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46 Cards in this Set
- Front
- Back
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Most antibody response in the periodontal tissues is __.
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polyclonal
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GCF anitbodies are produced __, not from __.
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locally; serum
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Duing healing and fibrosis of periodontal disease, __ and __ mediate fibroblast activation.
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lymphocytes and macrophages
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Complement glycoproteins are synthesized by __ and __.
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liver and macrophages
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__ is the critical complement component and account for __ of C'. The __ is the criticl feature.
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C3; 1/3; thioester
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Six regulators of C' activation have been identified and are encoded on a tight cluster on chromosome _.
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one
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What are the first of the primary leukocytes to enter the infected tissue?
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neutrophils
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The two most common opsonins are __ and __.
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C3b and IgG
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Type I LAD is the inability to express __ subunit of integrins while the Type II do not express the ligand for __ and __ selection binding. Is type I homo or heterozygous?
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beta-2; P and E; both
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During delayed type hypersensitivity what are the players in the recruitment and activation and in resolution and activation?
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IL-2 and TNF; IFN-gamma
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When is Ab-mediated hypersensitivity activated?
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during tissue destruction
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The prokaryotic proteolytics ezymes associated with streptococci are? With actinomyces? Becterioides and Porphyrmonas?
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hyaluronidase and glucuronidase;chondroitin sulfatase; collagenase
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Give 3 examples of virulence factors.
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leukotoxins, bacteriocins (streptococci), and competitions fro nutrients
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During competition fro nutrients, p.g. need __ and __ to grow and p.i. need __ and __ to grow.
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iron and hemoglobin; estrogens and steroid hormones
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Endotoxin is associated with what type of bacteria?
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gram negative
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Endotoxin interacts with host cells via __ and __. It then recruits cytokines and elicits bone resorption via __.
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CD14 and toll-like receptors; IL-1
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Another inflammatory stimulant, peptidoglycan and muramyl peptides are associated with what kind of bacteria?
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gram positive
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What are the 3 red complex organisms?
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t. denticola, p. gingivalis, and t. forsythia
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__ can cause the gums to have a blue tint.
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Subgingival calculus
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__ and __ lead to bone resorption.
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IL-1 and PGE2
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__ leads to increased production of IL-1, MMPs, and PGE2.
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IL-6
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__ gradient in gingivals sulcus facilitates the chemotaxis of PMNs.
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IL-8
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IL-8 is a __ product.
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epithelial cell
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Prostaglandin production produced __ and __ metabolites.
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cyclooxygenase and lipooxygenase
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Name 3 things that can inhibit prostaglandin production or activity.
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Steroids, NSAIDs, and COX inhibitors
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Most collagenase in inflamed gibgival tissue is eukaryotic or prokaryotic?
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eukaryotic
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__ is a risk factor for cardiovascular and pulmonary disease.
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CRP
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Enhanced __ production is associated with alveolar bone resorption and lower levels of decoy receptor.
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RANKL
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__ in inflamed tissue may be a major source of high levels of RANKL, as well as __.
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T cells; PDL fibroblasts
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Generally, the condylar angle generated by the orbiting condyle when the mandible moves laterally is larger or smaller than when the mandible protrudes straight froward?
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larger
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The father or nearer a point is to a controlling factor, the more its movement is influenced by the factor.
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nearer
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When horizontal overlap increases, the anterior guidance angle __. As vertical overlap increases, the anterior guidance table __.
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decreases; increases
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The longer radius of a curve of spee causes a flatter or more acute plane of occlusion?
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flatter
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The mandible is moving away from a horizontal reference plane at a 45 degree angle. The flatter the plane, the __greater or lesser__ will be the angle at which the posterior teeth move away from the maxillary posterior teeth and therefore the __taller or shorter__ the cusp can be.
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greater; taller
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If a radius is placed perpendicular to a horizontal reference plane, then posterior teeth located distal to the radius will need _taller or shorter cusps_ than those located mesial to the radius.
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shorter
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If the plane of occlusion is rotated more posteriorly, it can be seen that _more or less_ posterior teeth will be positioned distal to the perpendicular from the reference plane and will need shorter cusps.
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more
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What are the 3 determinants of lateral translation movement?
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amount, timing and direction
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The rotating condyle is capable of moving laterally within the area of a __ degree cone suring lateral translation movement.
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60
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The more superior the laterla trasnaltion movement of the rotating condyle, the _taller or shorter_ is the posterior cusp.
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shorter
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Do more immediate mor more progressive laterla translation movements require shorter posterior cusps?
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immediate
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The _greater or lesser_ the distance of the tooth from the rotating condyle, the wider the angle formed by the laterotrusive and mediotrusive pathways. Is this true for maxillary or mandibular teeth?
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greater; both
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The _greater or lesser_ the distance of the tooth from the midsggital plane, the wider the angle for by latero and mediotrusive movements.
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greater
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Do more anterior or more posterior teeth in the dental arch form wider angles for latero and mediotrusive pathways.
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anterior
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As the amount of lateral translation movement increases, the angle between the mediotrusive and laterotrusive pathways generated by the centric cusp _increases or decreases_.
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increases
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Do more anterolateral or more posterolateral movements of the rotating condyle produce smaller angles formed by the medio and laterotrusive pathways.
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anterolateral
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The greater the intercondylar distances, the _greater or smaller_ the angle formed by the latero and mediotrusive pathways.
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smaller
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