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106 Cards in this Set
- Front
- Back
16. The skeleton does not
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store red blood cells.
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17. Osseous tissue is a(an) ____________ tissue.
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connective
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18. These are all tissues that make up a long bone except
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transitional epithelium.
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19. The four groups of bones include all the following except
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rounded bones.
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23. The expanded head at each end of a long bone is called
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an epiphysies.
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24. A bone is covered externally with a sheath called ______________, whereas the internal surface is lined with _____________.
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periosteum; endosteum
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25. _____________ are bone-forming cells.
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Osteoblasts
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26. When ____________ become enclosed in lacunae, they become cells called _____________.
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osteocytes; osteoclasts
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28. Which of these is an inorganic component of the bone matrix?
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Hydroxyapatite
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29. Spicules and trabeculae are found in
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spongy bone.
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31. ____________ provide(s) hardness to bones, whereas ____________ provide(s) some degree of flexibility.
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Hydroxyapatite and other minerals; proteins
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32. ___________ have a ruffled border with many deep infoldings of the plasma membrane, whereas ____________ have long, thin, fingerlike cytoplasmic processes.
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Osteoclasts; osteocytes
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34. Which one of the following bone cells would have the greatest number of lysosomes?
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osteoclasts
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35. _______________ are common in compact bone but rarely seen in spongy bone.
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Osteocytes
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36. Intramembranous ossification produces the
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flat bones of the skull.
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37. Endochondral ossification is a precursor made of _____________ is replaced by bone.
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hyaline cartilage.
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38. The _____________ is a marginal zone of the epiphyseal plate where, in children and adolescents, bone can be seen replacing the hyaline cartilage.
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metaphysis
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40. Chondrocytes multiply in this zone of the metaphysis.
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zone of cell proliferation
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41. Mature bones are remodeled throughout life by employing
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appositional growth.
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42. Bone elongation is a result of
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cartilage growth.
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43. Wolff's law of bone explains the effect of
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mechanical stress on bone remodeling.
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45. _____________ is the process of dissolving bone and returning its minerals to the bloodstream.
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Resorption
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47. Phosphate is necessary for all of the following except
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amino acids.
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48. Calcium plays an essential role in all of the following except
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DNA synthesis.
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49. Parathyroid hormone (PTH) does not
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lower blood calcium.
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50. ____________ is synthesized by the combined action of the skin, kidneys, and liver, and is important to the deposition of bone.
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Calcitriol
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52. ____________ does not put women at risk of hypocalcemia.
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Removal of the thyroid gland
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53. Blood Ca2+ deficiency stimulates __________ secretion, which leads to _____________.
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parathyroid hormone; increased osteoclast activity
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54. Hypocalcemia can cause
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spasms.
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55. Arteriosclerosis is one example of ectopic ossification, which means
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abnormal calcification of a tissue.
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56. If a thyroid tumor secreted an excessive amount of calcitonin, we would expect
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an elevated level of osteoblast activity.
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57. A soft callus forms during
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the healing of a fracture.
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58. Osteoporosis is most common in elderly women because of the lack of ___________, which would otherwise inhibit ____________.
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estrogen; osteoclast activity
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59. A fracture in which the bone is broken into three or more pieces is called a __________ fracture.
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comminuted
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60. The result of calcium and phosphate levels in blood too low for normal deposition is a softness of the bones called ___________ in children and ___________ in adults.
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rickets; osteomalacia
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61. Bone protrudes through skin in a fracture called
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open.
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62. A pathologic fracture
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is a break in a bone weakened by some other disease.
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63. Which of the following is the correct sequence of events in the healing of a bone fracture?
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hematoma formation soft callus formation hard callus formation bone remodeling
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64. Patches of fibrocartilage formed in the healing of a fracture are called ________, whereas the bony collar formed around the fracture is called _________.
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soft callus; hard callus
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65. ____________ affects more people than any other bone disease.
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Osteoporosis
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Functions of the skeletal system include:
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acid-base balance blood cell production detoxification regulation of certain electrolytes
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Which of the following is a mature bone cell that appears to be responsible for the overall supervision of bone maintenance?
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osteogcytes
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This type of fracture is defined solely by the fact that the skin is not broken.
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closed fracture
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The basic structural unit of compact bone is termed:
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osteon
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The hormone calcitonin is an important hormone in:
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children
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In an elderly person, most of the bone marrow is a
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gelatinous material
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The humerus and femur develop by the process of :
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endochondral ossification
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What are the functions of the skeletal system?
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muscle attachment production of blood cells mineral reservoir
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the shaft of a long bone, such as the femur, is known as the:
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diaphysis
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Osteocytes are mature:
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osteoblasts
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About 85% of the inorganic matter of bone is a crystallized calcium phosphate salt known as:
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hydroxyapatite
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Intramembranous ossification in the fetus produces the flat bones of the skull, when _____________________ transforms directly into bone.
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mesenchyme
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In which of the histological zones of a developing long bone would you find osteoclasts?
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zone of calcified cartilage
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Ossification in abnormal locations is called:
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ectopic ossification
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Hypocalcemia causes which of the following?
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muscle tremors or spasms
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Which of the following hormones involved with calcium homeostasis is secreted by the thyroid glands?
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calcitonin
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Parathyroid hormone is secreted when the blood calcium concentration:
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drops too low
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Which of the following is the adult form of rickets in which the bones become softened and deformed?
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osteomalacia
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In which of the following types of fractures is a bone broken into three or more pieces?
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comminuted
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Estrogen replacement therapy cannot reverse osteoporosis, but:
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but it can slow its progress.
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The sheath of fibrous connective tissue covering the outside of a bone is called the:
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periosteum
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These large multinucleate cells found in bones secrete enzymes to reabsorb matrix:
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osteoclasts
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These are little cavities occupied by osteocytes in living bones:
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lacunae
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This bone develops by intramembranous ossification:
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cranium
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The first step in making a long bone such as the femur is:
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hyaline cartilage model formed
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In this dominant genetic condition, the chondrocytes fail to multiply:
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achondroplasia
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Parathyroid hormone raises blood calcium concentration by all of the following:
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stimulating the dissolving of bone matrix increases number of ostenoclasts reduces calcium excretion inhibits osteoblasts
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All of these organs or organ systems participate in vitamin D production or activation:
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parathyroid gland skin liver kidney
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This condition results from little exercise and lack of estrogen after menopause:
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osteomalacia
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This type of fracture is common in young adults active in sports:
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Pott
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Which cells have a ruffled border and secret hydrochloric acid?
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osteoclasts
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the medullary cavity of an adult bone may contain
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myeloid tissue
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the spurt of growth in puberty results from cell proliferation and hypertrophy in
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the epiphyseal plate
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osteoclasts are most closely related, by common descent, to:
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monocytes
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the walls between cartilage lacunae break down in the zone of:
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bone deposition
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Which of these is an effect of PTH?
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reduction of calcium excretion
increased intestinal calcium absorption increaded numbert of osteoclasts increased calcitriol synthesis |
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A child jumps to the ground from the top of the playground "jungle gym." His leg bones do not shatter mainly because they contain:
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collagen fibers
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One long bone meets another at its:
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epiphysis
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Calcitriol is made from
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7-dehydrocholesterol
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One sign of osteoporosis is:
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Colles fracture
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Calcium phosphate crystallizes in bone as a mineral called:
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hydroxyapatite
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Osteocytes contact each other through channels called ______________ in the bone matrix.
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canaliculi
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A bone increases in diameter only by ____________ growth, the addition of new surface osteons.
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appositional
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Seed crystals of hydroxyapatite form only when the levels of calcium and phosphate int the tissue fluid exceed the ___________.
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solubility product
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A calcium deficiency called _______________________ an cause death by suffocation.
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hypocalcemia
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________________________ are cells that secrete collagen and stimulate calcium phosphate deposition.
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osteoblasts
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The most active form of vitamin D. produces mainly by the kidneys, is ____________________
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calcitriol [1,25(OH)2D]
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The most common bone disease is ________________
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osteoporosis
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The transitional region between epiphyseal cartilage and the primary marrow cavity of a young bone is called _________________
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metaphysis
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A pregnant, poorly nourished woman may suffer a softening of the bones called __________
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osteomalacia
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Spongy bone is always covered by:
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compact bone
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Most bones develop from:
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hyaline cartilage
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Osteocytes develop from:
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osteoblasts
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Blood vessels travel through the central canals of
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compact bone
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Parathyroid hormone promotes bone resorption and ___________________________________
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raises blood calcium concentation
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The growth zone of the long bones of adolescents is the is the:
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epiphyseal plate
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The protein of the bone matrix is called:
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collagen
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______________________ is the major mineral of bone
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hydroxyapatite
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bones elongate at the _____________
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epiphyseal plate
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The major effect of vitamin D is:
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bone resorption
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Vitamin D promotes:
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deposition
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The skeleton:
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store calcium and phosphate ions.
provide support for most muscles. protect the brain. protect the spinal cord |
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What are 4 tissues that make up a long bone
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osseous tissue.
nervous tissue adipose tissue. cartilage. |
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The four groups of bones are:
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long bones.
short bones. irregular bones. flat bones |
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Calcium plays an essential role in all of the following:
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muscle contraction.
exocytosis. blood clotting. communication among neurons |
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Phosphate is necessary for all of the following except
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ATP.
DNA. phospholipids. RNA. |