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28 Cards in this Set

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Hypothyroidism Presentation
cold intolerance, fatigue, somnolence, constipation, menorrhagia, myalgias, dry skin, weight gain
Hypothyroid treatment
Levothyroxine is drug of choice - Changes are made at 6-8 week intervals
Levothyroxine counseling
Take 30 minutes before breakfast - food decreases absorption
Don't take antacids, calcium, or iron supplements withing 4 hours
Levothyroxine adverse effects
Tachycardia, angina, tremor, HA, insomnia, diarrhea, voniting, cramps, weight loss, fatigue, excessive sweating
Levothyroxine monitoring
TSH every 6-8 weeks until normalized, then every 6-12 months
Armour Thyroid Generic
Desiccated thyroid Brand
Cytomel/Triostat Generic
Liothyronine Brand (T3)
Thyrolar Generic
Liotrix (T4 and T3 in 4:1 ration) Brand
Hyperthyroidism Presentation
Heat intolerance, weight loss, weakness
Most common cause of hyperthyroidism
Graves disease, Amiodarone and iodine also
Hyperthyroidism diagnosis
Elevated T4 or T3 and decreased TSH
Hyperthyroid treatment methods
Surgery, radioactive iodine, antithyroid drugs
RAI treatment of choice in Graves' Disease
Propylthiouracil preferred in pregnancy
Thionamides (Methimazole and Propylthiouracil) MOA
Inhibit synthesis of thyroid hormones by preventing incorporation of iodine into iodotyrosines
PTU inhibits peripheral converson of T4 to T3
Methimazole and PTU Adverse Effects
Feer, headache, rash, arthralgia, jaundice, hepatitis
Hypothyroidism Presentation
cold intolerance, fatigue, somnolence, constipation, menorrhagia, myalgias, dry skin, weight gain
Hypothyroid treatment
Levothyroxine is drug of choice - Changes are made at 6-8 week intervals
Levothyroxine counseling
Take 30 minutes before breakfast - food decreases absorption
Don't take antacids, calcium, or iron supplements withing 4 hours
Levothyroxine adverse effects
Tachycardia, angina, tremor, HA, insomnia, diarrhea, voniting, cramps, weight loss, fatigue, excessive sweating
Levothyroxine monitoring
TSH every 6-8 weeks until normalized, then every 6-12 months
Armour Thyroid Generic
Desiccated thyroid Brand
Cytomel/Triostat Generic
Liothyronine Brand (T3)
Thyrolar Generic
Liotrix (T4 and T3 in 4:1 ration) Brand
Hyperthyroidism Presentation
Heat intolerance, weight loss, weakness
Most common cause of hyperthyroidism
Graves disease, Amiodarone and iodine also
Hyperthyroidism diagnosis
Elevated T4 or T3 and decreased TSH
Hyperthyroid treatment methods
Surgery, radioactive iodine, antithyroid drugs
RAI treatment of choice in Graves' Disease
Propylthiouracil preferred in pregnancy
Thionamides (Methimazole and Propylthiouracil) MOA
Inhibit synthesis of thyroid hormones by preventing incorporation of iodine into iodotyrosines
PTU inhibits peripheral converson of T4 to T3
Methimazole and PTU Adverse Effects
Feer, headache, rash, arthralgia, jaundice, hepatitis