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17 Cards in this Set
- Front
- Back
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how well a test detects specific analyte
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analytic specificity
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ability of test to discriminate btw individuals with condition and without, frequency of negative test when disease not present
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clinical specificity
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total number of recombinant offspring divided by total number of offspring
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recombination frequency
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frequency of disease in relatives of affected proband divided by prevalence of disease in gen pop
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relative risk
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association between disease and genotype
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odds ratio
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fraction of individuals with disease who have susceptibility genotype
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sensitivity
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fraction of individuals without disease who don't have susceptibility genotype
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specificity
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proportion of individuals with susceptibility genotype who have or will develop disease
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PPV
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proportion of individuals without susceptibility genotype who don't have/will not develop disease
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NPV
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extent to which a test result is predictive of disease
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clinical validity
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extent to which test results will change what medical care a person receives
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clinical utility
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relationship between susceptibility or protective genotype/disease phenotype
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disease association
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correct assignment of genotype to person tested
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analytical validity
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ability of test to accurately detect clinical status
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clinical validity
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agreement of result with true value of analyte
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analytic accuracy
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lowest level of analyte that can be detected
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analytic sensitivity
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reproducible, agreement btw measurements
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analytic precision
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