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106 Cards in this Set

  • Front
  • Back
16. The skeleton does not
store red blood cells.
17. Osseous tissue is a(an) ____________ tissue.
connective
18. These are all tissues that make up a long bone except
transitional epithelium.
19. The four groups of bones include all the following except
rounded bones.
23. The expanded head at each end of a long bone is called
an epiphysies.
24. A bone is covered externally with a sheath called ______________, whereas the internal surface is lined with _____________.
periosteum; endosteum
25. _____________ are bone-forming cells.
Osteoblasts
26. When ____________ become enclosed in lacunae, they become cells called _____________.
osteocytes; osteoclasts
28. Which of these is an inorganic component of the bone matrix?
Hydroxyapatite
29. Spicules and trabeculae are found in
spongy bone.
31. ____________ provide(s) hardness to bones, whereas ____________ provide(s) some degree of flexibility.
Hydroxyapatite and other minerals; proteins
32. ___________ have a ruffled border with many deep infoldings of the plasma membrane, whereas ____________ have long, thin, fingerlike cytoplasmic processes.
Osteoclasts; osteocytes
34. Which one of the following bone cells would have the greatest number of lysosomes?
osteoclasts
35. _______________ are common in compact bone but rarely seen in spongy bone.
Osteocytes
36. Intramembranous ossification produces the
flat bones of the skull.
37. Endochondral ossification is a precursor made of _____________ is replaced by bone.
hyaline cartilage.
38. The _____________ is a marginal zone of the epiphyseal plate where, in children and adolescents, bone can be seen replacing the hyaline cartilage.
metaphysis
40. Chondrocytes multiply in this zone of the metaphysis.
zone of cell proliferation
41. Mature bones are remodeled throughout life by employing
appositional growth.
42. Bone elongation is a result of
cartilage growth.
43. Wolff's law of bone explains the effect of
mechanical stress on bone remodeling.
45. _____________ is the process of dissolving bone and returning its minerals to the bloodstream.
Resorption
47. Phosphate is necessary for all of the following except
amino acids.
48. Calcium plays an essential role in all of the following except
DNA synthesis.
49. Parathyroid hormone (PTH) does not
lower blood calcium.
50. ____________ is synthesized by the combined action of the skin, kidneys, and liver, and is important to the deposition of bone.
Calcitriol
52. ____________ does not put women at risk of hypocalcemia.
Removal of the thyroid gland
53. Blood Ca2+ deficiency stimulates __________ secretion, which leads to _____________.
parathyroid hormone; increased osteoclast activity
54. Hypocalcemia can cause
spasms.
55. Arteriosclerosis is one example of ectopic ossification, which means
abnormal calcification of a tissue.
56. If a thyroid tumor secreted an excessive amount of calcitonin, we would expect
an elevated level of osteoblast activity.
57. A soft callus forms during
the healing of a fracture.
58. Osteoporosis is most common in elderly women because of the lack of ___________, which would otherwise inhibit ____________.
estrogen; osteoclast activity
59. A fracture in which the bone is broken into three or more pieces is called a __________ fracture.
comminuted
60. The result of calcium and phosphate levels in blood too low for normal deposition is a softness of the bones called ___________ in children and ___________ in adults.
rickets; osteomalacia
61. Bone protrudes through skin in a fracture called
open.
62. A pathologic fracture
is a break in a bone weakened by some other disease.
63. Which of the following is the correct sequence of events in the healing of a bone fracture?
hematoma formation  soft callus formation  hard callus formation  bone remodeling
64. Patches of fibrocartilage formed in the healing of a fracture are called ________, whereas the bony collar formed around the fracture is called _________.
soft callus; hard callus
65. ____________ affects more people than any other bone disease.
Osteoporosis
Functions of the skeletal system include:
acid-base balance blood cell production detoxification regulation of certain electrolytes
Which of the following is a mature bone cell that appears to be responsible for the overall supervision of bone maintenance?
osteogcytes
This type of fracture is defined solely by the fact that the skin is not broken.
closed fracture
The basic structural unit of compact bone is termed:
osteon
The hormone calcitonin is an important hormone in:
children
In an elderly person, most of the bone marrow is a
gelatinous material
The humerus and femur develop by the process of :
endochondral ossification
What are the functions of the skeletal system?
muscle attachment production of blood cells mineral reservoir
the shaft of a long bone, such as the femur, is known as the:
diaphysis
Osteocytes are mature:
osteoblasts
About 85% of the inorganic matter of bone is a crystallized calcium phosphate salt known as:
hydroxyapatite
Intramembranous ossification in the fetus produces the flat bones of the skull, when _____________________ transforms directly into bone.
mesenchyme
In which of the histological zones of a developing long bone would you find osteoclasts?
zone of calcified cartilage
Ossification in abnormal locations is called:
ectopic ossification
Hypocalcemia causes which of the following?
muscle tremors or spasms
Which of the following hormones involved with calcium homeostasis is secreted by the thyroid glands?
calcitonin
Parathyroid hormone is secreted when the blood calcium concentration:
drops too low
Which of the following is the adult form of rickets in which the bones become softened and deformed?
osteomalacia
In which of the following types of fractures is a bone broken into three or more pieces?
comminuted
Estrogen replacement therapy cannot reverse osteoporosis, but:
but it can slow its progress.
The sheath of fibrous connective tissue covering the outside of a bone is called the:
periosteum
These large multinucleate cells found in bones secrete enzymes to reabsorb matrix:
osteoclasts
These are little cavities occupied by osteocytes in living bones:
lacunae
This bone develops by intramembranous ossification:
cranium
The first step in making a long bone such as the femur is:
hyaline cartilage model formed
In this dominant genetic condition, the chondrocytes fail to multiply:
achondroplasia
Parathyroid hormone raises blood calcium concentration by all of the following:
stimulating the dissolving of bone matrix increases number of ostenoclasts reduces calcium excretion inhibits osteoblasts
All of these organs or organ systems participate in vitamin D production or activation:
parathyroid gland skin liver kidney
This condition results from little exercise and lack of estrogen after menopause:
osteomalacia
This type of fracture is common in young adults active in sports:
Pott
Which cells have a ruffled border and secret hydrochloric acid?
osteoclasts
the medullary cavity of an adult bone may contain
myeloid tissue
the spurt of growth in puberty results from cell proliferation and hypertrophy in
the epiphyseal plate
osteoclasts are most closely related, by common descent, to:
monocytes
the walls between cartilage lacunae break down in the zone of:
bone deposition
Which of these is an effect of PTH?
reduction of calcium excretion
increased intestinal calcium absorption
increaded numbert of osteoclasts
increased calcitriol synthesis
A child jumps to the ground from the top of the playground "jungle gym." His leg bones do not shatter mainly because they contain:
collagen fibers
One long bone meets another at its:
epiphysis
Calcitriol is made from
7-dehydrocholesterol
One sign of osteoporosis is:
Colles fracture
Calcium phosphate crystallizes in bone as a mineral called:
hydroxyapatite
Osteocytes contact each other through channels called ______________ in the bone matrix.
canaliculi
A bone increases in diameter only by ____________ growth, the addition of new surface osteons.
appositional
Seed crystals of hydroxyapatite form only when the levels of calcium and phosphate int the tissue fluid exceed the ___________.
solubility product
A calcium deficiency called _______________________ an cause death by suffocation.
hypocalcemia
________________________ are cells that secrete collagen and stimulate calcium phosphate deposition.
osteoblasts
The most active form of vitamin D. produces mainly by the kidneys, is ____________________
calcitriol [1,25(OH)2D]
The most common bone disease is ________________
osteoporosis
The transitional region between epiphyseal cartilage and the primary marrow cavity of a young bone is called _________________
metaphysis
A pregnant, poorly nourished woman may suffer a softening of the bones called __________
osteomalacia
Spongy bone is always covered by:
compact bone
Most bones develop from:
hyaline cartilage
Osteocytes develop from:
osteoblasts
Blood vessels travel through the central canals of
compact bone
Parathyroid hormone promotes bone resorption and ___________________________________
raises blood calcium concentation
The growth zone of the long bones of adolescents is the is the:
epiphyseal plate
The protein of the bone matrix is called:
collagen
______________________ is the major mineral of bone
hydroxyapatite
bones elongate at the _____________
epiphyseal plate
The major effect of vitamin D is:
bone resorption
Vitamin D promotes:
deposition
The skeleton:
store calcium and phosphate ions.
provide support for most muscles.
protect the brain.
protect the spinal cord
What are 4 tissues that make up a long bone
osseous tissue.
nervous tissue
adipose tissue.
cartilage.
The four groups of bones are:
long bones.
short bones.
irregular bones.
flat bones
Calcium plays an essential role in all of the following:
muscle contraction.
exocytosis.
blood clotting.
communication among neurons
Phosphate is necessary for all of the following except
ATP.
DNA.
phospholipids.
RNA.