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139 Cards in this Set

  • Front
  • Back
How does MgSO4 work on preeclamptic pts
Elevates seizure threshold, a positive side effect is that it also decreases blood pressure and increases uterine blood flow
What is the dose for MgSO4?
4gm loading dose followed by
1-2gm/hr infusion
What is the therapeutic level for MgSO4?
a) 1-3mg/L
b) 3-5 mg/L
c) 6-8mg/L
d) 10-12mg/L
6-8mg/L
If MgSO4 serum level is 12-14mg/L what type of symptoms would you expect to see?
a) ventilatory insufficiency
b) cardiac asystole
c) progressive respiratory depression
d) positive patellar reflexes
e) absent patellar reflexes
progressive respiratory depression

absent patellar reflexes
If MgSO4 serum level is 22-24mg/L what type of symptoms would you expect to see?
a) ventilatory insufficiency
b) cardiac asystole
c) progressive respiratory depression
d) positive patellar reflexes
e) absent patellar reflexes
ventilatory insufficiency

cardiac asystole

absent patellar reflexes
At what MgSO4 serum level do patellar reflexes disappear?
a) 6-8mg/L
b) 1-2mg/L
c) 9-10mg/L
d) immediately after giving loading dose
9-10mg/L
Maternal O2-Hb curve
a) shifted to the left
b) shifted to the right
c) high affinity for O2
d) low affinity for O2
shifted to the right

low affinity for O2 (this allow O2 to be shunted to the baby)
Fetal O2-Hb curve
a) shifted to the left
b) shifted to the right
c) high affinity for O2
d) low affinity for O2
shifted to the left

high affinity for O2
Right shift on O2-Hb curve
a) high O2 binding
b) low O2 binding
c) low pH
d) low temp
e) high temp
f) high 2-3 DPG
g) low 2-3 DPG
low O2 binding
low pH
high temp
high 2-3 DPG
Left shift on O2-Hb curve
a) high O2 binding
b) low O2 binding
c) high pH
d) low temp
e) high temp
f) high 2-3 DPG
g) low 2-3 DPG
high O2 binding
high pH
low temp
low 2-3 DPG
What dose of Thiopental will decrease uterine blood flow?
a dose > 4mg/kg
What dose of Ketamine will decrease uterine blood flow?
a dose >2mg/kg
Inhalation agents with what MAC will cause decrease uterine blood flow
any MAC GREATER than 0.5 will decrease uterine blood flow
What do MgSO4, Ntg, Hydralazine do to uterine blood flow increase/decrease it
increase it
When does cardiac output peak in pregnant woman
a) early 1st stage of labor
b) late 1st stage
c) second stage
d) post-partum period
Post partum period increases by 80%
in the first 48hrs
When does cardiac output return to normal in a post partum woman?
2 weeks after delivery
When is a pregnant woman considered to have a full stomach?
at 15 weeks and beyond
Pregnant women have a lower pseudocholinesterase level, when is it decreased the most?
a) during labor
b) 1 day post partum
c) 3 days post partum
3 days post partum, it is decreased by 60%!
Some causes of uterine rupture include
a) previous C-section
b) polyhydraminos
c) multiple pregnancies
d) large baby
previous C-section
polyhydraminos
multiple pregnancies
large baby
When placing an epidural needle is the bevel up or down?
The needle is parallel and bevel up

DECREASES RISK OF PDPH
When you add bicarb to a local anesthetic what does it do?
a) increase intensity
b) increase duration
c) increase onset
increase onset it does this by changing the PKA of the LA bringing it closer to physiologic pH
When epinephrine is added to a local anesthetic what does it do?
a) increase intensity
b) increase duration
c) increase onset
increase intensity

increase duration

this related to lipid solubility
When is a pregnant woman most likely to have fluid overload?
post-delivery because of redistribution
Why would you not want to use Epi in a test dose on a patient with Eisengmeyer syndrome?
a) due to the tachycardia that can happen with the epi
b) due to the increase in pulmonary vascular resistance that can be caused
due to the increase in pulmonary vascular resistance that can be caused

Pt's with this disease already have
Pulm HTN and this could exacerbate it.

DON'T USE EPI ON ANY PT WITH A SHUNT!
Why would you not want to use Epi in a test dose in a patient with a cardiac stenotic lesion?
a) due to the tachycardia that can happen with the epi
b) due to the increase in pulmonary vascular resistance that can be caused
due to the tachycardia that can happen with the epi
You need to relax a uterus for what reasons
a) breech/twins
b) uterine tetanus
c) post partum hemorrhage
d) inverted uterus
breech/twins
uterine tetanus
post partum hemorrhage (because may need to manipulate uterus if retained placenta or inverted uterus)
inverted uterus
What MAC would be used in the case of uterine atony?
a) 0.5
b) > 1 MAC
> 1 MAC
What drug is used for uterine atony? What is the dose?
NTG 50-100mcg
With general anesthesia besides airway, what is the second most common risk/adverse outcome in a pregnant woman?
Aspiration
Signs & symptoms of aspiration include
a) decreased PaO2
b) increased pressures
c) wheezing
d) cyanosis
e) increased HR
f) Increased BP
decreased PaO2
increased pressures
wheezing
cyanosis
increased HR
Increased BP (initially, then will decrease)
What is the treatment for aspiration? (choose all that apply)
a) Suction
b) Positive Pressure
c) antibiotics
d) steroids
e) albuterol
Suction
Positive Pressure
albuterol

NO steroids or antibiotics, study show they may actually cause more harm than good
During anesthesia, when does the pregnant woman have the highest risk of aspiration?
a) on intubation
b) after delivery
c) at extubation
after delivery
at extubation
Which of the following meds can cause increased bleeding in a pregnant woman
a) Ca Channel blockers
b) NTG
c) Nipride
d) B-blockers
Ca Channel blockers (blocks uterine contraction d/t decreased Calcium)
NTG (vasodilation)
Nipride (vasodilation)
What is the differential diagnosis for a post dural puncture headache?
POSITION! If patient lays down & headache goes away IT IS A PDPH!
when sitting up the decrease in CSF causes sagging of ventricles which causes the headache
What are the signs & symptoms of a PDPH
a) fever
b) headache
c) neck pain
d) nausea
headache

neck pain
Most effective way to treat a PDPH?
Epidural blood patch
Uterine rupture
a) pre-term hemorrhage
b) intra-partum hemorrhage
c) post-partum hemorrhage
can be found in all
pre-term hemorrhage
intra-partum hemorrhage
post-partum hemorrhage
Placenta abruption
a) painful bleeding
b) non-painful bleeding
c) pre-partum hemorrhage
d) intra-partum rupture
painful bleeding

pre-partum hemorrhage
Placenta previa
a) painful bleeding
b) non-painful bleeding
c) pre-partum hemorrhage
d) intra-partum rupture
non-painful bleeding

pre-partum hemorrhage
Post-partum hemmorhage
a) uterine atony
b) placenta acreta
c) retained placenta
d) placenta previa
uterine atony
placenta acreta
retained placenta
Top 4 reasons for pregnancy related deaths according to WHO
a) Hemorrhage
b) other direct causes
c) HTN disorders
d) Embolism
e) abortion
Hemorrhage
other direct causes
HTN disorders
Embolism
Top 4 reasons for pregnancy related deaths in NC 1995-1999
a) cardiomyopathy
b) hemorrhage
c) PIH
d) CVA
e) Amniotic fluid embolism
#1 cardiomyopathy
#2 hemorrhage
#3 PIH
#4 CVA
T/F there is a huge disparity in the number of pregnancy related deaths related to race/socioeconomics
True!
While there has been a decrease in birth related problems r/t regional anesthesia, ASA closed claims courts have seen a huge shift in what?
The number of claims while they are related to regional anesthesia are trivial reasons like, headache and discomfort
The number one reason for women to die in the world
a) car accidents
b) cardiomyopathy
c) childbirth
d) CVA
childbirth
Pregnant women with cardiomyopathy
a) C-section is always indicated
b) vaginal birth is preferred
c) should be on anticoagulants
d) should be induced early
e) do not have to be induced early
vaginal birth is preferred (with passive second stage delivery)
should be on anticoagulants
do not have to be induced early
What drugs should be avoided in pregnant women
a) ACEI's
b) amiodorone
c) verapamil
d) propanolol
e) anticoagulants
ACEI's
amiodorone
verapamil
When delivering a baby of a mother with cardiomyopathy what is important to remember about the 2nd stage of labor?
it should be PASSIVE labor, where the mom is NOT allowed to push (Valsalva increases ventricular work) and the baby is delivered with forceps
Your pregnant mother has aortic stenosis which is the best option for a regional anesthetic
a) Continuous spinal
b) Epidural
c) CSE
Epidural because preload is not compromised like it is with a spinal technique
Definition of peripartum cardiomyopathy includes
a) ejection fraction <45%
b) development of cardiac failure in the last month or within 5 months
c) absence of identifiable cause for the heart failure
d) absence of recognizable heart disease before last month of pregnancy
ejection fraction <45%
development of cardiac failure in the last month or within 5 months
absence of identifiable cause for the heart failure
absence of recognizable heart disease before last month of pregnancy
Why is retained placenta the most common cause of serious blood loss?
Because of the uterine atony associated with it! Uterus will NOT contract if it is not COMPLETELY empty!
Which pregnant patients would it be important to get coags on
a) abruptio
b) IUFD
c) Uterine rupture
d) one who is on Heparin/LMWH
abruptio
IUFD
one who is on Heparin/LMWH
Why is the SVR decreased in 3rd trimester pregnant women?
Because of the increase in progesterone, prostacylclin and development of placental unit
The type of hemorrhage with the highest likelihood of DIC
a) Placenta accreta
b) Placenta abruption
c) Placenta previa
Placenta abruption
Risk factors for placenta accreta
a) known placenta previa
b) 4 prior C-sections
c) large neonate
d) polyhydramnios
known placenta previa
4 prior C-sections
With placenta abruption when would it be safe to deliver vaginally (the preferred method)?
Reassuring FHT
No ongoing blood loss
No hypovolemia
No coagulopathy
Placenta Previa
a) must do a C-section
b) vaginal delivery preferred
c) delivery stops bleeding
d) is associated with DIC
must do a C-section

delivery stops bleeding
T/F long term pitocin down regulates pitocin receptors
TRUE, May lead to uterine atony!
Pregnant woman with asthma & HTN has uterine atony what is the appropriate medication for the atony
a) methergine (ergonovine)
b) prostglandin F2 alpha
c) pitocin
pitocin
Pregnant woman with HTN has uterine atony what is the appropriate medication for the atony
a) methergine (ergonovine)
b) prostglandin F2 alpha
c) pitocin
Pitocin or maybe prostglandin F2 alpha if used with caution
Pregnant woman with asthma has uterine atony what is the appropriate medication for the atony
a) methergine (ergonovine)
b) prostglandin F2 alpha
c) pitocin
Pitocin or methergine
Pregnancy induced HTN
a) >20wks gestation
b) prior to 20 weeks gestation
>20wks gestation PREECLAMPSIA
Chronic HTN
a) >20wks gestation
b) prior to 20 weeks gestation
prior to 20 weeks gestation
One theory for preeclampsia is
a) increased thromboxane relative to prostacycline
b) decreased thromboxane relative to prostacycline
increased thromboxane relative to prostacycline (vasoconstriction leading to dying tissue and the cascade which leads to decreased O2, decreased uteroplacental perfusion
Preeclampsia
a) proteinurea
b) edema
c) HTN
d) seizures
proteinurea
edema
HTN SBP>140 DBP>90
Severe Preeclampsia
a) SBP>140, DBP>90
b) SBP>160, DBP>110
c) protein > 5
d) oliguria
e) HELLP syndrome
SBP>160, DBP>110
protein > 5
oliguria
HELLP syndrome
ONLY NEED ONE OF THESE TO BE CONSIDERED SEVERE
Definitive therapy for preeclampsia is?
DELIVERY!!!!!
Hydralazine
a) treatment for PIH
b) increases CI, decreases SVR
c) increases uteroplacental perfusion
d) neonatal HOTN
a) treatment for PIH
b) increases CI, decreases SVR
c) increases uteroplacental perfusion
d) neonatal HOTN (no severe adverse effect)
The top 2 reasons for morbidity & mortality r/t HTN in a pregnant woman?
a) CVA
b) hemorrhage
c) MI
d) seizures
#1 CVA
#2 MI
Which of the following cross the placenta
a) glucose
b) insulin
c) glucagon
d) oral hypoglycemics
ONLY glucose which is why neonates of diabetic moms have a high risk of hyperglycemia initially then a PROFOUND DROP 2 HOURS LATER!!
In a diabetic pregnant woman
a) increased risk of hypoglycemia after delivery
b) increased risk of hyperglycemia after delivery
c) insulin resistance is developed
increased risk of hypoglycemia after delivery (AFTER DELIVERY THERE IS NO MORE PLACENTA INSULINASE)
insulin resistance is developed
Gestational Trophoblasitc Neoplasms
a) mimic pregnancy
b) produce high levels of Hcg
c) hyperemesis
d) hyperthyroid
e) produce preeclampsia
mimic pregnancy
produce high levels of Hcg
hyperemesis
hyperthyroid
produce preeclampsia
Of the three types of Embolism which one is the ONLY one associated with DIC
a) Air
b) Thrombotic
c) Amniotic Fluid
Amniotic Fluid
Signs & symptoms of Amniotic Fluid Embolism
a) HOTN
b) SOB
c) pain
d) pulmonary edema
HOTN
SOB
pain
pulmonary edema
T/F Ketamine would be used in a pregnant woman with HOTN and severe hemorrhage
TRUE, remember doses >2mg decrease placental blood flow
Preeclampsia
a) increased risk premature birth
b) risk of CVA
c) alterations in lytes
d) no alterations in lytes
e) no decreases in Hgb, O2
increased risk premature birth
risk of CVA
no alterations in lytes
no decreases in Hgb, O2
Increases of progesterone during pregnancy
a) prolong NDMR
b) prolong Sux
c) decrease MAC requirement
d) shorten NDMR effects
prolong NDMR
prolong Sux
decrease MAC requirement
Magnesium sulfate
a) treatment for ecclampsia
b) treatment for preeclampsia
c) decreases MAC requirement
d) increases MAC requirment
treatment for preeclampsia
decreases MAC requirement
Peripartum cardiomyopathy
a) peak incidence right after delivery
b) peak incidence 2 mths after delivery
c) increases O2 demand
d) peak incidence 48 hrs after delivery
peak incidence 2 mths after delivery

increases O2 demand
In pt with Marfan syndrome
a) avoid HOTN
b) avoid HTN
avoid HTN
Neonatal resuscitation
a) atropine 0.03mg/kg
b) epinephrine 0.1ml/kg of 1:10,000 (0.01%)
c) bicarb 1-2mEq of a 0.5mEq/ml solution
d) narcan 0.1mg/kg
atropine 0.03mg/kg
b) epinephrine 0.1ml/kg of 1:10,000 (0.01%)
c) bicarb 1-2mEq of a 0.5mEq/ml solution (if prolonged resuscitation)
d) narcan 0.1mg/kg (if within 4 hours of narcotic to mom and not a drug addict)
Fetal mortality for breech delivery
Vaginal > C-section?
Yes!!
MgSO4, Ntg, Hydralazine all
increase/decrease uterine blood flow
INCREASE
In the years from 1999-2000 the top 4 reasons pregnancy related Mortality in North Carolina were
a) Peripartum cardiomyopathy
b) Obstetric hemorrhage
c) Pregnancy induced HTN
d) Infection
e) Anesthesia complications
#1 Peripartum cardiomyopathy

#2 Obstetric hemorrhage

#3 Pregnancy induced HTN

#4 Infection
Treatment of Peripartum Cardiomyopathy
a) preload & afterload reduction
b) inotropic agents
c) fluid restriction
d) all of the above
reload & afterload reduction
inotropic agents
fluid restriction
Of the following drugs which one are OK for use in the peripartum stage
a) amlodipine
b) hydralazine
c) digoxin
d) beta blockers
e) ACEI's
amlodipine
hydralazine
beta blockers (caution as can cause IUGR)

NO ACEI's or DIGOXIN!!!
ACEI's can cause what in fetus?
Renal failure
Why should anticoagulation therapy be considered in pregnant women with cardiomyopathy?
a) hypercoagulable state
b) depressed ejection fraction
c) stasis and turbulent flow in the dilated heart
d) all of the above
hypercoagulable state
depressed ejection fraction
stasis and turbulent flow in the dilated heart
If medical management of peripartum cardiomyopathy is successful
a) early delivery is not required
b) Vaginal delivery should be avoided
c) Vaginal delivery does not have to be avoided
d) passive 2nd stage delivery should be used
early delivery is not required

Vaginal delivery does not have to be avoided
T/F Passive 2nd stage or assisted delivery is used to prevent complications from the valsalva maneuver when pushing.
TRUE
Why are vaginal deliveries preferable to C-Sections in peripartum cardiomyopathy?
Reduced risk of endometritis, PE, and post-op complications
T/F Combined epidural is preferred over Epidural anesthesia in peripartum cardiomyopathy
TRUE because of lower failure rates associated with CSE and decreased PDPH
Which pts with peripartum cardiomyopathy have a lower morbidity rate
a) higher EF
b) lower EF
c) smaller LVED diameters
d) larger LVED diameters
higher EF
smaller LVED diameters (so blood is not just floating around in a big sack)
Risk factors for placental abruption
a) cocaine
b) HTN
c) previous abruption
d) Heavy ETOH use
cocaine
HTN
Heavy ETOH use
T/F 90% of abruptions are mild or moderate & without fetal distress, maternal hypotension or coagulopathy
TRUE
What labs would you want to be sure to draw on a pt with placenta abruption?
Coags, CBC, T&C

THESE PTS ARE PRONE TO BLEEDING!!
Is there a problem with uterine atony in placenta abruption?
Yes, possibly because blood may infiltrate the myometrium and inhibit adequate uterine contraction
T/F all bleeding in 3rd trimester should be considered placenta previa
TRUE
Risk factors for placenta previa
a) multiparity
b) previous C-Section
c) prior previa
d) scar tissue
multiparity
previous C-Section
prior previa
scar tissue
Your patient comes in with painless vaginal bleeding in the 3rd trimester you suspect?
placenta previa

DIAGNOSED WITH U/S
What is definitive treatment for placenta previa?
DELIVERY WITH A C-SECTION!!!!
T/F there is an increased risk for placenta acreta, increta, percreta with placenta previa
TRUE
With uterine rupture one risk factor is previous C-Section which type of incision is more likely to lead to rupture?
Vertical or CLASSIC INCISION
Symptoms of uterine rupture
a) vaginal bleeding
b) severe abdominal pain/shoulder pain
c) disapperance of fetal heart tones
d) HOTN
vaginal bleeding
severe abdominal pain/shoulder pain
disapperance of fetal heart tones
HOTN
T/F retained placenta is the most common cause of serious blood loss
TRUE!!!! if the uterus does not empty completely it will NOT contract!

NEED UTERINE RELAX >1 MAC
In the absence of the Decidua basalis in the uterus what can this lead to?
a) placenta abruptio
b) placenta accreta
c) ruptured uterus
d) uterine atony
placenta accreta placenta implants directly onto or into the myometrium Separation of placenta after delivery is incomplete = HIGH BLOOD LOSS
T/F HELLP syndrome increases risk for DIC
TRUE
Placental ischemia in preeclampsia could be due to?
increase in placental thromboxane which leads to vasoconstriction, platelet aggregation and uteroplacental hypoperfusion
CNS symptoms of preeclampsia
a) irritability
b) HA
c) vision changes
d) hyperreflexia
irritability
HA
vision changes
hyperreflexia
Hepatic signs of preeclampsia
a) elevated SGOT
b) elevated LDH
c) both of the above
elevated SGOT
elevated LDH
With preeclampsia
a) GFR decreases
b) GFR increases
c) BUN increases
d) BUN decreases
GFR decreases

BUN increases
With preeclampsia
a) decreased platelets
b) impaired platelet function
c) DIC
decreased platelets
impaired platelet function
DIC
In the preeclamptic pt
a) SVR is elevated
b) SVR is decreased
c) CI is increased
d) CI is decreased
SVR is elevated

CI is decreased
Preeclamptic pts will be
a) hypovolemic
b) hypervolemic
Hypovolemic
Definitive therapy for preeclampsia is?
DELIVERY careful volume repletion (restoring R & L side filling pressures which normalizes CI, HR, SVR, and improves tissue and fetal perfusion)
T/F the use of muscle relaxants in pt with preeclampsia on MgSO4 should be avoided
FALSE, just carefully dosed!
Placental transfer & fetal uptake of MgSO4
a) fetal hypermagnesemia
b) respiratory depression
c) low apgar scores
d) fetal hypotonia
fetal hypermagnesemia
respiratory depression
low apgar scores
fetal hypotonia
Labetalol and propranolol may cause what in the fetus?
IUGR
Esmolol
a) decrease uterine blood flow
b) increase uterine blood flow
c) fetal hypoxia
d) late decelerations
e) bradycardia
f) fetal acidosis
decrease uterine blood flow
fetal hypoxia
late decelerations
bradycardia
fetal acidosis
Calcium channel blockers
a) possible teratogenic effects
b) may cause uterine atony
c) may cause ongoing blood loss
possible teratogenic effects
may cause uterine atony (lack of Ca for contractions)
may cause ongoing blood loss (lack of contractions)
T/F Nitroprusside and Nitroglycerine may be used during intubation for pregnant woman in HTN crisis
TRUE risk of fetal cyanide toxicity and fetal wastage with large doses
Anesthestic management of preeclamptic woman
a) vaginal delivery/C-Section
b) check plt level q 6h
c) regional anesthesia
d) no regional anesthesia
vaginal delivery/C-Section
check plt level q 6h
regional anesthesia
T/F regional anesthesia may or may not result in HOTN, but will improve urinary output
TRUE
When would a general anesthetic be required in a pt with preeclampsia?
Emergency, coagulopathy

REMEMBER INTUBATION MAY BE DIFFICULT DUE TO EDEMA consider smaller ETT
Why is a premature infant at an increased risk of intracranial hemorrhage?
Due to soft cranial bones and fragile dura
T/F preemies have decreased protein binding, decreased metabolism and excretion, and immature respiratory centers
TRUE
Gestational Trophoblastic neoplasms
a) high cardiac output from thyrotoxicosis
b) pulmonary congestion from severe anemia
c) PIH
d) Aspiration pneumonitis
high cardiac output from thyrotoxicosis
pulmonary congestion from severe anemia
PIH
Aspiration pneumonitis
What is the most common acquired cardiac (valve) problem ?
Mitral Stenosis
What is the number one congenital malformation?
Atrial-septal defect ASD
Fatigue, dyspnea, pulsation of neck veins, systolic murmurs occasional palpitations are
a) normal observations in a pregnant woman
b) abnormal observations in a pregnant woman
NORMAL
Syncope, nocturnal dyspnea, HR >120, distention of neck veins, SOB at rest, diastolic murmur
a) normal observations in a pregnant woman
b) abnormal observations in a pregnant woman
ABNORMAL, A PREGNANT WOMAN DOES NOT FAINT NORMALLY!!!
High cardiac risk factors during pregnancy
a) Pulmonary HTN
b) left ventricular dysfunction
c) Marfan syndrome
d) cardiomyopathy (EF <40%)
e) coartation of the aorta
Pulmonary HTN

Marfan syndrome

cardiomyopathy (EF <40%)

coartation of the aorta
With cardiac disease in pregnancy preterm delivery/respiratory distress syndrome is the most common adverse neonatal outcome
preterm delivery
Treatment for ASD in pregnancy includes
a) optimize preload
b) oxygen during labor
c) avoid HOTN
d) avoid tachycardia
e) labor in lateral recumbent postion
optimize preload
oxygen during labor
avoid HOTN
avoid tachycardia (may increase left to right shunting!)
labor in lateral recumbent position
With Eisenmenger syndrome it is important to avoid conditions that increase __________
PVR
metabolic acidosis
hypoxemia
hypercapnia
vasoconstrictors
A woman with previous history of MI is advised to wait how long before becoming pregnant?
at least 1 year
With a woman who has suffered an MI during pregnancy how long is delivery attempted to be delayed?
2-3 weeks so that will be able to handle the fluid shifts that will occur with delivery
Mitral regurg/Mitral stenosis which one is placing an epidural OK in?
Mitral Regurg this patient likes preload and tachycardia!

Mitral Stenosis can't handle HOTN
When reversing muscle relaxants why is it important to give them slowly?
because acute increases in AcH can induce uterine contractions