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24 Cards in this Set

  • Front
  • Back

Plasma membrane

Flexible sturdy barrier that surrounds and contains the cytoplasm of a cell

Membrane lipids

Allows passage of many types of lipid soluble molecules, but act as a barber to the entry or exit of charged or polar substances

What are the functions of the plasma membrane?

1) acts as a barrier separating inside and outside of the cell


2) controls the flow of substances into and out of the cell


3) helps identify the cell to other cells


4) participates in intracellular signalling

Lipid bilayer

Two back to back layers made up of three types of lipid molecules - phospholipids, cholesterol and glycolipids

Phospholipid, cholesterol and glycolipid percentage

Phospholipid - 75%


Cholesterol - 20%


Glycolipids - 5%

Phospholipid

Lipid containing phosphorus


Hydrophillic head - polar


Hydrophobic tail - non polar

Cholesterol

Steroid with an attached OH group


Weakly amphipathic molecules


OH is the only polar region

Glycolipid

Lipids with attached carbohydrates group


Appear only in the membrane that faces ecf

Amphiphatic molecules

Have a polar and non polar parts

Integral proteins

Extend through/ into the lipid bilayer and are firmly embedded in it


Most are transmembrane proteins - span the entire length of the bilayer


Protrude into both cytosol and ECF

Peripheral proteins

Not as firmly embedded into the membrane


Attached to the polar heads of membrane lipids or to integral proteins

Glycoproteins
Proteins with CHO groups attached to the ends that protrude into the ECF

Glycocalyx

Acts like a molecular 'signature' - enables differentiation


Enables cells to adhere to one another in some tissues and protets cells from being digested by enzymes in ECF

Functions of integral proteins

Form ion channels


Act as carriers/ transporters


Called receptors - each receptor binds a specific type of molecule


Some are enzymes


Serve as linkers that anchor proteins in the plasma membrane of neighbouring cells



Glycoprotein function
Serve as cell identity markers
Funtions of peripheral proteins

Help support the plasma membrane


Anchor integral proteins


Participate in mechanical activities

What does membrane fluidity depend on?

Depends on the number of double bonds in the fatty acid tail


and


On the amount of cholesterol present

What effect does double bonds have on membrane fluidity?
Increases membrane fluidity by preventing lipid molecules from packing tightly

What does membrane fluidity enable?

Allows interactions to occur within the plasma membrane


Enables the movement of the membrane components responsible for cellular processes

Membrane permeability

Semipermable



The lipid membrane is highly permeable to...
Non polar molecules
Concentration gradient

Difference in concentration of a chemical from one place to another


E.g. inside to outside of the plasma membrane

Membrane potential

Difference in electrical charges between two regions


Also known as the electrical gradient

Electrochemical gradient
The combined influence of the concentration gradient and electrical gradient on the movement of a particular ion