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82 Cards in this Set

  • Front
  • Back

What type of circulatory system do mammals have?

A closed, double circulatory system.

What does a closed system mean?

Blood is confined to vessels (arteries, arterioles, veins and capillaries)

What does a double system mean?

Blood passes twice through the heart for each complete circuit of the body.

What does blood do?

It transports respiratory gases, products of digestion, metabolic waste products and hormones around the body.

What does the pulmonary artery do?

Carries blood from the heart to the lungs

What does the pulmonary vein do?

Carries blood from the lungs to the heart

What does the aorta do?

Carries blood from the heart to the body

What does the vena cava do?

Carries blood from the body to the heart

What does the renal artery do?

Carries blood from the body to the kidneys

What does the renal vein do?

Carries blood from the kidneys to the vena cava.

What does the right side of the heart do?

It pumps deoxygenated blood to the lungs

What is the pathway of blood through the right side of the heart?

Vena cava--> right atrium-->right atrioventricular valve-->right ventricle-->semi-lunar valve-->pulmonary artery-->lungs

What does the left side of the heart do?

It pumps oxygenated blood around the body.

What is the pathway of blood through the left side of the heart?

Lungs-->pulmonary vein-->left atrium-->left atrioventricular valve-->left ventricle-->semi-lunar valve-->aorta-->body

How many chambers does the heart have and what are they?

4


2 atria


2 ventricles

What is a difference between the atria and the ventricles?

Ventricles have thicker walls than the atria so they can push blood out of the heart.

Why do atria have thinner walls?

They only need to push blood from the atria into the ventricles, the distance is smaller.

Which ventricle has a thicker wall and why?

The left ventricle as it has to pump blood all around the body, whereas the right only has to pump blood to the lungs

What does the septum do?

It separates the 2 sides of the heart, so oxygenated and de-oxygenated blood don't mix.

It also enables there to be different pressures on each side of the heart.

What is the difference between the superior and inferior vena cava?

The superior is at the top of the heart, the inferior is at the bottom

What are the 2 types of valves in the heart?

Atrioventricular valves


Semi-lunar valves

What can be seen on a diagram of the outside of the heart?

The left and right coronary arteries

What do the left and right coronary arteries do?

They supply the heart with blood and oxygen because it doesn't use the oxygen that passes through the left side of the heart.

What do arteries do?

They carry blood from the heart to the body.

What do they form?

They divide into smaller blood vessels called arterioles to form a network throughout the body.

What is the lumen like in the artery?

It's small to maintain the blood pressure

What is the wall of the arteries made of?

Endothelium, collagen fibres, fibrous proteins, elastic fibres, smooth muscle

What is the function of the collagen fibres and fibrous proteins?

They mean that the thick wall can withstand high pressure.

What is the function of the elastic tissue?

It allows the wall to stretch and recoil to maintain diastolic blood pressure

What are two features of the endothelium and what do they do?

It's smooth to reduce friction and folded so it can unfold when the artery stretches.

What does the smooth muscle do?

It allows contraction and vasoconstriction which narrows the lumen

What does the smooth muscle do in arterioles?

It enables blood to be directed to different areas of demand in the body. Muscle contracts to restrict blood flow and relaxes to allow full blood flow.

What is the pressure like in arteries?

Blood is at very high pressures due to the contraction of the left ventricle muscle.

What do veins do?

They carry blood back to the heart

What is the lumen of the veins like?

It's large to ease the flow of blood

What are the walls of veins made of?

Endothelium, collagen, elastic fibres, smooth muscle but there is less of this than there is in arteries.

What is the wall like?

Thin but strong

What else do veins contain?

Valves which prevent the back flow of blood

How is blood moved through the veins?

Heart pressure is exerted by the movement of the muscles and there's some residual pressure from the contraction of the left ventricle muscle wall

What is the pressure like in the veins?

The blood is at a low pressure

What do arterioles branch into?

Capillaries

What is the role of the capillaries?

Molecules are exchanged between the capillaries and cells.

What forms the wall of the capillaries and effect does this have?

A single layer of endothelial cells. They're only 1 cell thick which reduces diffusion distance

What is the lumen like in the capillaries and what does this mean?

It's narrow and the same diameter as red blood cells. This means erythrocytes are squeezed through and reduces diffusion distance.

What is a feature of the endothelium?

It's smooth to reduce friction for blood flow

What is another feature of the endothelium?

There are gaps between endothelial cells to allow nutrients to pass through.

What can't pass through these gaps?

Proteins

What is a feature of capillaries?

They have a large surface area which increases rate of diffusion.

What is pressure like in the capillaries?

It's high at the arteriole end due to the contraction of the left ventricle wall but pressure falls as it goes towards the venous end.

Which blood vessel has the thickest walls in descending order?

Arteries


Veins


Capillaries

Which blood vessel has the highest blood pressure in descending order?

Arteries


Capillaries


Veins

Why does pressure decrease in the different blood vessels?

As you go further from the heart, the vessels branch and the cross sectional area increases.

Why does pressure in the veins fluctuate?

This is due to the left ventricle muscle wall contracting and relaxing. Contractions raise pressure.

What else can be found in the heart?

Tendinous chords

Why does systole mean?

Contraction of cardiac muscle

What does diastole?

Relaxation of cardiac muscle

How long does the average cardiac cycle last?

0.8 seconds

What is the average heart rate?

75 beats per minute

How many stages of the cardiac cycle are there?

3

What happens in stage 1?

The atria fill with blood and contract (atrial systole). This decreases the volume and increases pressure. This opens the atrioventricular valve allowing blood to enter the ventricle.

What happens in stage 2?

The ventricles contract (ventricle systole) which decreases volume and increases pressure. Atrioventricular valves shut and semi-lunar valves open.

What happens in stage 3?

The ventricles and atria relax (diastole) and the semi-lunar valve closes. Atria fill with blood and the cycle starts again.

When do valves open?

When the pressure below the valve is greater than the pressure below it.

When do the atrioventricular valves open?

When the pressure in the atria is greater than the pressure in the ventricles.

When do the semi-lunar valves open?

When the pressure in the ventricles is greater than in the arteries.

When do valves close?

When the pressure above them is greater than the pressure below.

Why do valves close?

To prevent the backflow of blood.

What do tendinous chords do?

They prevent the valve inverting

What happens to aortic pressure in the 3 stages?

Atrial systole- constant


Ventricular systole-increases


Diastole-decreases

What happens to ventricle pressure in the 3 stages?

Atrial systole- increases

Ventricular systole-rapidly increases


Diastole- rapidly decreases

What happens to atrial pressure in the 3 stages?

Atrial systole- increases

Ventricular systole-decrease, then increases


Diastole- decreases then increases

What happens to ventricle volume in the 3 stages?

Atrial systole- increases slightly

Ventricular systole- decreases


Diastole-increases

What does an ECG show ?

In atrial systole, the trace decreases, it then begins to rise and peaks in ventricular systole (highest peak). It decreases again and slowly rises. It remains steady during diastole.

What does an ECG do?

It monitors the electrical activity of the heart and turns it into a trace.

What generates electrical activity?

The heart. It spreads through nearby tissue and sensors on the skin pick up the electrical excitation created by the heart.

What is the equation for cardiac output?

Cardiac output=heart rate x stroke volume

What is cardiac output measured in?

cm3 min-1

What's stroke volume measured in?

cm3

What's heart rate measured in?

min-1

What is cardiac output?

The volume of blood pumped by the heart per minute

What is stroke volume?

The volume of blood pumped during each heart beat

What is heart rate?

The number of beats per minute