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139 Cards in this Set

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What can bronchospasms present as?

Cough, chest pain, shortness of breath, fatigue with exertion, expiratory wheeze, and chest tightness

What are some things that can cause airway obstruction?

-presence of obstructing material (secretions, tumor or foreign body)


-Mucal thickening


-Contraction of smooth muscle (spasms)


-Extrinsic compression

What are differential causes of wheezing in children and infants?

-Asthma (especially with recurrent wheeze)


-Allergies


-GERD


-Infections (bronchiolitis, bronchitis, PNA)


-Obstructive sleep apnea


-Heart failure


_Bronchopulmonary dysplasia (Uncommon and can be seen in premature infants who have been on a ventilator)

A patient with recurrent respiratory infections needs to be evaluated for?

Immunodeficiencies (2 main types):


-Inherited


-Acquired (HIV)




-Make sure to refer to allergist/immunologist

What are signs and symptoms of an immunodeficiency

–8ormore new ear infections in a year


–Twoor more serious sinus infections


–Persistentoral candidiasis


–Twoor more months on antibiotics without improvement


–Theneed to clear infections with IV antibiotics–Recurrentpneumonia


–Failureto thrive


–Twoor more deep skin infections

If you are trying to diagnose asthma, what is important to ask in the history?

Asthma, eczema (atopic dermatitis) and allergies

What is the appearance of air hunger?

Sitting forward, trying to suck in air. Can be accompanied with nasal flaring.

What lung sound is associated with wheezing?

Prolonged expiratory phase

What will the lung sounds sound like with upper respiratory involvement?

Noisy breathing, snoring, stridor, and rhonchi

What will the lung sounds sound like with lower respiratory involvement?

-Presence of crackles/rales, rhonchi, wheezing, prolonged expiratory phase, and possible diminished breath sounds

In regards to pulse oximetry, what are different percentages for severity?

-Greater than 95% is WNL


-90 to 95% is moderate oxygen compromise


-Less than 90% severe lack of oxygen

When should you order a chest xray with wheezing?

Order a chest xray (PA and lateral) with the first episode of wheezing, other pulmonary disorders (PNA, CHF) and if the child is less than 1 year old with persistent wheezing.

What are some asthma changes that can be seen on xray?

-Can be normal xray findings


-May show hyperinflation of lungs


-Flattening of the diaphragm (associated with chronic inflammation and associated with accessory muscle use)


-Peribronchial thickening


-With or without atelectasis

When should you order a CT scan for sinusitis?

-Facial swelling


-Acute sinusitis unresponsive to 48 hours of antibiotics


-Toxic appearing child


-Recurring or chronic sinusitis


-Chronic unresponsive asthma

What are different kinds of allergy work up for asthma?

Skin testing (refer to allergist)


-ImmunoCap or RAST testing

When should you order a sweat test?

For suspected cystic fibrosis


-Measures the sodium in the skin


CF has >2.5 times the normal amount

What is the gold standard for diagnosing asthma in children?

Pulmonary function test-Spirometry is the gold standard for diagnosing asthma in children older than 4 years of age


Can be done:


-Done at the time of initial assessment


-Can be done after treatment is initiated and symptoms are stabilized to document attainment of near "normal" airway function


-During period of progressive or prolonged loss of asthma control


-At least every 1 to 2 years to assess maintenance

What is a peak expiratory flow?

-Diagnostic test


-Assesses control and evaluates effectiveness of beta agonist treatment in children 4 and up


-Use these values for the asthma action plan as the reference value


-Use during exacerbations to help determine the severity of the exacerbations and guide therapeutic decisions

What is the most likely cause of recurrent wheezing in children younger than 5 years?

Asthma

What is asthma characterized by?

Airway inflammation


airflow obstruction (caused by airway edema and mucus secretion and smooth muscles hyperplasia causes airway remodeling)


airway hyperresponsiveness (triggered by bronchospasms)

What is the etiology of asthma?

•Asthmais the leading serious chronic illness of children in the U.S.


•Themost common chronic disease of childhood


•Effectsmore than 5 percent of the U.S. population younger than 18 year


–In2006 an estimated 6.8 million children under 18 years were diagnosed withasthma


–Highestprevalence in children 5-17 years of age. Decreases with age


–Theprevalence has increased 75% over the past 20 years

What race is asthma prevalent?

25% higher among American Indian or Alaska children


-60% higher among blacks


-140% higher among Puerto Rican children relative to white children




-Could be due to access to medical care and more exposure to environmental factors

What are risk factors for persistent wheezing and predisposition to asthma in infants?

-Frequent symptoms in the first 12 months of life


-Eczema


-Elevated IgE levels


-Maternal history of asthma


-Maternal smoking

When should you suspect asthma in children?

URI trigger 85% of wheezing episodes


-3 or more episodes of otitis media


-PNA


-Atopic dermatitis


-Family history of asthma


-Laryngotracheitis


-Allergic rhinitis


-Any wheezing in the first 3 years


-Sinusitis and family history


-Recurrent wheezing in the first 6 years

What is the classic presentation of asthma?

Common asthma symptoms include: coughing, especially at night, wheezing, shortness of breath, chest tightness, pain or pressure, and fatigue with exertion

What is the unusual presentation of asthma?

-Chest tightness and difficulty breathing in the early morning hours


-Constant sighing


-Rapid breathing, fatigue, difficulty sleeping, anxiety, difficulty concentration, chronic dry, non productive cough

Aside from a chest xray and allergy testing, what else can you do to diagnose asthma?

Spirometry to demonstrate obstruction and assess reversibility


-Done in children older than 5 years old


-Reversibility is determined either by: an increase in FEV1 of more than or equal to 12% from baseline, increase of greater than or equal to 10% of predicted FEV1, and after inhalation of short acting bronchodilator

What are additional pulmonary studies for asthma?

Pulmonary function studies and broncho-provocation with methacholine, histamine, cold air or exercise challenge

What is pulmonary function studies?

–Measurementof lung volumes and evaluation of respiratory loops may be needed if there is aquestion about possible coexisting COPD, Vocal cord dysfunction or possiblecentral airway obstruction

What is broncho-provocation with methacholine, histamine, cold air or exercise challenge?

If asthma is suspected and spirometry is normal or near normal


-A positive test is consistent with asthma


-Negative test may be more helpful to rule out asthma

What 3 things are needed to diagnosis asthma?

-Episodic symptoms of airflow obstruction or airway hyperresponsiveness are present


-Airflow obstruction is at least partially reversible


-Alternative diagnoses are excluded

What is needed to determine if an infant or child needs intiation of long term control therapy?

If 4 or more episodes of wheezing in the past year that lasted more than 1 day and affected sleep and who have either 1 of the following:


-Parent with history of asthma


-Physician's diagnosis of atopic dermatitis


-Evidence of sensitization to aeroallergens




OR 2 of the following:


-Evidence of sensitization to fods


-Greater or equal 4% peripheral blood eosinophilia


-Wheezing apart from colds

If you are diagnosing a 5 year old or older with asthma, what would they demonstrate with a spirometry?

-Demonstrate obstruction and assess reversibility


-Reversibility is determined either by: an increase in FEV1 or greater than or equal to 10% of predicted FEV1


-After inhalation of short acting bronchodilator


**Spirometry is needed to establish a diagnosis of asthma**

According to the NHLBI key indicators for considering a diagnosis of asthma, what do you need a history of for asthma?

History of:


-Cough (worse at night), recurrent wheeze, recurrent difficulty in breathing, recurrent chest tightness


-Symptoms occur or worsen in the presence of (exercise, viral infection, animals, house dust, changes in weather, laughing or crying hard, menstrual cycles)


-Symptoms occur or worsen at night (awakens the patient)

What is needed to determine asthma control?

-Determine the asthma severity (before treatment)


-Assess asthma control (goal is the lowest level of treatment needed to maintain control)


-Classifying severity of asthma exacerbation (mild, moderate, severe, and respiratory arrest immanent)

Describe Step 1 Mild Intermittent for a 0 to 4 year old

Daytime S/S: Symptoms are less > or equal to 2 per week, asymptomatic and normal PEF between exacerbations, requires SABA 2 days a week. No interference with normal activity


Night time S/S: 0

Describe Step 2 Mild Persistent for a 0 to 4 year old

Daytime S/S: Symptoms >2 per week but <1 time per day. Requires SABA >2 days per week but <1 per day. Exacerbations may affect activity


Night time S/S: 1 to 2 times a month

Describe Step 3 Moderate Persistent for 0 to 4 year old.

Daytime S/S: daily symptoms, daily use of inhaled SABA. Some limitations. Exacerbations affect activity >2 per week. May last days.


Night time S/S: 3 to 4 times a month

Describe Step 4 Severe Persistent for 0 to 4 year old.

Daytime S/S: Throughout the day. Requires SABA several times a day. Extremely limited physical activity. Frequent exacerbations


Night time: >1 time a week


Lung function: FEV1 <60% predicted

Describe Step 1 Mild Intermittent in 5 to 11 year old.

Daytime S/S: Symptomsless than or equal to 2 per weekAsymptomatic and normal PEF betweenexacerbationsRequires SABA(Short acting beta2agonists) 2 days per weekNo interference with normalactivity


Night time: <2 or equal to 2 times a month


Lung function: FEV1 >80% predicted. Normal FEV1 between exacerbations

Describe Step 2 Mild Persistent in 5 to 11 year old.

Daytime: Symptoms >2/wk but <1time /dayRequiresSABA >2days/wk. but <1/dayExacerbationsmay affect activity


Night time: 3 to 4 times/month


Lung function: FEV1 >80% predicted

Describe Step 3 moderate persistent in 5 to 11 year olds.

Daytime: Daily symptoms, daily use of SABA, some limitation of normal activity


Night time: >1 time a week but not nightly


Lung function: FEV 60-80% predicted

Describe Step 4 Severe persistent in 5 to 11 year olds.

Daytime: Throughout the dayRequires SABA several times a dayExtremely limited physical activityFrequent exacerbations


NIght time: Often 7 times/week


Lung function: FEV1 <60% predicted

Describe the asthma control and adjusting therapy in a 0 to 4 year old if well controlled.

Symptoms: < or equal to 2days/week


Night time wakening: < or equal to 1 time/month


Activity interference: None


SABA: < or equal to 2 days/week


PO steroids: 0-1 per year


Recommended action: Maintain current treatment and follow up every 1 to 6 months. Consider step down if controlled for 3 months

Describe the asthma control and adjusting therapy in a 0 to 4 year old if not well controlled.

Symptoms: >2 days/ week


Night time waking: > 1 time per month


Activity interference: Some limitation


SABA: >2 days per week


PO steroids: 2 to 3 times per year


Recommended action: Step up(1 step) and reevaluate in 2-6 weeks.If noclear benefit in 4 -6 wks, consider alternative diagnoses oradjusting therapy

Describe the asthma control and adjusting therapy in a 0 to 4 year old if poorly controlled.

Symptoms: throughout the day


Night time waking: >1 time per week


Activity interference: Extremely limited


SABA: Several times per day


PO steroids: >3 per year


Recommended action: Consider short course of oral systemiccorticosteroidsStep up (1-2 steps) and reevaluate in 2weeks. If no clear benefit in 4-6 weeks consider a different diagnosis

Describe the asthma control and adjusting therapy in a 5 to 11 year old if well controlled.

Symptoms: < or equal to 2 days/week


Night time waking: < or equal to 1 time/month


SABA: < or equal to 2 days/week


Lung function: 80% predicted or personal best


PO steroids: 0 to 1 per year


Recommended action: Maintain current step. follow up every 1 to 6 months. Step down if well controlled for at least 3 months

Describe the asthma control and adjusting therapy in a 5 to 11 year old if not well controlled.

Symptoms: >2 days/week or multiple times on < than or equal to 2 days/month


Night time waking: > or equal to 2 times/month


SABA: > or equal to 2 days/week


Lung function: 60-80%


PO steroids: > or equal to 2 per year


Recommended action: Step up at least 1 step, reevaluate in 2 to 6 weeks. Use alternative treatment for side effects

Describe the asthma control and adjusting therapy in a 5 to 11 year old if very poorly controlled.

Symptoms: Throughout the day


Night time waking: >2 times per week


SABA: Several times per day


Lung function: <60%


PO steroids: > or equal to 2 per year


Recommended action: Consider short burst of systemic corticosteroids. Step up 1 to 2 and reevaluate in 2 weeks

If a patient has mild classification for the severity of asthma exacerbation, how would you describe it?

Symptoms can happen while walking and can lie down


Talks in: Sentences


Alertness: May be agitated


Respiratory rate: Increased


Accessory muscle use: Usually not


Wheezing: Moderate often only at end expiratory


Pulse: Normal


PEF: > 70%


PaO2: Normal


PCO2: <42mmhG


Pulse ox: >95%

If a patient has moderate classification for the severity of asthma exacerbation, how you would describe it?

Symptoms: While at rest. Infants will have a soft, short cry and feed less. Prefers to sit


Talks in: Phrases


Alertness: Usually agitated


Respiratory rate: Increased


Accessory muscle use: Common


Wheezing: Loud, exhalation


Pulse: Increased


PEF: 40 to 69%


PaO2: >60mm Hg


PCO2: <42mmHg


Pulse Ox: 90-95%

If a patient has severe classification for the severity of asthma exacerbation, how would you describe it?

Symptoms: While at rest. Infant stops feeding and sits upright


Talks in: Words


Alertness: Usually agitated


Respiratory rate: Increased


Accessory Muscle use: Usually


Wheezing: Loud, inhalation, and exhalation


Pulse: Increased


PEF: <40%


PaO2: <60mmHg


PCO2: >42mmhg (possible respiratory failure)


Pulse ox: <90%

What is the goals of treatment for asthma?

•Chroniccontrol


•Maintainnormal activity levels and exercise•Maintainnear normal pulmonary function•Preventacute episodes of asthma


•Minimizeemergency department visits and hospitalizations


•Avoidadverse effects of asthma medications

What are some short acting beta agonists? (SABA)

-Albuterol (ProAir, proventil, ventolin)


--Regular use on a daily basis means poor control


-Levalbuterol (HFA, Xopenex)



When you need quick control, what can you prescribe on top of the albuterol inhaler? What is the dosage?

Methlprednisolone


Short burt of 1-2mg/kg/day divided to every day to twice a day for 3 to 10 days until peak flow is 70%

What are some inhaled corticosteroid medications for long term control?

Mometasone, budesonide, fluticasone, beclomethasone, and ciclesonide

What are examples of inhaled corticosteroids + LABA medications for long term control?

Fluticasone/Salmeterol


Budesonide/formeterol


Mometasone/formeterol

Describe the stepwise method and what medications are included in the stepwise method for 0 to 4 year olds.

Step 1: SABA PRN


Step 2: Low dose ICS + cromolyn or moteleukast


Step 3: Medium dose ICS


Step 4: Medium dose ICS + LABA or monteleukast


Step 5: High dose ICS + Laba or monteleukast


Step 6: High dose ICS + LABA or monteleukast + oral corticosteroid

What can signify the need to step up treatment in any age group?

Frequent use of SABA may indicate the need to step up treatment




Use of SABA >2 days a week (usually means poor control in 5 to 11 year olds)

Describe the stepwise method and what medications are included in the stepwise method for 5 to 11 year olds.

Step 1: SABA PRN


Step 2: Low dose ICS +cromolyn or singulair


Step 3: Low dose ICS + LABA or low dose ICS with either singular, theophylline, or medium dose ICS


Step 4: Medium dose ICS + LABA or Medium dose ICS + singular or theophylline


Step 5: High dose ICS + LABA or High dose ICS + singulair or theophylline


Step 6: High dose ICS + LABA + oral steroid

Describe the stepwise method and what medications are included in the stepwise method for 12 years and older.

Step 1: SABA PRN


Step 2: Low dose ICS or cromolyn, Singulair


Step 3: Low dose ICS plus LABA or Low dose ICS plus singular, theophylline, or zileuton


Step 4: Medium dose ICS + LABA or Medium dose ICS + singulair, theophylline, or zileuton


Step 5: High dose ICS + LABA and consider omalizumab


Step 6: High dose ICS + LABA+ steroid

How long should you follow up with an asthmatic patient?

Follow up monthly until controlled then every 6 months. If stable after 3 months, try to reduce therapy by 25 to 50%

What is allergic rhinitis and how is it diagnosed?

Inflammation of the nasal epithelium


-Second most common atopic disorder (asthma #1)


-Diagnosed in presence of rhinorrhea, nasal pruritis, congestion, and sneezing

What is the subjective data for allergic rhinitis?

Nasal congestion, mouth breathing, snoring, nasally speech, itchy nose, palate, pharynx, and eyes, sneezing, hoarseness, rhinorrhea, red eyes, postnasal discharge, and night cough

Describe some objective data for allergic rhinitis in the eyes, ears, mouth and nose.

Eyes: Dennie lines and morgan fold, cobble stone appearance palpebral conjunctiva


Ears: asses for otitis media and serous otitis


Nose: Assess for pale to purplish color and edema (boggy) nasal mucosa membranes, clear thin watery nasal discharge, will have nasal crease: horizontal crease across the lower third of nose, presence of nasal polyps


Mouth: Cobblestone appearance of the pharynx, mouth breather and assess for tonsilar hypertrophy



What is Dennie lines or Morgan fold?

Extra groove in lower eyelid, conjunctivitis, and dark circles

How is allergic rhinitis diagnosed?

Characteristic symptoms and clinical findings


-History of atopy in child or family


-Presence of eosinophils on nasal smear


-Referrals for skin allergy testing


-Serologic testing for IgE antibody to specific allergens (RAST, ImmunoCAP test)

How do you manage allergic rhinitis?

-Avoidance of the offending allergen


-Oral antihistamines (first generation: sedating benadryl and second generation: Nonsedating: Loratidine, cetirizine)


-Nasal antihistamines


-Nasal irrigations


-Leukotrienes: Singular


-Intranasal corticosteroids (Flonase, Nasonex)

What is the best nasal irrigation to use?

1/4 teaspoon of salt in 8 ounces of water


-Washes away irritants


-Moistens the mucosa

What should you be cautious with when using nasal decongestants?

-Helpful to relieve nasal congestion but short term use only.


-Can cause rebound rhinorrhea if used for more than 3 to 5 days


-Children younger than 2 years old should not be given decongestants

What is the most common upper respiratory infection in children?

The common cold: Acute viral rhinitis


-Children have 6 to 12 colds per year


-30 to 40% are caused by rhinoviruses


-Average duration is 1 week

What are subjective data for upper respiratory infection (the cold).

-Sudden onset of clear or mucoid rhinorrhea


-Nasal congestion


-Sneezing


-Sore throat


-Cough


-Possible fever (especially in children less than 5 years old)

What are some objective data for upper respiratory infection (the cold)?

Nose, throat, and tympanic membranes may appear red and inflamed



What other objective data for other types of viruses? (Epstein-Barr virus, Adenovirus, Enteroviruses, herpesvirus)

Epstein-Barr: possible exudate on tonsils


Adenovirus: possible exudate on tonsils with cervical lymphadenopathy


Enteroviruses: Possible vesicles or ulcers on the tonsillar pillars


Herpesvirus: Ulcers anteriorly and cervical lymphadenopathy

How do you treat upper respiratory infections?

-Acetaminophen or ibuprofen for fever or pain.


-Humidification for relief of congestion and cough


-Nasal saline drops with suction to relieve mucous


-Avoid OTC medication in children under 4 years


-Antihistamines do not work in relieving cold symptoms




-Fluids (water)


-Humidification (clean properly every 3 days)


-Bulb syringe (gentle nasal irrigation)


-Normal saline nasal drops

What over the counter medications have been withdrawn from children?

Antihistamines


Antitussives (dextromethorphan)


Expectorant (guaifenesin)


Decongestant (pseduophedrine)

What are signs and symptoms of respiratory distress?

-Tachypnea


-Drooling


-Grunting respirations (Ominous sign of impending respiratory failure)


-Tripod position (Upright, leaning slightly forward, mouth open and with head, neck and jaw thrust forward)


-Nasal flaring


-Use of accessory muscles


-Increased restlessness


-Apprehension


-Agitation


-Cyanosis


-Drowsiness to coma

What are 3 symptoms needed to diagnose rhinosinusitis?

-Purulent nasal discharge


-Nasal obstruction


-Facial pain, pressure or fullness lasting between 10 days and 4 weeks

What are common bacteria of rhinosinusitis?

S. pneumoniae, H. influenzae, and Moraxella catarrhalis

What are signs and symptoms of rhinosinusitis?

Primary symptoms: purulent rhinorrhea, facial pain, and nasal obstruction


Suggestive signs and symptoms: Headache, fever, fatigue, maxillary dental pain, cough, decreased ability to smell, ear pressure or fullness


Additional key issues: Cough worse at night, periorbital cellulits, and occasional malodorous breath or ears feel full

How do you diagnose rhinosinusitis?

Usually diagnosed without imaging based on signs, symptoms, and clinical findings


-CT Scan is usually done if facial swelling and acute rhinosinusitis is unresponsive to 48 hours of antibiotics, child has a toxic apperance, chronic or recurrent rhinosinusitis, and chronic unresponsive asthma

What is the management for acute rhinosinusitis?

-Most acute rhinosinusitis resolve without antibiotics in about 4 weeks


-Amoxicillin (80 to 90mg/kg/day)


-Augmentin, Cefpodoxime




If allergic to amoxicillin, can use azithromycin

What is chronic sinusitis?

Symptoms persisting for at least 12 weeks


-Risk factors: anatomic blockage, irritant and allergen exposure, defects in mucocilliary function, immunodeficiency, and chronic infection with bacterial viruses or fungi

What is stridor and What are some diseases that can cause stridor?

-High pitched wheezy sound in the upper airway


-Epiglottitis, laryngotracheobronchitis "infectious croup", bacterial tracheitis, diptheria, and foreign body

What is epiglottitis and who is at risk?

-Acute inflammation of the epiglottis and the supraglottic larynx caused by the Haemophilus influenzae bacteria, neisseria meningitides or streptococcus.


-CHildren between 1 and 5 years old affected




-Rare event secondary to the Haemophilus Influenzae conjugate vaccine

What are signs and symptoms of epiglottitis?

–Suddenescalating high fever


–dysphagia and drooling


–muffled voice and sore throat


–inspiratoryretractions, cyanosis and soft stridor


–“looksill”


–Mayprogress to total airway obstruction and respiratory arrest

How do you diagnose epiglottitis?

-Direct visualization of the epiglottis

-Epiglottis will be cherry red and swollen

How do you treat epiglottis?

-Endotracheal intubation in children


-Blood cultures


-IV antibiotics for 2 to 3 days follow by 10 day course of oral antibiotics


-Cephalosporin to cover H. influenzae and Streptococcus species

What is laryngotracheitis (Croup)?

-Swelling and erythema of the lateral walls of the trachea below the vocal cords


-Results in rapid, acute upper airway obstruction at the larynx


-Harsh, barking cough




Effects children less than 6 years old. Most common between 6 and 36 months

What causes croup?

Viral


Parainfluenza type 1 is the most common cause


Can also be caused by influenza, metaphenumovirus, adenovirus, and rhinovirus


-Incubation period is 3 to 6 days and lasts 5 days

What is the clinical presentation of croup?

-Recent history of URI before onset of stridor


-Fever within the first 24 hours


-Intermittent stridor (mild to moderate "barky cough")


-Symptoms worse at night


-Gradual onset of symptoms 2 to 3 days


-May or may not have sore throat


-Improvement within a few days if you have viral croup

What will the physical exam of croup look like?

•Slightdyspnea, tachypnea and retractions•Mild,brassy or barking cough


•Stridor–Highpitched, harsh sound from turbulent air flow, inspiratory


•Fever,low grade or elevated


•Substernal andchest wall retraction in severe case


•Prolongedinspiration

How is croup diagnosed?

-Based on history and clinical findings


-X ray of neck and chest


-Classic pattern: subglottic narrowing will show "steeple sign" on posterioranterior views

What are some differential diagnosis for croup?

-Epiglottitis


-Acute spasmodic croup (no signs of infection)


-Foreign body aspiration


-Retropharyngeal abscess


-Extrinsic compression from tumors

How do you manage croup?

-Humidified air


-Cold, night air is helpful to decrease inflammation


-Nebulized epi (short term benefits for 2 hours, can lead to rebound swelling several hours later, and close cadriorespiratory monitoring)


-Corticosteroids (helpful to decrease inflammation, also short term. Dexamethasone 0.6mg/kg or Pulmicort respules nebulizer)


-Cold medication is not helpful

When should you consider hospitalization with croup?

Respiratory distress


-Rate between >60 breaths per minute


-Exhibiting stridor at rest


-Temperature greater than 102.2F

What is bacterial tracheitis (membranous croup)?

-Acute bacterial infection of the upper airway

-Does not involve the epiglottis


-Usually seen between the ages of 3 and 10


-Usually follow an URI


-Begins with croup episode but becomes infected with S. aureus (most common), H. influenzae or M. catarrhalis



What are clinical findings to bacterial tracheitis?

–Brassycough, High fever (greater than 102 F)


–Rapidlydeteriorates


–Copiouspurulent sputum


–Looksill


–Slowercourse than Epiglottis, normal appearing epiglottis.




–CBC: elevated WBC with a left shift

How do you manage bacterial tracheitis?

–Hospitalization


–Intubationor tracheostomy to bypass tracheal swelling


–Oxygen


–Antibioticsto cover S. aureus


–Mostchildren become afebrile in 48 to 72 hours

What is foreign body aspiration and the difference between a large foreign body versus small objects?

-Onset of sudden episode of coughing without the signs of respiratory infection


-Large foreign body can occlude the upper airway and cause suffocation


-Small objects in the lower respiratory tract may not produce symptoms for days to weeks




-Common causes: hot dogs, peanuts, small coins, popcorn, hard candy, and small toys

What are some clinical findings to foreign body aspiration?

–Chokingalong with inability to vocalize or cough


–Cyanosiswith marked distress


–Drooling,stridor


–Abilityto vocalize (partial obstruction)


–Hemoptysis,dyspnea, wheezing


-Wheezingthat does not respond to bronchodilators

What is the treatment for foreign body aspiration in the upper airway and lower airway?

Upper airway: Allow the choking patient to continue to cough to remove the foreign body or use the AHA recommendations (5 back blows, 5 chest compressions, etc.)




Lower airway: Bronchoscopy to remove the object

How will you diagnose foreign body aspiration?

Chest x-ray (not as helpful)


-Chest fluroscopy


-Bronchoscopy

When does acute bronchitis occur?

Most commonly occurs after a viral infection (rhinovirus, RSV, influenza, parainfluenza, and adenovirus

What is chronic bronchitis?

Productive cough lasting more than 3 months. Usually related to asthma, allergies, CF, and cigarette smoking

What are the symptoms of bronchitis?

-Mild URI symptoms, rhinitis, and pharyngitis


-Dry hacking cough that begins 3 to 4 days after onset of rhinitis, cough becomes more productive after a few days, wheezing


-Older patients c/o chest pain which worsens with coughing


-Younger children may have post-tussive vomiting


-Normal temperature or low grade fever

What are some differential diagnosis for bronchitis and how do you rule it out?

-Asthma: patten of wheeze, no fever


-Bronchiectasis: Recurrent pulmonary infections, irritability, poor growth


-Congenital heart disease: heart murmur, signs of CHF, and poor growth


-Sinusitis: Purulent rhinitis lasting weeks, headache, and facial dental pain


-Foreign body aspiration


-GERD: barium swallow shows reflux into esophagus

How do you diagnose bronchitis?

Chest xray will be normal


CBC: Shows elevated neutrophils (Bacterial infection)


C reactive protein: Elevated (Bacterial infection)

How do you treat bronchitis?

-Supportive care


-Antibiotics


-Humidified air


-Chest physiotherapy (if productive cough and coarse crackles)

When should you avoid cough suppressants?

Avoid cough suppressants in children with a productive cough

What kind of antibiotics would you use to treat bronchitis?

Bronchitis is usually viral, but if not:


Azithromycin for 5 days or erythromycin for 14 days

When should you follow up with bronchitis?

If they are coughing for 2 weeks


If the cough worsens


If the fever persists or worsens


If in respiratory distress

What is bronchiolitis?

Viral illness that lasts 1 to 3 days and that causes inflammation leading to obstruction of the small respiratory airways.


-Leading cause of hospitalizations for infants


-Can be caused by RSV or other viruses



What is the clinical presentation of bronchiolitis?

Initially: URI


Gradual development of respiratory distress


-Noisy, raspy breathing with wheezing


-Low grade to moderate fever


-Decreased appetite




Infants may just show apnea

What are the physical findings of bronchiolitis?

-Paroxysmal wheezing (usually at night)


-Crackles


-High respiratory rate(60-80 breaths per minute)


-Signs of respiratory distress (nasal flaring, grunting, retractions, cyanosis, prolonged expiration)

What are diagnostic tests for bronchiolitis?

Chest x-ray to rule out pneumonia


-RSV wash for rapid testing


-Viral cultures of nasal washing to confirm other viruses

How do you treat bronchiolitis?

Supportive care


-Increase fluids (pedialyte, breast milk, or formula) to prevent dehydration


-Humidified air to loosen sticky mucus


-Avoid smoke exposure


-Antipyretics for fever


-Elevate of the child to a sitting position at a 30 to 40 degree angle


-Can try nebulizer



What is pneumonia?

Lower respiratory tract infection


-Consolidation of the alveolar spaces involving airways and parenchyma


-Bacterial PNA is caused by streptococcus


-Mycoplasma PNA causes "walking" PNA (atypical)



When does viral pneumonia occur in a child?

-Most common between 2 and 3 years old

When does bacterial pneumonia occur in a child?

More common in children over 5 years old


-Mycoplasma PNA is leading cause in school age children and adolescents

What are the symptoms of viral pneumonia?

Onset may be acute or gradual, progresses more slowly


-Nasal congestion, coryza, and cough


-Hoarseness, wheezing, rapid/shallow respirations


-Lower respiratory S/S develop slowly


-Can have fever


-Nontoxic apperance

What are the symptoms of bacterial pneumonia in an infant? (S.pneumonia)

Initially: mild URI, unilateral conjunctivitis, abrupt fever to 104F, mild cough, diarrhea, vomiting


Progresses: restlessness, apprehension, nasal flaring, rapid shallow respirations, grunting, abdominal distention, cough may be absent

What are the symptoms of bacterial pneumonia in older children and adolescents? (S.pneumonia)

-Onset abrupt with rigors and fever 102-104


-Appears ill


-Headache


-Anorexia, nausea, vomiting, diarrhea, abdominal pain


-Dyspnea, pleuritic pain, cough


-Alternating restlessness and drowsiness

What are the symptoms of mycoplama pneumoniae? (walking pneumonia)

-Slow onset


-Malaise, transient arthritis


-Persistent dry, hacking cough


-Sore throat often followed by hoarseness


-Low grade temperature and chills

What are objective findings to viral pneumonia?

-Can be non-toxic appearing


-Tachypnea, cough, diffuse bilateral wheezing, decreased breath sounds


-Supresternal, intercostal, substernal retractions


-Cyanosis

What are objective findings to bacterial S. pneumoniae in infants?

-Tachypnea, nasal flaring, grunitng, retractions, diminished breath sounds, crackles, wheezing

-Fever, tachycardia, air hunger, cyanosis


What are objective findings to bacterial S. pneumoniae in older children ?

-Diminished breath sounds over the affted lung


-Dullness to percussion over consolidation


-Productive cough


-bloody, rust tinged sputum


-crackles, wheezing, splinting of respirations on affected side


-Fever, nuchal rigidity


-Drowsiness, restlessness


-Respiratory distress

What are objective findings to bacterial M. pneumoniae?

-Fever


-Diminished breath sounds, coarse, harsh breath sounds, and fine crackles


-May have a macular rash, erythematous macular rash


-Cervical lymphadenopathy, conjunctivitis, and otitis media

What will the physical exam show for pneumonia in general?

-Elevated respiratory rate, accessory muscle use, wheeze or crackles, retractions, tachypnea, decreased tactile and vocal fremitus, diminished breath sounds


-Dullness plus fine and crackling rales on the affected side



Describe the cough and sputum color in bacterial pneumoniae

Dry, hacking and productive cough


-Rust color sputum or bloody sputum

What are the physical findings in atypical pneumonia?

URI symptoms, low grade fever, dry cough with scant sputum


-Minimal changes or harsh breath sounds and rhonchi


-Rhinorrhea not common

How do you diagnose pneumonia?

Viral: CXR will show diffuse infiltrates


Bacterial: blood cultures, WBC, S pneumoniae will show lobar consolidation and S. aureus will show bronchopneumonia


Atypical: Interstitial infiltrates, patchy inflammatory changes

What is the treatment for bacterial pneumonia?

Infants younger than 4 to 6 months are usually hospitalized


-Acetaminophen


-Antibiotic treatment: Amoxicillin or augmentin, azithromycin

What is the treatment for atypical pneumonia (M. pneumoniae)?

Erythrmycin or azithromycin


Acetaminophen

What is cystic fibrosis?

-Autosomal recessive genetic multisystem disorder that affects exocrine function


-Defective gene results in unusually thick, sticky mucus that obstructs glands, ducts, damages tissues (pulmonary, GI, endocrine/metabolic, and reproductive)


-Obstructs the pancreas and stops natural enzymes from helping the body break down and absorb nutrients


-Clogs the lungs and leads to infection

What are signs and symptoms of cystic fibrosis?

-Salty, tasty skin


-Persistent coughing


-Frequent lung infections


-Wheezing or shortness of breath


-Poor growth/weight gain in spite of a good appetite


-Frequent greasy, bulky stools or difficulty in bowel movements

How and what are the results of a diagnostic test for cystic fibrosis?

-Positive sweat test (Measures the amount of chloride in the sweat)


-Sputum culture


-Pulmonary functions test


-Liver function test


-Stool 72 hour fecal fat test


-Chest X-ray/CT Scan

What is the most common cause of bronchiectasis in children?

Cystic fibrosis

How do you manage CF?

-Supportive care


-Organ transplant if severe


-Medications:


-Bronchodilators (Albuterol, ipratropium)


-Nebulized hypertonic saline


-Oral corticosteroids


-Antibiotics to treat respiratory infections


-Pancreatic enzyme supplements