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53 Cards in this Set
- Front
- Back
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what type of lesion is FLAT RED LESION
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macule
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what type of lesion is RED RAISED LESION
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papule
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what type of lesion is RAISED LESION IN DERMIS AND HYPODERMIS
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nodule "feel something moving inside"
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what type of lesion is RAISED PLATEAU LIKE LESION MORE THAN 1 CM IN DIAMETER
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plaque
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what type of lesion is "BLISTER" FLUID FILLED LESION ON SUPERFICIAL SKIN LAYER
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vesicle (<.5cm)
bullaeu (>.5cm) |
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what type of lesion is RAISED LESION W/ SURROUNDING ERYTHEMA
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wheal
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how are majority of dermatoligic drug reactions managed
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corticosteroids
antihistamines |
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what is the most common manifestation of drug induced reactions
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maculopapular erruptions
immunological |
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what are the properties of urticaria
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no scarring
pruiritus IgE antibodies, histamine release |
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what are the primary factors of acne vulgaris
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increased sebum production
slaughing of keratinocytes bacterial growth inflammation |
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how does increased sebum production occur
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due to increased sensitivity to androgens during puberty
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what does abnormal keratinization of follucular epithelium lead to
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sloghing of keratinocytes and sebum plugs up follicle leading to Comedo formation which is a favorable environment for P. acnes growth
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what happens w/ the Growth of P. acnes
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this causes a immune response which causes release of inflammatory cytokines
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what happens in inflammation
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results in papule or pustule formation
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what drugs are given to decrease sebum production
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isotretinoin
hormone therapy |
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what drugs are given to normalize follicular keratinization
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BPO
azelaic acid retinoids |
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what drugs are given to suppress bacterial growth
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antibiotics
BPO isotretinoin azelaic acid |
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what drugs are given to prevent inflammatory response
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isotretinoin
oral antibiotics spironolactone retinoids BPO |
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what is a closed comedones and a open comedones
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closed = white head
open = black head noninflammatory lesions |
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what severity of acne is this NONINFLAMMATORY LESIONS, NO SCARRING
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mild
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what severity of acne is this INFLMMATORY AND NONINFLAMMATORY LESIONS POSSIBLE SCARRING
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moderat
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what severity of acne is this MANY INFLAMMATORY LESIONS AND SOME NONINFLAMMATORY LESIONS, EXTENSIVE SCARRING
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severe
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what is used to treat mild acne
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retinoids +/- azelaic acid, topical antimicrobial, salicylic acid
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what is used to treat moderate acne
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retinoids +/- BPO
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what is used to treat severe acne
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isotrinoin
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what is the 1st line drug for mild/moderate inflammatory acne and comedonal acne
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retinoids, use w/ topical antibiotics or BPO
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tretinoin
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retinoid
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adapalen
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retinoid
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tazarotene
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retinoid, 1st line topical for psoriasis, 2nd line systemic for psoriasis
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what are the topical antibiotics for acne
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erythromycin
clindamycin |
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what are the systemic antibiotics for acne
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tertracyclines
macrolides |
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what is used in systemic treatment of acne via hormonal therapy
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estrogen (inhib androgen production)
oral contraceptives (increase sex binding protein to bind testosterone therefore less stimulation of sebaceous gland and also inhibits ovarian production of androgen) antiandrogens (inhibit 5 alpha reductase therefore less sebum production) |
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what is also used to treat hirsutisim
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antiandrogens (spironolactone/drosperinone[yasmin])
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what is the 1st line for severe nodular acne
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isotrinoin
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what are the properties of isotrinoin
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covers all causative factors of acne
teratogenic preg cat X I pledge program |
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what infection is defined by chronic inflammatory skin disorder and silver white scales
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psoriasis
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what is the list of treatment options from mild to severe psoriasis
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emolients
tazarotene/steroids vit D analogs coal tar/anthralin UVB phototherapy PUVA oral retinoids: cyclosporine, methotrexate biologicals |
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what are the topical 1st line therapy for psoriasis
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corticosteroids
vit D analog tazarotene |
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what are the topical 2nd line therapy for psoriasis
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coal tar
anthralin topical calcineurin inhibitors (pimecroLIMUS, tacroLIMUS) |
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what are the systemic therapy drugs 1st line in psoriasis
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biological therapy
TNF alpha inhib (infliximab, entanercept, adalimuxmab) T cell activation inhibitors (alefacept, efalizumab) |
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what are the systemic 2nd line drugs for psoriasis
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cyclosporine
methotrexate acitretin tazarotens tacroLIMUS/pimercroLIMUS |
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what is used in Psoriasis phototherapy
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PUVA (psoralen + UVA)
psoralen |
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what is the therapy for Atopic dermatitis
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corticosteroids
topical calcineurin inhibitors |
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what are the diagnostic criteria for Atopic dermatitis
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itchy skin and 3 of the following:
history of dry skin over past year history of hay fever/asthma rash before 2yrs old flexural exema flexural dermatitis |
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tinea pedis
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dermatophyte
athletes foot |
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tinea cruris
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dermatophyte
jock itch |
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tinea corpuris
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dermatophyte
ring worm |
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tinea barnace
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dermatophyte
beard/mustache |
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tinea cupitis
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dermatophyte
scalp |
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tinea unguium/onychomycosis
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dermatophyte
nail plate/bed |
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tinea versicolor
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yeast
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what can be used to treat tinea onychomycosis
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ciclopirox
terbinafine itraconazole fluconazole |
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what can be used to treat tinea versicolor
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topical: imidazole
systemic: ketoconozole, miconozole, oxiconozole, sulconazole, clotrimazole, econazole |
