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69 Cards in this Set

  • Front
  • Back
4 characteristics that can be found in xerosis
Roughness, scaling
Loss of flexibility
Inflammation and/or fissures
Pruritis
most common affected areas of xerosis (4)
lower legs, forearms, dorsa of hands, and the back
Dry Skin - Etiology (5)
lack of water in stratum corneum (causes abnormal loss of cells in stratum corneum.)
winter itch
Low humidity environments

Excessive use of detergent, soap, and hot water (soap removes natural oils increasing dryness)

Physical damage to stratum corneum (shaving, scrubbing)
chapping occurs if water in skin is at what lvls
<10%
increased incidence of dry skin in what pop

why? (2)
elderly

due to Epidermal thinning
resulting from abnormal maturation of keratinocytes
Hormonal changes reduce sebum production
systemic disorders causing dry skin (2)
Dehydration
Hypothyroidism
key to treatment approach for dry skin
Improve and maintain skin hydration
`
3 ways to treat dry skin (non pharm)
Reduce exposure to aggravating factors
Maintain barrier (skin hydration via moisturizers)
Avoid products containing alcohol or keratolytics
4 aggravating factors of dry skin
Hot water
Cold air/wind
Low humidity in winter (makes skin less flexible = bracks)
Sun
Soaps and detergents
3 skin product types
Bath products
skin cleansers
moisturizers
Bath oils- properties
lubricating but NON occlusive
Colloidal oatmeal products properties (2)
soothing
anti itch
Bath soaps (2 types)
Oilated soaps
Glycerin soaps
Available bath oils include (4)
Lubriderm
neutrogena
nivea
generics
bath oil contents (2)
mineral or vegetable oil with a surfactant
bath oil conc and temperature correlate with what?
Adsorption onto and absorption into the skin increase with oil concentration and temperature
benefit of bath oils
provide lubrication to the skin
main limitation of bath oil

how to get around it (2)
often diluted in bath water

Add in at end of bath, “pat” skin dry
Wet compresses may be used, body oils also available
4 pt edu points with bath oils
Use with caution: oils may make tub slippery
May increase difficulty with cleansing skin
All bath oils appear equally useful
Patients with additional dermatological conditions should avoid fragrances
Colloidal Oatmeal Products- contain what 3 things
Contain starch, protein, and oil
efficacy/evidence for colloidal oatmeals (2)
Appear to be less effective for dry skin than bath oils

Evidence-based efficacy is minimal
oatmeal beneficial effects (3)
Lubricating effect
-Colloidal oatmeals combine effect of oatmeal and bath oils. (soothing, anti itch)
what is in a bath soap (3)
salts of long chain fatty acids and alkali metal (Na+, K+)

fats/oils too
bath soaps + water- what does it do

downside to this
With water, they act as surfactants to remove unwanted substances from skin
Necessary lipids also removed
what about extra oil soaps, to offset the stripping effect of natural body oils? and prevent drying?
usually lather and clean poorly.
Dry skin- what soap to choose
sensitive skin?
Mild soaps with added fats or oils

Balance oils, avoid deodorant and antibacterial soaps
favorable bar soaps to use (3)
Unscented Dove®, Basis®, Oil of Olay® Sensitive Skin, Glycerin soaps
Glycerin soaps- evidence?
properties (3)
Water-soluble, higher oil content, neutral pH

no evidence really
what to rec if soaps should be avoided?
Soap-free Skin Cleansers
contents of soap free skin cleansures (2)
contain a surfactant and oil
how soap free cleansers work (2)

evidence?
Foam upon application and leave a thin lipid layer on skin when removed gently
Assists in retaining water in stratum corneum

Low potential for irritation, but clear evidence of superiority is lacking
soap free skin cleansers (5)
Aveeno® Cleansing - Cetaphil®
- pHisoDerm® - Neutrogena®
- Free & Clear®
cleanser good for infants
soap free skin cleansers
best way to use soap free cleansers (2)
Apply to skin and rub gently
rinse and pat skin dry
Apply, rub gently, and remove excess with soft cloth to leave thin film on skin
most moisturizers and dry skin products contain a combination of what 3 things?
Emollients/moisturizers
Humectants
Keratin-softening agents
agents that enhance stability and appearance in moistureizers (4)
Emulsifiers (span, tween)
Emulsion stabilizers aka thickening agents (methylcellulose)
preservative
Fragrance or color can also be added
Moisturizers/Emollients definition
Occlusive agents used to prevent or relieve signs and symptoms of dry skin
primary actions of moisturizers/emoolients (4)
leave oily film on skin surface so that moisture cannot escape

Re-establishes integrity of stratum corneum
Lipid components reduce flaking
Improve skin tone, texture
how does moisturizers decrease flaking
Reduces flaking by flattening scales against skin
-
application of lotions after handwashing
May need to apply 3-4 times/day and on hands after each washing for max benefit
4 examples of emollients
petrolatum, lanolin, mineral oil, and butyl stearate
emollients- what are they doing
Fill spaces between skin cells and replace lipids
petrolatum- when to avoid
use
avoided on puncture wounds and infections as can cause more inflammation
effective occlusive agent and skin protectant (better than others)
Lanolin- may cause what AE
allergic rxn (from sheep)
ointments are hard to apply- counseling tips (2)
Recommend warming product, applying thin layer and massage gently
Humectants- used to do what
Used to draw water into the stratum corneum from dermis or high humidity atmosphere (>80%)
Common hydrating agents (humectants) (4)
Glycerin
Propylene glycol
Phospholipids (often contain lecithin)
Alpha-hydroxy and lactic acids also considered
glycerin- humectant- mechanism

what conc. of glycerin solutions do we use. why?
Speeds diffusion of moisture from dermis to epidermis
Use low concentrations (5%) to decrease water loss
propylene glycol downside
May cause irritation with increasing concentrations
phospholipid humectant mechanism
Contain lecithin; may form a complex with water and form fatty acids (via hydrolysis) to help retain moisture
Keratin-Softening Agents do what 2 things
Promotion of hydration & break down of scales or crusts by binding to skin proteins
Keratin-Softening Agents (2)
Urea (carbamide)
Lactic Acid
Allantoin
Urea- properties (3)
Mildly keratolytic, may remove scales and crusts

Promotes hydration by increasing water uptake in the stratum corneum

Affects elasticity of stratum corneum
avail % formulations of urea- and when to use (like, the severity of dry skin) (3)
Mild conditions: 10%
Resistant skin: 20-30%
Carmol® 40: RX strength (40% urea)
Alpha-hydroxy acids properties- it is used as what? )2_

mechanism

it's an acid so what about the pH?
keratin softening and Increase skin hydration (humectant properties)

May act as modulator of keratinization rather than as a keratolytic

May be neutralized in formulation? to achieve favorable pH
allantoin products (2)
Sofenol 5®, Cutemol
allantoin efficacy and mechanism
Thought to soften keratin by disrupting its structure

Less effective as softening agent than urea
allantoin- safe conc.
safe and effective protectant at concentrations 0.5-2.0%
um...dry vs wet skin- choosing moisturizing products
If It’s Wet, Dry It= solutions, gels, some creams
If It’s Dry, Wet It= creams, lotions, ointments
normal skin- moisturizer choice (2)
Water-based, non-greasy feel
Cetyl alcohol, silicone derived ingredients
oily skin- moisturizer properties (4)
Water-based, oil-free, light in nature
Non-comedogenic
sensitive skin and mature skin- moiturizer properties to choose
Sensitive skin
Consider skin-type, avoid potential allergens

Mature skin (uhh like old people?)
Consider skin-type, likely need oil based
Treatment Approach to Dry Skin (4 steps)
Improve and maintain skin hydration
(humidifiers, keep room temp lower to prevent sweating DRINK)

Proper bathing- 1x a day, no hot water, short

Eliminate exposure to harsh agents and cold weather

Protect- emollient 3-6x daily, keratolytic, maaaybe mild corticosteroid
when to refer to PCP (4)
large areas, severe damage to skin integrity (splitting, cracking), or infection
appropriate use of moisturizers- when to apply/ how often...etc (3) which most effective
Apply at least two to three times daily
Apply immediately after bathing, showering
“Three-minute rule”?? wtf. apply within 3 min of finishing bath
Oil based products most effective
4 things to warn pt about moisturizers
Can be greasy and stain clothing
Avoid puncture wounds, infections or lacerations
Avoid eyes, mucous membranes, acne prone areas
Over application can lead to tissue maceration
hydrocortisone indications (3)
dry skin...maybe
Atopic or contact dermatitis
applying HTC (3)
Apply sparingly up to three to four times daily
Intermittent use recommended as response may decrease over time
cautions with HTC (3)
Avoid use in areas which may be infected
Caution on face
if face or large area involved- talk to PCP may need oral