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32 Cards in this Set

  • Front
  • Back

Cornea

transparent cover of the front of the eye




uneven cover causes astigmatism




sclera is the white cover over the eye ball

Iris

muslce that contracts or relaxes to control the amount of light entering the eye

Ciliary body

muscle that controls lens shape

Choroid

vascular layer of the eye

Retina

sensory tissue

Optic nerve

contains the ganglion cell axons that run to the brain




contains blood vessels that open into the retina to vascularize the retinal layers

The lens

transparent body located behind the iris




a lens that loses its transparnecy is called a cataract




cataracts are common in the aged populaiton




inverts the image




needed to focus the image, suspened by ligaments connected to teh ciliary body




amount of contraction of teh ciliary body muscles determines the shape of the lens

Presbyopia

loss of flexibility within the lens




produces difficulty focusing on close objects




occurs around age of 45

Aqueous humor

located in the anterior (between cornea and lens)and posterior chamber (between the iris and the lens)

Vitreous humor

between the lens and the retina




gelatinous and fills the back of teh eye

Retina

neurons, glia, pigmented epithelium and blood vessels




light passes through the lens through the inner layer of ganglion cells and bipolar cells to reach the rods and the cones

Photoreceptors

located distally to the front of the retina so it has to move through the layers of the retain before being recognized

Optic disc

papilla




origin of nerve




blind spot

Macula

contains the fovea




yellow pigmentation of the macular area is known as the macula lutea




cones in teh area die which can cause blindness`

Retina layers

photosensors




interneurons




ganglion cells which are innermost

Phototransduction in the dark

Na and Ca enter the rod cell and causes transmitter release




this decreases with light




cGMP remains high during the dark which keeps the CNG cation channels open, relies on rhodopsin not being acticvaed

Activated rhodopsin

triggered by light




activated transducin




activated PDE




decrease cGMP




decrease positive charge entering




decrease AP

Cone opsins

similar to rhodopsin




but only absorb light of certain wavelength

Cones vs rods

125 million rods, specialized to function under dim conditions




6.4 mil cones, function in well lit rooms and mediate color

Fovea

lies in the center of the macula




central region contains only cones




overlying retinal layers are displaced




rods are displaced to the peripherary with poor resolution of small objects

Retinitis pigmentosa

hereditary disease of the retina for which there is no cure at present




caused by at least 10 different mutations in the phototransduction cascade




leads to loss of peripheral bision and can progress to total blindness




gene therapy to replace fault rhodopsin gene is in trials

Retinal interneuosons

many photoreceptors synapse onto one interneuron and a single interneuron will synapse on many ganglia and other interneurons

Ganglion cells

about a million cells




at least 18 different morph types of the ganglion cell in the human retina




changing features in areas of the eye




differences convery changes in spatial and temporal contrasts

Visual vs receptive field

visual is the whole area seen by the eye




receptive field refers to the part of the visual field that affects a particular visual system neurons

Center surround receptive fields

ON center fires action potential but OFF center inhibits




fires fastest if there is a small spot of light centered in the receptive field, responds less to a larger sport of light

Off center On surround

fires when the surround is activated




respond best to a small dark spot on a bright background




neither type responds welll to an all bright or all dark field

Sustained vs transient responses

sustained will fire during the entire length of the activationg where as transient will fire only a couple times then stop

Other ganglion ttypes

some project to superior colliculus and are involved in eye movement




some to suprachiasmatic nucleus that control circadian rhythms

Receptive field size

ganglion cell centers in the fovea and are as small as a fraction of a degree




where as the peripheray can be 100 times bigger




in the fovea, smaller fields would result in less convergence due to only light in the center of teh receptive field causing activation, high spatial acuity




peripherary has photoreceptors with large amounts of convergence, which will allow for the greatest amount of light to be acquired but low sensitivity to spatial resolution

Color vision

Red green center surround is very common




blue-yellow used as well




if you activated a center green on and red off a large red stimulus will turn off and then fire when removed

Color vission

occurs because located close on X chromosome




recombination errors can result in defects

Fovea vs peripheray

sustained, color selective, small field, some on some off center




transient, broad band, larger field, mix of on and off center