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54 Cards in this Set

  • Front
  • Back
open angle glaucoma is common in what demographs
african american
mexicans
closed angle glaucoma is common in what demograph
Inuit
Chinese
Asian-Indian
what is normal IOP
<21 mmHg
what optic disk findings may you see in glaucoma
increase cup size
cup to disk ration > 0.5
cup to disk asymmetry > 0.2
what visual field changes may be seen in glaucoma
decrease peripheral vision
decrease contrast sensitivity
color alteration
what type of glaucoma is due to not enough aqueous humor exiting or too much being produced
open angle glaucoma
what type of glaucoma is due to mechanical blockage of trabecular meshwork
closed angle glaucoma
what type of glaucoma is a medical emergency
angle closure glaucoma
what agents cause drug induced glaucoma
anticholinergics
glucocorticoids
sympathomimetics
Jane is experiencing blurred hazy vision, sees halos around lights, and sometimes has head aches what type of glaucoma does she have
angle closure glaucoma

blurred vision, halos around lights, head aches are prodromal symptoms of Angle closure glaucoma
what is the IOP in closed angle glaucoma
40-90
what is the drug of choice to treat closed angle glaucoma
pilocarpine - use till you can perform iredectomy
when would pilocarpine be least effective
IOP > 60
what is the definitive form of treatment of closed angle glaucoma
iredectomy
other than pilocarpine what else can be used in the treatment of ___
used to treat closed angle glaucoma

can use hyperosmotic agents (mannitol, glycerin)
can you diagnose open angle glaucoma based on IOP
NO
ocular hypertension is seen in what type of glaucoma
open angle
what is ocular hypertension ("glaucoma suspects")
IOP > 22 mmHg
no change in optic disk or loss of vision
generally you don't treat optic hypertension unless patients have high risk factors, what are some of those risk factors
IOP > 25
optic disk:cup ration > 0.5
corneal thickness < 555micrometers
african american
family history
diabetes mellitus
what are the 1st line agents to treat ocular hypertension
beta antagonist
alpha agonist
prostaglandin analog
carbonic anhydrase inhibitor
what is the goal of treatment of POAG
decrease IOP by 30%
what is the IOP in normotensive glaucoma in POAG
IOP 10-12
what do you do when you increase the dose of a drug when treating POAG
increase the CONCENTRATION
not the # of drops
how long must you wait between administering another med when treating POAG
5-10 mins if using more then 1 med
Jen has blue eyes and wants to keep it that way, what drug would you prescribe for her POAG
beta blockers

good for pt with cosmetic issues
what agent would you use in a patient with a past history of CME or HSV and what agent would you not give her
beta blockers
brimonidine

don't give prostaglandin analogs in patients with past CME or HSV infections
beta blockers should be avoided in patients with
pulmonary disease (COPD/asthma)
diabetes
CV issues (CHF, 2nd/3rd degree heart block)
lactating
on oral Beta blockers
athlete
Jen has a hard time taking her medication what agent should you prescribe to treat her POAG
beta blocker
or
prostaglanding analog

good for compiance
Jain can't afford to be drowsy at any point in the day what agent should you give her
Prostaglandin analog - good when drowsiness is an issue

AVOID bromonidine
what agent should be avoided if pt has cosmetic concerns
prostaglandin analogs
Jain just had intraocular surgery what agent should she avoid
prostaglandin analogs
Jain is 8 months pregnant and has come down with POAG what agent can she not get
prostaglandin analogs

beta blockers (maybe if she's lactating)
Jain's 4 year old brother just came in the get treated for POAG what agent can you not give him
Brimonidine
what are SE of beta blockers
decrease HR
decrease BP
bronchospasm
mask hypoglycemia
change serum lipids
non specific beta blockers are preferred over specific in treatment of POAG what are the non specific BB and specific agents
non spicific
-timolol
-levobunolol
-metipranolol

specific
-betaxolol
If a patient is already on a BB for treatment of POAG what agent can you NOT add on
epinephrine or dipiverin
what are the prostaglandin analogs
Latanoprost (1st line)
Travoprost (1st line)
Bimatoprost (2nd line)

avoid in pregnancy
how do prostaglandin analogs work
reduce IOP by increasing trabecular outflow
what are the SE of prostaglandin analogs
change pigment color
foreign body sensation
conjuctival hyperemia (Red eye)
longer eyelashes
what is the order of SE in prostaglandin analogs
bimatoprost > travoprost > latanoprost

SAME EFFICACY IN DECREASING IOP
what are the alpha agonist for treatment of POAG
brimonidine
apraclonidine
Jain just came back from intraocular surgery and her IOP has increased what agent should you give her (she has POAG)
alpha agonist (indicated for post surgical IOP increase)

avoid prostaglandin agonist
what can alpha agonist be used in combo with
beta blockers
carbonic anhydrase inhibitors
latanoprost
what are the local SE of alpha agonist
lid edema
hyperemia
what are the carbonic anhydrase inhibitors
dorzolamide
brinzolamide
what are the local SE of carbonic anhydrase inhibitors
keratitis
Oral Carbonic anhydrase inhibitors are recommended for patients who failed topical what are their SE
increase uric acid production (avoid in gout pt)
altered taste
carbonic anhydrase inhibitors are contraindicated in patients with
electrolyte imbalance
sulfa allergy
respiratory acidosis
how do parasympathetic agents work
lower IOP by increasing aqueous humor outflow
Jane has brown eyes but Bill has blue who needs a higher dose of pilocarpine
Jane

Higher dose of pilocarpine needed in pt with darkly pigmented eyes
what agents can cause cataracts
cholinesterase inhibitors
cholinesterase inhibitors are contraindicated in patients with
asthma
narrow angles
hypotension
parkinsons
if a patient doesn't tolerate pilocarpine what can be given instead
carbachol
what agents decrease aqueous humor
beta blockers
alpha agonist
prostaglandin analogs
dopamine antagonist