Test C Nbome

Front 1

does alcohol cause hypo/hyper thermia why?

Back 1

Uncoupling of oxidative phosphorylation, uncoupling proteins carry protons in the intermembranous space through the
inner mitochondrial membrane into the mitochondrial matrix without damaging the membrane.
(a) Bypass of ATP synthase causes decreased synthesis of A'l'P
(b) Examples—thermogenin (natural uncoupler in brown fat in newborns), dinitrophenol used in synthesizing nitroglycerin
(2) Heat normally used to synthesize ATP raises the core body temperature,
(a) There is a danger of developing hyperthermia with dinitrophenol,
(b) Thermogenin is useful in stabilizing body temperature in newborns.
Agents such as alcohol and salicylates act as mitochondrial toxins. They damage the inner
mitochondrial membrane, causing protons to move into the mitochondrial matrix. As with
dinitrophenol, hyperthermia is a common complication in alcohol and salicylate poisoning.

so if you were in a cold environment and drug you would get HYPOTHERMIA EVEN WORSE

Front 2

oxofloxacin

Back 2

floroquinolone---affects bones...CI in preg/children damage cartilate tendonitis, myalgias
inhibits DNA gyrase topo 2; bactericidal; do not take with antacids

gram - rods UTI/GI pseudomonas, neisseria GONORRHEA std

Front 3

tertiary syphilis

Back 3

floroquinolone---affects bones...CI in preg/children damage cartilate tendonitis, myalgias
inhibits DNA gyrase topo 2; bactericidal; do not take with antacids

gram - rods UTI/GI pseudomonas, neisseria GONORRHEA std

Front 4

treatment for wilson's disease, RA, chelator

Back 4

penicillamine

Front 5

treatment for copper, arsenic, gold lead

Back 5

penicillaimne chepllates "pennies"
lose taste

Front 6

direct bilirubin is?

Back 6

conjugated bilirubin so inc direct in jaundice cholestasia in urine;

Front 7

indirect bilirubin?

Back 7

unconjugated bilirubin

Front 8

oxidase + child w/ green discharge from ear gram - rods

Back 8

pseudomonas

other 2 things oxidase + are campylobacter and vibrio