Tb2 Pharm Unique Side Effects

Front 1

niacin

Back 1

cutaneous flushing/vasodilation, tachyphylaxis. Hepatotoxicity can occur

Front 2

fibrates

Back 2

bile stones, nausea, liver failure, myopathy, rhabdomyolysis, bile stones

Front 3

resins

Back 3

bloating, constipation, impaired absorption of vitamin K, dietary folates and drugs (digitialis, thiazaides, warfarin, pravastatin, fluvastatin)

Front 4

ezetimibe

Back 4

well tolerated

Front 5

thiazide diuretics

Back 5

hypokalemia, hyperuricemia, hypercalcemia, hyperglycemia, hyperlipidemia. Alkylates the body pH

Front 6

loop diuretics

Back 6

hypokalemia, hypocalcemia, hypomagnesemia, renal failure. Alkalyates the body pH

Front 7

potassium sparing diuretics

Back 7

hyperkalemia, renal failure. Acidifies body pH

Front 8

clonidine

Back 8

constipation, rebound hypertension, sexual dysfunction

Front 9

methyldopa

Back 9

positive coomb's test, orthostatic hypotension

Front 10

guanethidine

Back 10

diarhea, orthostatic hypotension, sexual dysfunction

Front 11

reserpine

Back 11

depression, parkinson-like syndrome

Front 12

beta blockers

Back 12

asthma in asthmatics, nightmares, vivid dreams, masks symptoms of hypoglycemia

Front 13

alpha blockers

Back 13

orthostatic hypotension

Front 14

mixed blockers

Back 14

orthostatic hypotension

Front 15

ganglionic blocker (trimethaphan)

Back 15

sympathoplegia (excessive orthostatic hypotension and sexual dysfunction)

Front 16

minoxidil

Back 16

hypertrichosis (hair growth)

Front 17

hydralazine

Back 17

lupus like syndromes

Front 18

diazoxide

Back 18

hyperglycemia

Front 19

sodium nitroprusside

Back 19

psychosis, muscle spasms, convulsions (related to thiocyante) and hypotension, metabolic acidosis, arrhythmias (related to cyanide due to metabolism of drug)

Front 20

Nifedipine

Back 20

large reflex tachycardia because it is not cardiodepressant

Front 21

verapamil

Back 21

no refelx tachycardia because it is very cardiodepressant = never use with beta blockers

Front 22

diltiazem

Back 22

some reflex tachycardia because it is only a little cardiodepressant

Front 23

ACE inhibitors

Back 23

dry cough, angioedema, hyperkalemia

Front 24

Aliskiren

Back 24

edema, elevated uric acid = gall and renal stones, gastroesophageal erflux

Front 25

acetazolamide

Back 25

allergy - drowsiness. Acidifies body pH

Front 26

thiazides + loop diuretics

Back 26

increased risk of renal carcinoma

Front 27

Spironolactone

Back 27

estrogen/testosterone mediated side effects (gynecomastia, antiandrogenic)

Front 28

nitrates

Back 28

tachycardia, orthostatic hypertension, interact with ED drugs, cause methemoglobinemia at high doses

Front 29

bepridil

Back 29

can produce torsades de pointes

Front 30

adenosine

Back 30

coronary steal in presence of CAD

Front 31

dipyridamole

Back 31

coronary steal in presence of CAD

Front 32

digoxin

Back 32

yellow green halos, blurred vision, narrow therapeutic window - prolong PR, slurr ST, widen QRS

Front 33

dobutamine

Back 33

angina pectoris, ventricular arrhythmias, increased TPR, restlessness

Front 34

dopamine

Back 34

angina pectoris, ventricular arrhythmias, increased TPR, restlessness

Front 35

amrinone

Back 35

reversible thrombocytopenia, ventricular arrhythmias

Front 36

beta-2 agonists

Back 36

body tremor

Front 37

systemic corticosteroids

Back 37

moon face, buffalo hump, abnormal glucose metabolism, mood changes

Front 38

inhaled corticosteroids

Back 38

dysphonia (myopathy of vocal cords), oral thrush (candidiasis), cough, C. pneumoniae infections

Front 39

histamine release inhibitors

Back 39

irritant effect of powder and safety issues

Front 40

Zileuton

Back 40

reversible heaptitis, can inhibit metabolism of warfarin = bleeding

Front 41

methylxandthine

Back 41

seizures at high doses, anorexia, nausea vomiting

Front 42

Omalizumab

Back 42

anaphylactic shock possible

Front 43

Class IA antiarrhythmics

Back 43

torsades de pointes (potentiated by hypokalemia), precipitation of heart failure, antichoinergic action = precipitation of acute glaucoma, urinary retention, dry eyes and mouth, blurred vision

Front 44

Class IB antiarrhythmics

Back 44

neurologic sequelae - muscle tremors, restlessness, blurred vision, insomnia. Large doses - grand mal seizures, respiratory depression, hypotension

Front 45

Class IC antiarrhythmics

Back 45

precipitate recurrent ventricular tachycardia, sudden death, worsening heart failure, CNS - dizziness, visual disturbances, headache

Front 46

amiodarone

Back 46

corneal microdeposits (photophobia), photosensitivity reactions, alterations of thyroid hormone metabolism, pulmonary fibrosis, peripheral neurophathy, ocular neuritis, liver damage

Front 47

myeloid growth factors

Back 47

pleural effusions

Front 48

ED drugs

Back 48

priapism

Front 49

heparin

Back 49

unwanted bleeding, osteoporosis in pt in renal dialysis

Front 50

warfarin

Back 50

bleeding, serious birth defects, can cause necrosis of intestines, breast tissue and other fatty tissue

Front 51

lipirudin

Back 51

bleeding, can cause anaphylatic shock

Front 52

aspirin, clopidogrel

Back 52

epigastric pain, gastrointestinal bleeding

Front 53

ticlopidine

Back 53

epigastric pain, gastrointestinal bleeding, thrombocytopenia, neutropenia

Front 54

streptokinase

Back 54

bleeding - antibodies to streptokinase are common must be cautious if pt has antibodies

Front 55

quinidine

Back 55

cinchonism