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17 Cards in this Set
- Front
- Back
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What are the positive Symptoms of schizophrenia?
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auditory hallucinations
delusions |
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What are the Negative Symptoms of schizophrenia?
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lack of motivaiton
lack of emotion poor self care reduced speech output attention impairment |
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How is schizophrenia diagnosed (American Psychiatric Ass.)
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Patients with 2 or more of the following:
- delusions - hallucinations - disorganised speech - catatonic behaviour - negative symptoms |
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What are the typical antipsychotics
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• Phenothiazines: chlorpromazine, thiodazine, fluphenazine, trifluoperazine
• Butyrophenones: haloperidol, benperidol • Thioxanthenes: flupentixol • Benzamides: amisulpride |
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What are the atypical antipsychotics
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• Clozapine
• Risperidone • Olazapine • Quetiapine |
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What was a traditional treatment for acute schizophrenia
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• Chlorpromazine po
• Thioridazine po • Trifluoperazine po • Haloperidole im or iv |
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What drug may be given to counter extrapyramidal effects of haloperidole?
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Benztropine po or iv
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What do more recent guidelines recommend for acute schizophrenia?
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• Risperidone po
• Quetiapine • Olanzapine |
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When should an atypical changed?
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- no effect after 6-7 weeks
- unacceptable side effects |
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What drugs are given in relapse prevention of schizophrenia to patients with GOOD compliance?
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Trifluoperazine po
Haloperidol po Thioridazine po Risperidone po |
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What drugs are given in relapse prevention of schizophrenia to patients with POOR compliance?
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Depot agent:
Flupentixol decanoate Haloperidol decanoate Fluphenzine decanoate Injectable risperidone or olanzapine |
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What are cons associated with depot agents?
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- may take several months to reach steady state
- Not always consistent plasma drug level - variable side-effects - extrapyramidal effects common |
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Where is depot agent injected?
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deep, upper, outer quadrant of buttock
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What is a summary of the major side effects of antyipsychotics?
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• Extrapyramidal: dystonia, Parkinson-like side effects, tardive dyskinesia
• Postural Hypotension • Photosensitivity • Sedation • Anticholinergic |
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Which antipsychotic may cause sunburn?
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Chlorpromazine
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Which antipsychotic is associated with a reduction in visual acuity and impairment of night vision?
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Thioridazine
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Which antipsychotic is particularly associated with dystonic reactions and akathisia?
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Haloperidol
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