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52 Cards in this Set

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Novolin R
Humulin R
only insulin that can be given IV
Rapid-Analog
Insulin
Humalog (lispro)
Novolog (aspart)
Aprida (glulisine
Short-acting
Insulin
Novolin R
Humulin R
Intermediate Acting
Insulin
Humulin N (NPH)
Novolin N (NPH
Maintenance
Combinations
Insulin
Novolin 70/30
Humulin 70/30, 50/50
Humalog 75/25, 50/50
Novolog 70/30
Incretin Mimetics
Byetta
Symlin
Symlin
Mainly Type 1, some type 2. Prevents post prandial rise plasma glucose. Slows gastric emptying.
SQ. Do not mix. Side effects hypoglycemia and nausea (25%)
Byetta
Type 2. Slows gastric emptying. Improves insulin secretion with meal. Adjunct with metformin, sulfinyurea or combination when need to achieve glycemic control. Give 1 hour before morning and evening meal. Recently noted it may cause pancreatitis but actual studies indicate it hasn’t been established that it will cause so it’s still being prescribed.
SQ. Do not mix. Side effects hypoglycemia and nausea (25%)
Inhaled Insulin
Exubera: Off the market November 2007.
Rapid acting. (meal control) Still need another type. FDA approved for Type 1 & 2
Not in Ohio yet.
Dosed in mg not units. Can’t use of smoked 6 months. Causes dry mouth, cough.
Sulfonyureas:
Most commonly used oral agents in US. Stimulates pancreas to secrete insulin. Only used in Type II. Why? Second generation drugs: Glyburide (Diabeta, micronase), Glucotrol, Amaryl.
Shorter acting. Take 1/2 hour before eating.
Meglitinides:
Prandin. Lower the blood glucose by stimulating insulin release from the pancreatic beta cells. Indicated for Type II DM. Has fast action and short duration. Taken immediately before meal.
Biguanides:
Metaformin (Glucophage): decreases hepatic glucose production; decreases intestinal glucose absorption; increases tissue response to insulin. Doesn’t stimulate insulin secretion. Side effects: diarrhea; caution with Renal Failure-hold 48hrs before any dye test.
Thiazolidinediones:
Avandia and Actos. Indicated for Type II, receiving Insulin with poor control. Can also be used for Type II DM. They act by decreasing insulin resistance and enhancing insulin action at the receptor sites.
Alpha Glucosidase Inhibitor
(with first bite of food). Acarbose (Precos). It works by altering how fast carbohydrates are absorbed by the body. Works in digestive tract to delay absorption. Side effect: diarrhea. Or Glyset.
D-Phenylalanine Derivitives
Starlix. Rapid action to lower blood glucose. Lower BS by stimulating release insulin from pancreatic beta cells. Type II. Fast action short duration. Take immediately before meal.
Januvia (Sitagliptin)
works 24 hours/day. Increases insulin made in pancreas and decreases sugar production by liver to lower BS. No increase risk hypoglycemia. Can be given with metformin, avandia or actos.
Mixing insulin
clear before cloudy
Rapid-analog insulin
Humalog (lispro)
Novolog (aspart)
Aprida (glulisine)
Onset Peak Duration
15 min 1 hr 1-3 hrs
Short-acting insulin
Novolin R
Humulin R
Onset Peak Duration
3-4 6-12 (8) 16-20
Long Acting Basal
Lantus (Glargine)
Levemir (Glargine)
Onset Peak Duration
2-4 hr 24 hrs
Continuous no peak
Sulfonyureas
Glyburide (Diabeta, Micronase, Glynase) & Glipizide (Glucotrol) , Glimepiride (Amaryl)
Meglitinides:
Repaglinide (Prandin)
Biguanides
Metaformin (Glucophage)
Thiazolidinediones
Avandia (Rosiglitazone), Actos (Pioglitazone)
Alpha Glucosidase Inhibitor (with first bite of food)
Precos (Acarbose), Migitol (Glyset)
D-Phenylalanine Derivatives
Nateglinide (Starlix)
Hypoglycemia
also called insulin reaction, insulin shock, and low blood sugar.
BS levels of 40 to 60 mg/d
ingestion of 15 grams simple sugar
3 commercially prepared glucose tablets
4 ounces fruit juice or regular pop
5 life savers or hard candy
3 tsp sugar or honey
Betty Crocker frosting gel (small tube)
Do not add sugar to juice.
BS of 20 to 40 mg
In the hospital, 50% dextrose solution by IV push is the treatment of choice
15-15 rule
15 gms CHO and recheck BS in 15 min and repeat if not back to normal
Hypoglycemia s/s
Skin cool, clammy
No s/s dehydration
Diaphoresis
Nervous, shaky
Blurred vision
Hyperglycemia s/s
Skin warm, dry
S/S dehydration
Skin dry
Drowsiness
Thirst
Hypoglycemia 20-40
In the hospital, 50% dextrose solution by IV push is the treatment of choice for the client in seizure or the unconscious person with low BS. Severe reaction.
Also could have given glucagon as stated earlier if no IV access.
DIET THERAPY for diabetes
Low simple sugar
CARBOHYDRATE COUNTING
1 SERVING =15 GMS
Protein 20%; Fats <30%; rest complex carbohydrates (50%)
Increased fiber
Low Simple sugar diet for diabetes
is often seen as an ordered diet in the hosp. is avoiding simple sugars Basically, this is Carbohydrate Counting. .
Carbohydrate Counting
It is recommended to consume more complex carbohydrates, high in fiber. One carbohydrate serving equals 15 grams. The client is allowed 3-4 servings per meal depending on weight and sex.
Fruits, vegetables, whole grains are the preferred carbohydrates.
Fiber effects on glucose levels
increase fiber intake which decreases insulin requirements and cholesterol. Make sure to increase fluids with increased fiber. 20-40 grams of fiber.
Alcohol effects on glucose levels
Is not prohibited but decreases normal process that produces glucose in body. It lowers BS and also potentiates meds. Recommendation no more than 2 drinks per day = 12 oz. beer/5 oz. wine/1.5 oz. liquor. Light beer recommended.
Exercise role in dibetes management
Exercise plays an important part of the management regimen. Regular exercise improves physical fitness, which may help to reduce the incidence of heart disease, stroke, and hypertension. Daily walk, light aerobics, or swimming.
Exercise effects on diabetes
hypoglycemia effect
The Rule is to eat meal 1-2 hrs. before exercising. Take CHO if exercising > 30 minutes and check blood sugar as needed.
Use proper footwear when exercising. Avoid exercising in extreme heart or cold. Inspect feet after exercising.
Foot care for diabetic
Check feet daily.
Wash with mild soap daily, dry well, especially between toes.
Do not soak.
Don’t use heating pad.
Apply cream; not between toes.
Do not self-treat corn, calluses.
Cut toenails across after bathing. See podiatrist if too thick to cut.
Measures to increase circulation: do not cross legs.
How does the physician assess compliance of diabetes management?
HgbA1C.
HgbA1C.
This tests the average blood glucose over a 2-3 month period. When blood glucose is elevated it attaches to the RBC for the life of the cell.
Self Management of Blood Glucose
management technique that the diabetic uses to adjust their treatment regimen to obtain optimal blood glucose control.
It is the frequent testing of blood glucose levels and adjusting diet, activity and medications to maintain a normal blood sugar reading.
The goal of insulin therapy, or diabetic management
is to mimic the body’s natural secretion of insulin.
pattern management
(SMBG)
coordinate meals and snacks, exercise and blood glucose levels.
MANAGE SICK DAYS in diabetes
Check blood sugar more often (1-2 hrs)
Never Omit Insulin
Notify MD if sick > 1-2 days, can’t eat > 1 day, V/D > 6hr, any s/s infection, BS>250 or ketones in urine
Increase fluid intake
tonometry
The measurement of tension of a part, as intraocular tension, used to detect glaucoma.
CATARACTS facts
Most common ocular disorder
Most common cause of visual impairment
By age 80 more than half of the population have cataracts.
Leading cause preventable blindness.
Cataracts are
clouding or opacity of the crystalline lens lens that leads to gradual painless blurring of vision and eventual loss of sight.
Also common is light scattering, abnormal color perception-lens become more absorbent of blue-brown, glare sensitivity.
The Lens normally is clear and with aging becomes dense and yellow.
So the primary symptom is loss of vision.
What are the risk factors for Cataracts?
AGE (senile)
Ocular Conditions
Physical Factors
Trauma
Sunlight
Systematic Disease
Diabetes
Lifestyle Factors
Smoking
ETOH
IS THERE ANY PREVENTION of cataracts?
Educate: Prevention. Safety measures (goggles, flushing with injury). Protect: Protective sunglasses (ultraviolet rays may injure). Also education on lifestyle factors which can contribute. Smoking prevention.
Routine Screening: eye examinations as discussed with Glaucoma. Also to slow down the progression some physicians recommend use of eye vitamins such as Vitamin C, Beta Carotene and Vitamin E which are antioxidants. There are various sources available.
Control Diabetes: Good blood sugar control.
Cataracts are diagnosed with direct inspection.