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11 Cards in this Set
- Front
- Back
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List some of the hormones released by the adrenal cortex |
-Glucocorticoids e.g. cortisol -Mineralocorticoids e.g aldosterone -Sex hormones e.g testosterone |
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What hormones are released from the adrenal medulla? |
-adrenaline and noradrenaline |
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What controls the adrenal cortex? |
-Adrenocorticotropic hormone (ACTH) is released from the anterior pituitary gland to control the release of hormones from the adrenal cortex |
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What is the function of the Glucocorticoids? |
-They promote the conversion of protein and lipids into carbohydrates |
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Which conditions see a rise in cortisol levels? |
-Obesity -schizophrenia -Osteoporosis -Diabetes -Anorexia -cardiovasular disease -Cancer -Aids -chronic fatigue -Depression -Anxiety |
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What is cushings syndrome? |
-It is the signs and symptoms associated with prolonged exposure to inappropriately high levels of the hormone cortisol |
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What does the Mnemonic CHUSHINGOID stand for? |
-Cataracts -Ulcers -Skin (stria, thinning, bruising) -Hypertension/ Hirsutism/hyperglycemia -Infections -necrosis -Glycosuria -Osteroporosis -Immunosupression -Diabetes |
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What are the clinical presentations of someone with cushings disease? |
-fat pads -Moon face -Red cheeks -Bruisability with ecchymossis -Think Skin -Striae -Pendulous abdomen -Poor muscle development -Poor wound healing |
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What two types of cushings disease are there? |
-Exogenous normal by drug treatment with gluccorticoids -Endogenous Cushings can be either pituitary dependent (80% of cases) or adrenal based (20% of cases)
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What are the clinical causes of endogenous cushings disease? |
-pituitary adenomas -Ectopoic acth Syndrome -Adrenal tumors |
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How can the Low dose dexamethasone Suppression test be used to diagnose someone with Cushings disease? |
-Dexmeth is a syntehcic glucocorticoid which acts at GCC receptor on the hypothalamus and pituitary to inhibit the secretion of CRH and ACTH, leading to a fall in the plasma cortisol level in healthy people. -There is only a slight drop in plasma cortisol levels in those with cushings disease |
