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70 Cards in this Set

  • Front
  • Back

When should the ductus arteriosous close?

By 72 hours of life
the connection between the pulmonary artery and aorta should close
What causes the foramen ovale to close?
when the systemic blood presessure rises, and the pressure inside the left atria is greater than the pressure in the right atria.
Describe how a neonate thermoregulates by "non-shivering"
heat is produced by stimulating increased cellular respiration
Who has brown fat, where is it, and why is it important?
Brown fat is found in term infants, superfically deposited around the scapulae, neck, axillae, and around the kidneys. Has a higher capacity for heat production via metabolism
Neonatal Blood Volume?
80-85 cc/kg
How much water is the neonate?
75% water
What are the two high electrolytes in neonates?
Na and Cl
Why do babies have a greater risk for acid bluid up?
Have a higher metabolic rate that is twice as great in relation to their body size - also their renal system is immature and cannot concentrate urine well - setting the baby up for overhydration/dehydration/ and acidocis
How much can a neonatal stomach hold?
90 ml
When should the passage of meconium occur?
24-48 hours
T or F
Neonates have high stores of glycogen
faluse
Low stores of glycogen, making them more prone to hypoglycemia
Why do you see physiologic jaundice?
the liver is immature, and there are lower levels of glucronyl transference which is required for bilirubin conjugation
When do digestive enzymes mature
3-6 mths
When should a neonate void
24 hours
What causes milia
blocked sebaceous glands
What is vernix caseosa?
in utero coat produced by the sebacsous glands of the baby, that protect it against the acidic amniotic fluid
T or F

A baby has more cartilage at birth
True, grows into bones by oslification
What purpose does hypertrophy cause
encourages muscle growth and development
When can a baby produce their own immunioglobulins?
at 2 mths of age
T or F
The autonomatic nervous system is critical to the sucessful transition towards extrauterine life
Ture
What direction does myelination proceed?
cephalocaudaul-proximodistal - this is why children mater gross moter skils b4 fine motor skils
If a baby is discharged from the hospital less than 48 hours of birth when do they need to see a PCP
With in 48 hours
What are the three normal newborn issues
bonding
breast/bottle feeding
bilirubin
What is the acceptiable weight loss for babies
10% of their body weight by the first five days and then regain it during the next five days
How much weight does a baby gain
2/3 oz a day
20-30 gms a day
How long with the baby grow in the first month?
Length will incrse between 1-1.5 inches (2.5 - 4 cm) in the first month
What is the head circumference in the first moth
1 inch (2.54 cm) in the first month
What is the formula intake for babies
2-3 oz per lb of weight per day
about 4-6 oz a feed
How often should bf occur?
2-3 hours for 10-15 min per brest
Average wet diapers per day
6 diapers per day
A baby is brought to you with spit ups, no weigh gain, irritability - what should you think?
GERD refleux
why do spit ups occur
cuz the musclar valve between the stomach and esophagus is immature
How do motor movements change over the first weeks
The babies movements are jerky and become much smoother by the end of the first months
How far can a baby see
8 - 15 inches in front - in 1 month can view 3 feet
When should hearing aids be introduced
b4 3 months, no later than 6 mths
Are hearing screen test 100% fool proof in identifying children with hearing problems
No - only about 50% of significant congenital hearing loss
at a minimum can spot hearing loss with sigificant bilateral hearing
What is the ABR - aiditory brain response?
an electral waveform generated by neuronal activity in the auditory nerve and breainstem pathway following clicking sounds
T or F

The ABR can differentiate between conductive and sensorineural hearing loss
True
Biliribin is only from degradation of hemoglobin

T or F
False
20-30% is from nonerythroid tissue
In utero what eliminates the bilirubin
Placenta -

but also stool and amniotic fluid
What is the underling cause of kernicterus
Unbound bili to the albuim sites - the bilirubin circulates freely in the plasma and migrates into the brain cells
When does bilirublins metabloism peak
Term baby day 2- 4
preterm baby 5-7
Why are y, and z proteins (ligands) important?
They combine with the biliruin once it is transferred across the cell membrane - and is stored or removed from the proteins and conjugated in the hepatic ER
what is glucuronic acid?
A chemical that bilirubin attaches to inorder to become bilirubin glucuronide
What is bilirubin glucronide
the form of bilirubin that can be excreeted into the bile and into the intensine
What is urobilirubin
the inconjugated form of bilirubin that in formed after intestinal flora reduces it
What does bilirubin glucuronidase do
breaks down conjugated bilirubin and then the intestines reabsord it
When does jaundice occur
when the production of bilirubin exceeds the newborns liver's ability to conjugate and elimate it
What is the treatment of hyperbilirubeinmia dependent upon
Gestational age
Birth weight
Clinical Course
Rate of rise of level (.5mg/dl/h)
Rate of hemolysis
What are the two ways to treat hyperbilirubinemia
Phototherapy
Exchange transfusion
How quickly does the phototherpy work
1-2 mg/dl
What is an abnormal rise in bilirubin
.5mg/gl/h
What is the amount of bilirubin that is removed from double volume exchange transfusion
25%
what is photo-oxidation
oxidation of bilirubin pigment deposited in the skin and its conversion into colorless produces excreted in the urine
What is photoisomerization
conversion of bilirubin plymers in skin to excretable isomers that converts from lipid souluble substance to two water-solubel isomers
What happens to the two water soluble isomers
one isomer stays conjungeted and is excreted in the bile, one isomer (liibilirubin) is elimanates throuigh urine and bile
What is the goal of exchange transfusion?
Remove biliribin, antibody coated RBC's, circulation maternal antibodies, Rh positive fetal cells and hemolyzed cells from the newborn circulation
What happens with rebound levels within one hous of exhange transfusion?
are as high as 55% of preexchange level
Whats the blood volume in the exchange transfusion?
80cc/kg
A pt has polycethemia, what type of exchange transfusion is needed
Partical exchange transfusion
What type of blood is needed for exchange transfusions?
whole cross - matched blood
What lab values need to be monitored for exchange transfusion
CBC, electolytes, Ca, glucose, bilirubin levels before, during, and after the procedure
Mother is Hep. B positive, how do you treat the baby
the baby should recieve both the vaccination and IVIG
The mother is hep. B is unkown, what is the treatment?
you have 12 hours to obtain and give the vaccination and IVG for pretems - term babies can be given with int the first week of life
The mothers hep b status is negative, what is the tx?
the vaccine should be given with parental consent
What is the criteria for early discharge?
Vag delivery, AGA single birth, 38-42 weeks, VSS for 12 hours, baby has urinated and passes stool, 2 successful feeding with documentation
What lab values must be looked at b4 early discharge
maternal syphillis
hep B antigen
Infant blood type
direct coombs
If a family does not want hep B what must occur?
PCP visit within one week
How long must a baby be supine to sleep
fisrt 6 mths
A baby is discharged 12 hours post delivery, when should a PCP appointment be made
at 48 hours of life