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8 Cards in this Set

  • Front
  • Back

Which viruses CAN cause sporadic, acute gastroenteritis in adults?



Calcivirus


Adenovirus


Rotavirus


Astrovirus

ALL of them can cause sporadic gastroenteritis in adults.



Calcivirus (norovirus) is most common

7 mo old female


2 day history of watery diarrhea with fever 12 hours earlier


No history of vomiting


Hyperleukocytosis with neutrophilia and increased C-reactive protein in blood


Negative bacterial culture 3 days later



What is the possible virus or bacteria?

Rotavirus

If not rotavirus, what else could be on the differential?

Astrovirus


Enterovirus D68 (actually a respiratory virus)


Adenovirus 40


E. coli (but stool cultures were negative and there is usually a more bloody diarrhea, not watery).

What is an orphan virus?

Virus not associated with a particular disease.

If the rate of rotavirus infection is similar for all infants regardless of geographical location or socio-economic status, why is there such a disparity in rotaviru mortality between developing and developed countries?

Availability of emergency health care and roper management of the disease through effective fluid and electrolyte replacement.

Influenza virus and rotavirus both have segmented RNA genomes. Which of the following statements about the replication of these viruses is true?

Both viruses have capped mRNAs, but only influenza mRNAs undergo splicing.

Know the 1982 disease guidelines for norovirus

Medscape?

Entero-toxins are heat stable proteins released form microbes that target the intestine and alter apical membrane permeability resulting in increased release of Cl- ions?

NSP4 of rotavirus