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5 Cards in this Set
- Front
- Back
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Rubella Virus
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Teratogenic if contracted in the first trimester.
Newborns present with classic triad of abnormalities: Heart Defects, Cataracts, Deafness. Do not administer rubella vaccine to any pregnant woman. |
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Infectious Agents During Pregnancy
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Rubella
Cytomegalovirus - most common viral infection in fetus. Herpes Simplex Virus (HSV) HIV - 13-39% risk to newborn from serum+ mother Varicella zoster (chickenpox) Toxoplasmosis - via cat feces Syphilis |
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Categories of Drug Teratogenesis
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Categories A-C: Fine to give.
Category D: Risk to the Fetus. Category X: Absolutely contraindicated in pregnancy. |
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Difference between penetrance and expressivity?
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Penetrance is the probability of any phenotypic expression.
Expressivity relates to the severity of the phenotype's expression. |
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Grouping by centromere Position
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metacentric - central, equal size arms
submetacentric - near center acrocentric - near one end telocentric - single arm (only in mice) |
