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161 Cards in this Set

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What are the 3 overall functions of males?
1) Produce and maintain supply of sperm (spermatogenesis)
2) Detect females in estrus
-pheromones, visual
3) Inseminate females and fertilize the female gamete
The testes are suspended by the _________ and _______.
Spermatic chord and cremaster muscle
What 2 parts of the brain hormonally control the secretory pathway of the male reproductive system?
Hypothalamus
Anterior pituitary
What is the function of the testis with seminiferous tubules?
sperm production
What is the function of the collecting ducts (site of production to epididymis) in the male reproductive system?
Transport and storage of sperm
What is the function of the epididymis?
Transportation, maturation and ejaculation
-where sperm is stored and matures
What is the function of the vas deferens (sperm duct)?
transport and ejaculation
-transports sperm from testes to be released
What is the function of seminal vesicles?
Secrete a thick liquid to transport the sperm
What is the function of the prostate gland?
Secretes think alkaline solution to neutralize urine and the female system
What is the function of the bulbourethral gland (Cowper's gland)?
Secretions may lubricate, flush out urine, or form a gelatinous plug
What is the function of the urethra?
Allows passage for urine & sperm
What is the function of the penis?
Copulation
True or false. Testicular volume directly correlates to the fertility of each specie
False
What cells comprise the testicular parenchyma?
Sertoli cels and Leydig cells
What is the function of Sertoli cells?
Involved in control of spermatozoa development
What is the function of Leydig cells?
Stimulated by LH, produce testosterone
How do spermatozoa move through the seminferous tubules?
Myoid cells contract (mechanical) to move sperm from the seminiferous tubules to the rete-testis
What is the function of the Rete-testis?
Function in sperm transport from the seminiferous tubules
How does sperm move through the efferent duct to arrive in the epididymis?
Water absorption occurs causing sperm to be drawn towards the epididymis
When are sperm capable of fertilization?
After maturing and being stored in the epididymis
Explain the 6 anatomical sites of sperm production/transport before arriving at the pelvic urethra.
1. Testicular parenchyma
-sertolic & leydig cells
2. Seminiferous tubules
3. Rete-testis
4. Efferent ducts
5. Epididymis (head to tail)
6. Vas deferens
What are the 5 structures contained in the spermatic cord?
1) Vas deferens
2) Pampiniform plexus
3) External cremaster muscle
4) Nerves
5) Lymphatic vessels
What do you call the connective tissue that holds the testis together?
Tunica albuginea
What is the medical term for the head and tail of the epididymis?
Head: caput epididymis
Tail: Cauda epididymis
What are the 5 stages of sperm development?
1. spermatogonia (diploid) -----> mitosis ----->
2. primary spermatocyte -----> meiosis I ----->
3. 2 secondary spermatocytes---> meiosis II
4. 2 non-motile spermatids ----> elongate & develop flagella-->
5. Sperm
Where are myoid cells located in the seminiferous tubules?
In the basal compartment
True or false. After reaching sexual maturity males can continuously produce sperm.
True, because the spermatogonia are constantly replacing themselves by undergoing mitosis
What is the pampiniform plexus? Function
-A single artery surrounded by a network of veins (increased SA)
-Counter-current heat exchange causes a cooling f arterial blood supply
What are the 2 ways that the blood supply to the testis is cooled?
1. Pampiniform plexus
2. Convoluted testicular artery on the surface of the testis
What 3 anatomical structures of the male reproductive system are involved in thermoregulation of the testes?
1. Scrotum
2. Tunica albuginea
3. Spermatic cord
-brings testes closer or farther from body
What is responsible for testicular decent during early development?
Gubernaculum testis
What 3 structures are formed after the gubernaculum shrinks and degenerates?
1. proper ligament of the testis
2. ligament of the tail of the epididymis
3. scrotal ligament
What does the proper ligament of the testis connect?
tail of the epididymis to the testicle
What does the ligament of the tail of the epididymis connect?
Tail of the epididymis to the scrotum (proximal to the vaginal tunic)
What does the scrotal ligament connect?
Vaginal tunic to the scrotum
What are ampullae?
Dilation of the terminal part of the vas deferens due to glandular thickening of the wall
What is the function of ampullae?
Extra-gonadal sperm storage
-can get plugged & cause issues w/ ejaculation
What are the seminal vesicles?
Paired sacculated pouches and gland that joins the ductus deferens to form the ejaculatory duct.
What is the function of the seminal vesicles?
Provides ejaculate with milky and highly viscous fluid
Where is the prostate located?
Surrounds the neck of the bladder and urethra
What is contained in the seminal fluid excreted by the prostate gland?
Acid phosphates and proteolytic enzymes that clean the urethra during ejaculation (alkaline)
Describe the structure of the prostate gland in bucks, dogs, stallions, rams, bulls and boars.
Diffuse: Rams & bucks
Lobed: dog & stallion
Combination: bulls & boars
Where is the bulbourethral gland located?
On either side of the urethra
What animal does not have a bulbourethral gland?
Dog
The Bulbourethral gland is enlarged in the _______ and is known as the bulbocavernosus bland.
Boar
What is the function of Cowper's gland (bulbourethral gland)?
Alkaline pH neutralizes the urethra
What animal(s) has the testes oriented vertically with the cauda down?
Ruminant
What animal(s) has the testes oriented horizontally?
Stallion & dog
What animal(s) has the testes oriented perineal with the cauda up?
Boar, tom, camelid
What animal(s) have ampullae?
Ruminant & stallion
What animal(s) have seminal vesicles?
Ruminant
Stallion
Boar
What animal(s) have a prostate gland?
All of them
Ruminant, stallion, boar, dog, camelid, tom
What animal(s) have a fibroelastic sigmoid penis type?
Ruminant
Boar
Camelid
What animal(s) have a vascular penis type?
Stallion
Dog
Tom
Where do ruminants deposit semen?
vagina
Where
Where do stallions deposit semen?
Uterus
Why do boars form a mucus plug after ejaculating into the female?
Because they deposit the semen in the cervix so the plug keeps the sperm from falling out.
Where do dogs deposit semen?
Vagina
Where do toms deposit semen?
Vagina
Where do camelids deposit semen?
Uterus
What accessory glands can be examined during a physical exam on a bull?
Seminal vesicles (lobular)
Prostate (wedding ring)
Ampullae
True or false. Bulbourethral glands can be examined during a physical exam of a bull.
False, have to use an ultrasound
How do bulls elongate their penis?
Fibroelastic sigmoid penis, doesn't allow for engorgement so when it gets full of blood the sigmoid straightens out
True or false. A hard and smooth seminal vesicle in a bull could be abnormal.
True, should be spongy and lobular
Where do the ampullae drain?
into the pelvic urethra
_______ is the site in the bull where all the accessory sex glands empty.
Colliculus seminalis
What are the 6 anatomical components of the penis?
1. Cavernous bodies
-corpus spongiosum
-corpus cavernosum
2. Tunica albuginea penis
3. Sigmoid flexure
-boar, ruminants, camelid
4. Retractor penis mm. (paired)
5. Glandis penis
6. Sheath & prepuce
-tissue that covers & protects the penis
Where is the corpus spongiosum located? Corpus cavernosum?
Corpus spongiosum: surrounds urethra
Corpus cavernosum: above corpus spongiosum
What animal(s) have a tunica albuginea penis?
Boar, ruminants, camelids
What muscle is responsible for maintaining an erection?
Corpus cavernosum penis
What is the medical term for the free end of the penis?
Glandis penis
What animals have retractor penis muscles?
Boar, ruminants, camelids, stallion
What is the function of the retractor penis muscle?
Relaxes to extend the penis or contracts to draw the penis into the body
Where does the penis technically begin & end?
Begins when the urethra leaves the pelvis, with the external urethral orifice at the free end of the penis (glandis penis)
How is the penis of a stallion very different from that of a boar, ruminant and camelid?
Stallions have a large amount of erectile tissue compared to the other 3 animals mentioned which have small amount of erectile tissue
The _______ is homologous to the clitoris in the female.
Glans penis
What are 2 anatomical components of the penis unique to the dog?
Os penis
Bulbus glandis
What is unique about the boar's penis?
Has a counter spiral configuration (cork screw) of the glandis penis & has a preputial diverticulum (accumulates fluid for lubrication during intromission)
What is unique about the penis of bucks and rams?
have a urethral process (2-3 cm extension of the urethra)
What are 2 anatomical components of the penis unique to the dog?
Os penis
Bulbus glandis (area of penis that becomes more engorged than the rest)
At what age can bucks and rams perform fertile mating? Why?
By 4-5 months because the natural adhesion of the urethral process and glans penis to the prepuce begins to separate at 3 mo
What is unique about the boar's penis?
Has a counter spiral configuration (cork screw) of the glandis penis & has a preputial diverticulum (accumulates fluid for lubrication during intromission)
What is unique about the penis of bucks and rams?
have a urethral process (2-3 cm extension of the urethra)
At what age can bucks and rams perform fertile mating? Why?
By 4-5 months because the natural adhesion of the urethral process and glans penis to the prepuce begins to separate at 3 mo
What is unique about the ejaculation in bulls?
The end of the penis spirals at ejaculation
What is unique about the anatomy of the stallion penis?
Has a urethral sinus and fossa glandis
-where bean accumulates (smegma)
Where is the fossa glandis and urethral sinus located on the stallion penis?
At the tip of the penis dorsal to the urethra
What is unique about the anatomy of a camelid's penis?
The tip of the penis looks like a hook - allows them to direct the urine stream backwards between the legs
A camelids penis hooks backward and this is what allows them to pee backwards between their legs. So how do camelids mate?
The protractor preputial muscles pulls the prepuce forward before mating, changing the direction of the opening and allowing the penis to be directed forward.
What is unique about a camelids penis at birth?
The penis is completely adhered to the prepuce until testosterone influence causes the adherence to gradually disappear as the male matures.
What is unique about the male anatomy of toms?
Have a small os penis and cornified papillae on the end of the penis ("spikes")- may have a stimulus effect on ovulation of the queen
What is different about the anatomy of the penis in cervids?
Some cervids do not have a sigmoid flexure and an increase in diameter is not observed by up to a 40% increase in length is
-penis is more elastic than ruminants
What direction does the urethral opening of cervids face?
Dorsally--> thrash urination
How can you grossly determine if a cat is neutered?
Look to see if penis has spikes, the spikes develop under the influence of testosterone so if no barbs= castrated (take a few weeks to regress)
What is the name of the axis that controls the behavior and external phenotype of male animals?
Hypothalamic-pituitary-testicular axis
What hormones are secreted by each component in the hypothalamus-pituitary-testicular axis?
Hypothalamus: GnRH (gonadotropin-releasing hormone)
Pituitary: FSH & LH
Testicles: testosterone, inhibin, androgen-binding protein
What is the source of FSH and LH? What type of tissue secretes the hormones?
Anterior pituitary-glandular tissue
What type of cells secrete oxytocin and vasopressin in the posterior pituitary?
Nerve cells (neurohypophysis)
What is the function of GnRH released from the hypothalamus?
stimulates release of LH & FSH from the pituitary gland (apophysis)
What is the function of FSH in males?
Regulates spermatogenesis and production of ABPs by the Sertoli cells
What is the function of LH in males?
Stimulates testosterone production by Leydig cells
Why does oxytocin also have behavioral changes associated with it?
Because released by nerve cells in the neurohypophysis.
What hormones are secreted by the interstitial cells (Leydig cells) of the testes?
Androgen production (testosterone), generation of haploid germ cells
What hormones are secreted by the Sertoli cells of the testes?
-Inhibin (inhibits FSH secretion)
-Provide nourishment to the developing germ cells
What is the function of FSH in males?
Regulates spermatogenesis and production of ABPs by the Sertoli cells
What is the function of LH in males?
Stimulates testosterone production by Leydig cells
Why does oxytocin also have behavioral changes associated with it?
Because released by nerve cells in the neurohypophysis.
What hormones are secreted by the interstitial cells (Leydig cells) of the testes?
Androgen production (testosterone), generation of haploid germ cells
What hormones are secreted by the Sertoli cells of the testes?
-Inhibin (inhibits FSH secretion)
-Provide nourishment to the developing germ cells
What cells are responsible for the blood-testicular barrier?
Sertoli cells
What is the function of testosterone in the male (4)?
1) Mating behavior (libido)
2) Spermatogenesis
3) Spermacytogenesis
4) Maintenance of male duct system
What is the function of inhibin in the male?
Regulates release of FSH
What is the function of androgen binding protein (ABP)?
Maintains high concentration of testosterone in the seminiferous tubules
-grabs testosterone and keeps in testis
What is the function of estrogen in males?
Mating behavior
What is the function of prostaglandin (PGE) in males?
Semen transport (main one)
Some changes in behavior
What produces ABP?
Sertoli cells in seminiferous tubules
Why is it so important for ABP to maintain high testosterone concentrations in the seminiferous tubule?
High testosterone and DHT enable spermatogenesis in the seminiferous tubules and sperm maturation in the epididymis
What regulates ABP production?
FSH influence on sertoli cell, testosterone, insulin and retinol (Vit A1)
What 3 things are stimulated by testosterone?
1) Secondary sex characteristics
2) Muscle development
3) Accessory glands
Testosterone maintains the function of the male reproductive tract and the ______ muscles.
Penis muscles for ejaculation
What hormone maintains the male libido?
Testosterone
What is inhibin?
a peptide hormone secreted by the Sertoli cells that inhibits FSH secretion by the anterior pituitary
When is estrogen most apparent in blood and urine of males?
During puberty and old age
What is spermatogenesis?
Spermacytogenesis + spermiogenesis
-formation and development of spermatozoa by meiosis
What is spermacytogenesis?
First stage of spermatogenesis. Spermatogonia develop into spermatocytes then to spermatids (still round cells).
What is spermiogenesis?
Second stage of spermatogensis. Transformation of spermatid into a spermatozoon
-Round cell to slender sperm
What is release of the spermatozoa from the sertoli cells into the lumen of the seminiferous tubules called?
Spermiation
What is the hormone control of mitosis & meiosis I in spermatogensis?
No hormonal control
What is the hormonal control of Meiosis II during spermatogenesis?
Testosterone
What is the hormonal control of spermiogenesis?
FSH +/- testosterone
What role do LH and FSH play in hormonal control of spermatogensis?
LH: cause interstitial cells to produce testosterone
FSH: cause sertoli cells to produce ABP & inhibin
What role do ABP & inhibin play in hormonal control of spermatogenesis?
ABP: maintains testosterone levels for meiosis and spermiogenesis.
Inhibin: keeps FSH levels in balance
Why does sperm production begin at puberty?
That's when levels of testosterone are sufficient for sperm production
What is the definition of puberty?
Point at which an individual develops sexual activity and produce enough sperm to impregnate a female
What are 7 factors that affect the time of puberty onset?
1) Physical environemnt
2) Age
3) Breed
4) Sire
5) Dam
6) Temperature
7) Photoperiod
Onset of puberty is often more closely related to _______ and _____ than age!
Nutrition and BW
It is not uncommon in _____ and _____ for the testis to descend late.
Boars (3.5-4 months)
Stallions (may take 1-2 years)
What is the only animal that have descended testes at birth and just continue to grow?
Llama
In most domestic species (not boar or stallion) the testes descend through the internal inguinal ring by ______ time after birth is necessary for a final scrotal position.
2 weeks
When should a stallions testes descend?
By 16 months, even though considered abnormal some take 2 years
When should a dogs testicles be descended?
By 5 weeks of age and palpable by 6-8 weeks (not considered cryptorchid til 6 mo-1 year)
What are the 4 general steps to developing an erection?
1) Parasympathetic response
2) Corpus cavernosum fills with blood
3) Ischiocavernosus muscle pumps blood
4) Rigidity increase to aid intromission
What increases during erection of a fibroelastic penis?
Little change in size, but large increase in blood pressure
What increases during erection of a musculocavernosus penis?
Increase in both length and diameter
What part of the ANS controls ejaculation?
Both sympathetic and parasympathetic
-emission (sympathetic) & propulsion (parasympathetic)
What are the 2 components of semen?
Seminal plasma + spermatozoa
What are the 3 fractions to an ejaculate? What are produces and what are the characteristics of each fraction?
1) Pre-sperm ---> from urethral glands & seminal vesicles (1st set of glands), low sperm #
2) Sperm rich--> epididymal, ampulla & prostate, high sperm #, large volume
3) Post-sperm--> gel from Cowper's glands & prostate
-helps fix pH within male & female repro tracts
What are the 3 fates of unejaculated sperm?
1) Resorbed by excurrent duct system
-epididymis, vas deferens and ampulla; some selective removal of abnormal sperm (macs)
2) Sperm lost in urine
3) Masturbation loss of sperm
-management problem in boars & stallions
What domestic species have seasonal semen quality?
Ram, buck
(+/-): Stallion, boar, camelid
What stimulates melatonin secretion? What is the source of melatonin?
Secreted from pineal gland during hours of no light
-increase during short days and decrease during long days associated with transition into breeding season
What animals estrus cycles are affected by melatonin levels?
Small ruminants (buck & ram)
horses
How can melatonin suppress the labido in mammals that have a breeding season when daylight hours are long?
Inhibiting secretion of LH & FSH from the pituitary gland
-short day breeders are stimulated by melatonin
Physiologic changes like testicular behavior and semen quality in rams is due to what? What modulates this?
Activation of the hypothalamus and changes in effectiveness of testosterone on the negative inhibition of GnRH
-modulated by increasing periods of darkness (usually fall)
There is some controvery about whether the buck is truly a seasonal breeder, but why are they considered short day breeders?
LH and testosterone concentrations peak in the fall
Seasons don't tend to infect camelid breeding very much, what seems to have a bigger effect on the male libido?
Male exposure to females: decreased libido if exposed to females for extended periods of time, but decreased levels of testosterone w/o female exposure
When is the concentration of sperm greatest in cervids? What is the most marked change in cervids during breeding season?
Greatest sperm volume in autumn, scrotal difference has been noted to 3x at onset of rut
Why is testosterone important in cervids for reasons other than breeding?
Antlers cycle with the rut, need testosterone to shed the velvet on the antlers, if don't shed velvet then can get infection
There is some controvery about whether the buck is truly a seasonal breeder, but why are they considered short day breeders?
LH and testosterone concentrations peak in the fall
Seasons don't tend to infect camelid breeding very much, what seems to have a bigger effect on the male libido?
Male exposure to females: decreased libido if exposed to females for extended periods of time, but decreased levels of testosterone w/o female exposure
When is the concentration of sperm greatest in cervids? What is the most marked change in cervids during breeding season?
Greatest sperm volume in autumn, scrotal difference has been noted to 3x at onset of rut
Why is testosterone important in cervids for reasons other than breeding?
Antlers cycle with the rut, need testosterone to shed the velvet on the antlers, if don't shed velvet then can get infection