection if clinical disease is present

Lymphoma

– Large, rapidly expanding neck mass.


– Portion of gland sent rather than whole gland. – Surgical resection not indicated. Attain stable airway.


– Very radio-responsive, although chemotherapy is often used.

Anaplastic thyroid cancer

– Large, rapidly expanding neck mass.


– Portion of gland sent rather than whole gland. – Invades surrounding structures.


– Surgical resection not indicated. Attain stable airway.


– Treatment is palliative or clinical trial

Thyroid nodule DDx

Benign Lesions• Nodular hyperplasia.• Colloid nodule.• Adenomatous nodules. Hashimoto’s thyroiditis.• Follicular adenoma.• Hurthle cell adenoma


Borderline (Debatable) Lesion• Hyalinizing trabecular tumor.


Malignant Lesions• Papillary thyroid carcinoma: conventional, follicular, and otherhistologic variants.• Follicular carcinoma, widely invasive.• Follicular carcinoma, minimally invasive.• Hurthle cell carcinoma, minimally invasive.• Medullary carcinoma.• Anaplastic carcinoma.• Lymphoma.• Metastasis.