Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
12 Cards in this Set
- Front
- Back
|
HYDANTOINS subgroups
|
Phenytoin
Mephenytoin Ethotoin |
|
|
BENZODIAXEPINES subgroups
|
Flurazepam
Triazolam Temazepam Lorazepam Diazepam Clonazepam |
|
|
PHENYTOIN (Dilantin)
|
-MAIN GROUP: Hydantoins
-MAO: decreases Na conductance during high frequency repetitive firing -USAGE: all seizures except Petit Mal |
|
|
MEPHENYTOIN
|
-MAIN GROUP: Hydantoins
More serious side effects than phenytoin |
|
|
ETHOTOIN
|
-MAIN GROUP: Hydantoins
Less effective than phenytpoin |
|
|
CARBAMAZEPINE (Tegretol)
|
MAO:decreases sodium conductance stablizing membrane
USAGE:All types of seizures except Petit Mal. Also used for bipolar disease and trigeminal neuralgia |
|
|
LAMOTRIGINE (Lamictal)
|
MAO:decreases sodium conductance stablizing membrane
USAGE:All types of seizures except Petit Mal. Also used for atypical absence. |
|
|
VALPROIC ACID (Depakote)
|
MOA: may inhibit the enzymes responsible for breakdown of GABA
(inhibitory neurotransmitter) USAGE: Primarily used for Absence Seizures and sometimes Grand Mal |
|
|
ETHOSUXIMIDE (Zarontin)
|
MOA: uncertain but may involve GABA but may reduce calcium currents in thalamic neurons
USAGE: absence seizure (DOC) |
|
|
PHENOBARBITAL (Luminal)
|
MOA: binds to allosteric site on GABA receptors causing chloride influx with resultant membrane hyperpolarization increasing channel opening duration
USAGE: drug of choice for Generalized Seizures and Status Epilepticus in infants and children and can be used for Focal Seizures |
|
|
PRIMIDONE (Mysoline)
|
MOA: drug metabolized to phenobarbitol; mechanism may be more like phenytoin
USAGE: generalized tonic-clonic seizures and partial seizures |
|
|
BENZODIAZEPINES
|
MOA: Binds to allosteric site on GABA receptor causing increased chloride ion influx with resultant neuron hyperpolarization prolonging channel opening duration
USAGE: diazepam (Valium), and lorazepam (Ativan) preferred drugs for Status Epilepticus and clonazepam used for Absence Seizures |
