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178 Cards in this Set

  • Front
  • Back
what does circulatory refer to?
a system in motion
what does cardiovascular refer to?
the structural components of the system
primary functions of the cardiovascular system
to EXCHANGE gas and TRANSPORT energy, nutrients, and waste products
the mammalian heart has how many chambers? what are these chambers called?
it has 4 chambers. there are 2 ATRIA and 2 VENTRICLES. (L/R). atria are the collecting chambers with thin walls, ventricles have thick walls that are more powerful to pump blood out of the heart
the heart cycle has a sequence of events with each heart beat called systole and diastole. what do these mean?
systole- heart contracts, ventricles pump blood into vessels

diastole- ventricles fill with blood
what does the systolic and diastolic events diagnose?
hypertension- too high of blood pressure

hypotension- too low of blood pressure.

120/80 -first number is systolic, second number is diastolic. measured in mmHg.
what is blood pressure?
the measure of the amount of force you blood is exerting on the walls of the vessels.
what do heart valves prevent?
the backward flow of blood in the heart
there are 2 ATRIOVENTRICULAR valves between the atrium and the ventricle.
tricuspid valve- separates R atrium from R ventricle

mitral valve- separates L atrium from L ventricle.
there are 2 SEMILUNAR valves
pulmonary semilunar- at exit of right ventricle

aortic semilunar- at exit of left ventricle
what is a pulse?
the smaller vessel has to expand which is the pulse. (artery needing an arteriole)
pathway blood travels through the body
heart to arteries to arterioles to capillaries (gas exhange) to venules to veins back to the heart.
arteries and veins are distinguished only by the direction in which they carry blood- NOT by the quality of the blood itself.
ARTERIES---- AWAY
VEINS---TO
cardiac output
the volume of blood pumped by the heart PER MINUTE
blood vessel response to cardiac output
vasodialation- blood vessels expand from increased cardiac output.

vasoconstriction- blood vessels constrict from reduced cardiac output
STROKE VOLUME
the volume of blood in ML pumped out of the heart with EACH BEAT
cardiac output equation (in ML/MIN)
heart rate (beats/min) x stroke volume (ml/beat)
double circulation
humans have double circulation to separate oxygen rich blood from oxygen poor blood.
pulmonary circuit
oxygen poor blood taken to the lungs to pick up oxygenated blood.
systemic circuit
oxygen rich blood pumped by the heart to the rest of the body
blood is what type of tissue?
blood is connective tissue
blood is..
cells distributed in a liquid matrix called plasma
whole blood
blood cell + plasma
how much blood is circulating through the body?
humans have 4-6L circulating in body
plasma
55% of blood volume

most (90%+) of plasma is water

the other 10% are solutes dissolved in the water, making it viscous (thick)
solutes in plasma
lipids, salts, vitamins, hormones, waste, plasma proteins
plasma proteins have..
immunoglobulins (antibodies)- specific proteins produced in response to a foreign substance in the body.

clotting factors- help blood clot

serum- plasma without clotting factors
what activates clotting factors?
thrombin, an enzyme is needed to activate clotting factors.
serum can be used for what?
diagnostic material and eye drops
blood cells
red blood cells (rbc's)

white blood cells (wbc's)

platelets
rbc's
are also called erythrocytes

they are produced from erythroblasts

THESE ARE NOT PRODUCED FROM MITOSIS MUST BE PRODUCED BY AN ERYTHROBLAST
function of red blood cells
to carry oxyen which is attached to HEMOGLOBIN (protein) as they pass through lungs.

stacks of red blood cells, called ROULEAUX flow through blood vessels as capillaries and exchange gasses.
red blood cell is permeable to
water, oxygen, and carbon dioxide. they move by DIFFUSION
red blood cells lack...
mitochondria and nucleus but CAN undergo glycolysis which produces a very small amount of ATP.
white blood cells
also called leukocytes. less numerous than red blood cells.

they HAVE nuclei and mitochondria.
5 types of white blood cells
lymphocytes, neutrophils, monocytes, eosinophils, and basophils
purpose of white blood cells
fight infection
leukocytes mature in...
lymphoid organs... (spleen, thymus, tonsils, adenoids, lymph nodes). we can lose some of these organs but we can not lose them all!
platelets
produced in bone marrow from a cell called a MEGAKARYOCYTE
function of platelets
-blood clotting

-store and transport chemicals (serotonin, epinephrine, histamine)
end of cardiovascular
end of cardiovascular
human digestion purpose
supply cells with energy in a useful form (ATP)
steps to digestion
salivation, ingestion, mechanical breakdown, chemical breakdown, metabolize compounds, excrete waste
what is a hormone?
a chemical substance produced in the body that controls and regulates the activity of certain cells or organs. THE CONTROL.. TELLS ENZYMES WHAT TO DO
what is an enzyme?
a substance that initiates a chemical reaction
what is a true organ?
what touches the food or substance directly. (tongue, esophagus, stomach, duodenum, small intestine, large intestine, rectum, anus)
complete digestion
where the food goes in, does not come back up.
oral cavity
physical and mechanical digestion

smells, taste of food trigger salivary glands to produce saliva
saliva contains...
mucin- lubricates and protects mouth

buffers- offsets acids in stomach (pH)

bolus- forms ball (food to swollow)

salivary amylase ENZYME- breaks down starch
ingested food forms...
a bolus- forms ball (food to swollow)
pharynx
this is a region not a structure
what systems join in the pharynx?
digestive and respiratory
structures in the pharynx
epiglottis, glottis, trachea, esophagus
esophagus is..
a long tube extending between pharynx and stomach
the top portion of the esophagus consists of.. while the remainder is..
top portion is voluntary skeletal muscle and the remainder is involuntary smooth muscle
mammalian digestive tract has a 4 layered wall
mucosa- mucosal epithelial layer (innermost)

submucosa -connective tissue (blood vessels and nerves)

muscalaris- smooth muscle

serosa- connective and epithelial tissue (outermost layer)
what is perforation?
puncturing all four layers which allows bacteria to attack body.
what is peristalsis?
an action or activity. rhythmic waves of contraction of the smooth muscle sphincters moving digested food in one direction.
what is a sphincter?
thickened muscular regions that cause peristalsis
accessory glands and organs of digestion
salivary glands- 3 pair

pancreas

liver

gallbladder
stomach
functions to store, mix, transport, and chemically breakdown substances
how much food can the stomach hold?
2L
what are the two regions of the stomach?
fundus and antrum.

fundus is the upper part closest to the esophagus

antrum is lower part closest to the small intestine
HORMONE GASTRIN
produces gastric juices (hcl and pepsin)
pepsin is...
an enzyme that begins the breakdown of proteins
food + gastric juice =
acid chyme
what are the valves/doorways of the stomach?
cardiac orifice- regulates food from esophagus into stomach

pyloric sphincter- regulates passage of food from stomach into small intestine
how long is the small intestine?
about 6m long
first 25cm of human small intestine?
the duodenum
what is the function of the small intestine?
breakdown of all classes of macromolecules and nutrient absorbtion
what three organs contribute to digestion?
pancreas, liver, and gallbladder
what is the function of the pancreas?
produce ENZYMES and alkaline bicarbonate to offset acidity of acid chyme from stomach. turns acid chyme into just chyme
what is the digestive role of the liver?
bile production which is needed to emulsify lipids. lipids are hydrophobic intestines are hydrophilic. bile helps digest the lipids.
what is the function of the gallbladder?
bile storage
how do substances digest in the small intestine?
acid chyme plus the products of the accessory organs chemically break down nutrients. allows the small intestine to absorb nutrients
4 HORMONES OF DIGESTION
GASTRIN

SECRETIN- releases bicarbonate from pancreas

CCK- releases bile from liver/gallbladder

ENTEROGASTRONE- inhibits peristalsis to allow the absorbtion of nutrients
large intestine is connected to the small intestine by what?
the t shaped junction (ileocecal junction)
one short arm of the t is called the..
cecum. the appendix protrudes from this location
function of the colon
reabsorbtion of water- 7L daily

as water is reabsorbed the remaining organic matter or feces is compacted. (becomes more solid)

takes 12-24 hrs for materials to travel length of colon
rectum
terminal portion of colon, more layers of muscle
anus
opening of the rectum
e.Coli
intestinal bacteria which live symbiotically on orgain matter of colon

bacteria produce vitamin k as a bi-product of their metabolism
diarrhea vs constipation
too litter water absorbtion- diarrhea

too much water absorbtion- constipation
end of digestion
end of digestion
asexual reproduction
a form of reproduction that does not require the union of egg and sperm to form a zygote (no meiosis)

offspring are genetically identical to the parent

minimizes genetic diversity

oldest means of reproduction on the planet
examples of asexual reproduction
budding- new individual buds from parent.

fragmentation- dividing one into two

regeneration- regrowth of a body part
parthenogensis
female egg develops without being fertilized by sperm. have no sex chromosomes. 100% female
sexual reproduction
requires the fusion of a male and female gamete (meiosis) to form a diploid zygote

increases genetic diversity
heterogamy
some organisms have the ability to switch between parthenogensis (asexual) and sexual reproduction depending on environmental conditions
simultaneous hermaphroditism
individuals have functional male and female reproductive organs. common in sessile and burrowing organisms. NOT AN ACCIDENT.
sequential hermaphroditism
organisms switch sexes during lifecycle

protogynous- born female switch to male

protandrous- born male switch to female

may or may not switch
external fertilization
eggs are shed out of female then fertilized by male gamete

many eggs produced
few embryos survive
requires a MOIST enviornment
internal fertilization
sperm deposited in female reproductive tract

one/few eggs fertilized
high survival rate
cooperative behavior
oviparity
females lay eggs which develop outside the mother
ovoviviparity
females give birth to live young which are hatched inside mother

good for if you are always on the move like sharks or snakes
viviparity
females give birth to live young which required nourishment from mom, through a placenta umbilical chord

no hard shell eggs, (humans)
external genitalia
scrotum (temp regulation)

penis (organ of copulation)
internal organs
testes, epididymis, vas deferens, urethra
testes
sperm production within seminiferous tubules
epididymis
sperm maturation
vas deferns
duct through which sperm travels out of epididymis
urethra
tube connecting and draining urinary and reproductive systems
male reproductive glands
glands contribute to secretions to sperm forming semen.

seminal vesicles, prostate gland, bulbourethal gland
seminal vesicles
make sperm motile, repress female immunity (60%)
prostate gland
nourish sperm (25%)
bulbourethal glands
neutralizes pH of urethra (15%). makes a safe passageway for sperm
female reproductive organs
ovaries, ovulation, corpus luteum
ovaries
egg production and storage, female gonads
follicles
eggs contained within ovaries are nourished and protected by follicles.
ovulation
egg expelled from follicle
remaining follicle grows within ovary as a mass of tissue called what?
corpus luteum
corpus luteum
secretes HORMONE PROGESTERONE; this later disintegrates if the egg is not fertilized.
primary oocytes (~40000) are present when?
prior to birth. secondary oocytes are released during ovulation
oviduct
ducts leading out of ovaries, egg travles through duct
uterus
site where egg implants for development. lining is ENDOMETRIUM
cervix
opening of uterus
vagina
birth canal; copulatory organ
what is shed during the menstrual cycle?
endometrium
sex hormones
a chemical substance produced in the body that controls activities of cells or organs
MALE HORMONE- TESTOSTERONE
important for development of primary and secondary sexual characteristics. primary is actual organs, secondary is responsible for puberty
MALE HORMONE- GnRH
secreted in hypothalamus, regulates production of...
MALE HORMONE- LH
secreted by pituitary gland, stimulates production of testosterone
MALE HORMONE- FSH
secreted by pituitary gland, stimulates sperm production in testes.
LOOK AT DIAGRAM MADE IN CLASS
ON BACK OF PAGE 13
female hormones
hormones coordinated the menstrual and ovarian cycle
FEMALE HORMONE-GnRH
screted in hypothalamus; stimulates production of...
FEMALE HORMONE- FSH
stimulates follicle development
FEMALE HORMONE- LH
triggers ovulation
estrogen and progesterone
secreted by corpus luteum

inhibits GnRH (which then limits FSH, LH)

maintains endometrium

development of primary and secondary sexual characteristics
HCG
not produced by female, only embryo.

embryonic hormone- maintains secretion of estrogen, progesterone by corpus luteum through first trimester of pregnancy
LOOK AT SPERM STRUCTURE ON PAGE 15
memorize acrosome, head, midpiece, tail
head of sperm
contains nucleus and acrosome
middle piece
contains mitochondria
tail
beating flagellum
acrosome of sperm contains..
digestive enzymes

needed to penetrate 2 barriers surrounding egg (corona radiata, zona pellucida)
only one sperm can fertilize an egg
egg cell uses two strategies

fast block to polyspermy- depolarization of egg membrane

slow block to polyspermy- inactivation of receptors on egg membrane
science defines conception as...
the nucleus of the sperm hits the cytoplasm of the egg
after egg has been fertilized...
the events that occur are
-cleavage
-gastrulation
-organogensis
cleavage (to split)
withiin a few hours of fertilization

zygote rapidly divides

no embryonic growth

morula to blastula (blastocell)
gastrulation
blastula to gastrula, notochord develops.

notochord all vertebrates have hollow nerve chord running down spinal chord.
3 layers in gastrula
ectoderm, mesoderm, and endoderm
organogensis
organ development
positive pressure breathing
(frogs) - does not utilize chest wall/ diaphragm, instead this requires the gulping and swallowing of air
negative pressure breathing
(reptiles, birds mammals) - utilize diaphragm and chest muscles to breathe
inhilitaion
diaphragm contracts, increases the volume of thoracic cavity
exhalation
diaphragm relaxes, decreases volume of thoracic cavity
residual volume
small amount of air in the lungs after breathing out
respiration
exchange of gasses, oxygen and carbon dioxide
breathing
the alternate inhalation and exhalation of air
respiratory cycle
inhalation + exhalation (one cycle is one breath in and one breath out)
tidal volume
in humans is about 500mL (amount of air exchanged in the respiratory cycle)
vital capacity
the maximum amount of air that can be exhaled after a maximum inhilation
pathway of air
nasal/ oral cavity, pharynx, bronchi (left and right), bronchioles (branches network of air passages leading into the lungs), alveoli.
alveoli
the site of gas exchange

pulmonary capillaries surround alveoli

most oxygen entering the blood combines with hemoglobin to form oxyhemoglobin
who was the father of evolution?
charles darwin

published on the origin of species by means of natural selections

was a naturalist on the HSM beagle from 1831-1836
prior to darwin
creationism was the accepted idea on how life originated

species were static, or extinction was not considered

earth was though to be around 6000 years old
what is evolution?
process by which the characteristics of a population change over time through inheritance
population
a group of individuals of the same species living in the same defined area
evolution is a scientific..
THEORY not a fact. but has substantial evidence.

not a term used by darwin
scientific theory
a hypothesis that has been rigorously tested through the scientific method with little modification and has abundant data to support the hypothesis
scientist who influenced darwin
cuvier- made fossil discoveries, identified extinct species, showed the species were able to become extinct which intrigued darwin.

lamarck- acquired charateristics hypothesis. (soft inheritance) animals gained traits because of the enviornment and could pass them onto their offspring.

lyell- principles of geology, proved that earth was a couple mill years old through the study of rocks.
Alfred Russel Wallace
influenced darwin and was the closest to his findings, he formulated a similar theory but allowed darwin to state his findings because he has much more evidence and proof.
4 mechanisms of evolution
mutation
genetic drift
migration
natural selection
mutation
2 types
-point mutations
-chromosomal alterations

results from an error in the DNA copying process
-can be spontaneous or ENVIRONMENTALLY driven
genetic drift
random change in allele frequencies in a population.

more important evolutionary factor in small populations
special cases of genetic drift
founder effect- a new population breaks off from the source population and creates a bigger diversity for that species

bottleneck- often due to famine, disease, or rapid environmental change
migration
also known as gene flow

influence by the mobility of the species

influenced by geographic behaviors

example- wind carries seeds far beyond the bounds of the parent plant population.
essential conditions for natural selection
variations for a trait

the trait must be heritable

differential reproductive success
natural selection IS
a selective process of change through time in a population

a change in the alleles of a population

environmentally dependent

a driving force of evolution
natural selection is NOT
directed by a guiding hand

survival of the fittest. fittest means how many offspring left behind. not the strength of an animal

production of perfection

humans evolving from monkeys (we all evolved from something prior)
5 rules of natural selection
populations tend to increase indefinitely in a geometric ratio

populations numbers must stabilize at a certain level- lack of resources prevent the population from increasing to infinity

there is a struggle for existence- not all organisms can survive

there is variation within each species

as organisms struggle to survive those individuals that are better adapted to the environment leave behind more offspring than those that are less adapted- organisms are "more fit"
artificial selection
the process of intentional or unintentional modification of a species through HUMAN ACTIONS which encourage the breeding of certain inherited traits over others (corn crop)
sexual selection
acts on an organisms ability to obtain (often by any means necessary!) and successfully copulate with a mate.

true natural selection
evidence for evolution
fossil record
comparative anatomy
biogeography
dna comparisons
convergence of evidence
no one piece of evidence alone is enough to form a theory. instead there has to be an aggregate supply of evidence in order to turn a hypothesis into a theory.
fossil record
gradual transition in the fossil record from simple organisms to complex organisms

older rock strata has less complex fossils newer rock strata have more complex fossils but retain some of the characteristics of the earlier fossils

shows link between species for the theory of evolution. linking fossils from old - new allows us to realized that each species has led to another.
comparative embryology
useful for vertebrate animals as evidence for evolution

embryonic stage of vertebrates is similar in early development.

mid stage development is more alike for more related species

limit- only to support evolution for vertebrates

late stage development shows definite difference

individual patterns of development repeat the ancestral pattern of development
biogeography
distribution of life on earth

species are distributed around the globe largely in relation to their relationships to one annother

if life form arose independently it would make more sense for them to exist wherever an environment could support them as opposed to being distributed according to their apparent relationship to other life forms