Thomas First Aid Respiratory Pharm

Front 1

diphenhydramine mech, uses (3), toxicity (3)

Back 1

first generation H1 antagonist

uses: allergies, motion sickness, sleep aid

sedation, antimuscarinic, anti aplha-adrenergic

Front 2

chlorpheniramine mech, uses, toxicity (3)

Back 2

first generation H1 antagonist

uses: allergies, sleep aid, motion sickness

toxicity: sedation, antimuscarinic, anti alpha-adrenergic

Front 3

dimenhydrinate mech, uses, toxicity (3)

Back 3

First generation H1 antagonist

uses: sleep aid, motion sickness, allergies

toxicity: sedation, antimusarinic, anti-alpha adrenergic

Front 4

Loratadine mech, use

Back 4

2nd generation H1 antagonist

use all second generations for allergies

less CNS penetration than 1st generation (less sedation)

Front 5

Fexofenadine mech

Back 5

2nd generation H1 antagonist

less CNS penetration than 1st generation

Front 6

desloratadine mech

Back 6

2nd generation H1 antagonist

Front 7

cetirizine

Back 7

2nd generation H1 antagonist

Front 8

Isoproterenol
mech, use, toxicity

Back 8

non selective beta agonist
asthma
adverse effect = tachycardia

Front 9

Albuterol mech

Back 9

beta 2 agonist

Front 10

salmeterol mech, toxicities (2)

Back 10

long acting beta 2 agonist

adverse effects = tremor, arrhythmia

Front 11

Theophylline mech, use, toxicities (3)

Back 11

increases cAMP

asthma

toxicities bad = cardiotoxic, neurotoxic, drug interactions (metabolized by p450)

Front 12

Ipratropium mech, uses

Back 12

competitive muscarinic blocker

(for asthma and COPD)

Front 13

Cromolyn mech, use

Back 13

stabilizes mast cells
prophylaxis for asthma, DOES NOT work for acute attack

Front 14

what is mech of bethomeclasone and prednisone on working for asthma

Back 14

inhibit NF-kappaB that decreases production of TNF-alpha

Front 15

Zileuton mech, use

Back 15

blocks conversion of arachadonic acid to leukotrienes

asthma

Front 16

Zafirlukast mech, use

Back 16

block leukotriene receptors

aspirin-induced asthma

Front 17

Montelukast mech, use

Back 17

block leukotriene receptors

aspirin-induced asthma

Front 18

Guaifenesin use

Back 18

removes excess sputum without supressing cough reflex

Front 19

Bosentan mech, use

Back 19

compeititvely inhibits endothelin-1

used for pulmonary HTN