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19 Cards in this Set
- Front
- Back
T or F: the TB drugs are synergistic.
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False
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what are the 5 primary drugs that treat TB?
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- rifampin
- isoniazid - ethambutol - pyrazinamide - streptomycin |
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which the only TB drug that in not cidal?
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streptomycin
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which is the only TB drug that is not give orally?
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streptomycin
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what is the gold standard TB drug?
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isoniazid
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what drug do we always use when treating prophylatically?
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isoniazid
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what defines multi-drug resistant TB?
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resistance to rifampin and isoniazid
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where are you most likely to find MDR-TB?
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SE Asia
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what defines extreme drug resistant TB?
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resistance to rifampin, isoniazid, and some second line drugs
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what drug is most effective against extracellular actively multiply organisms?
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rifampin
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what drug is most effective against organisms that are slow multipliers inside caseous material?
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rifampin
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what drug is most effective against intracellular dormant organisms?
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pyrazinamide; it needs an acidic pH to become active
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what is the major side effect of isoniazid?
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peripheral neuropathy
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why does isoniazid give you a peripheral neuropathy?
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it depletes your body of vitamin B6
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what is the major side effect of rifampin?
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hepatotoxicity
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what drug gives you Red Man Syndrome?
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rifampin
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what is the side effect of ethambutol?
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optic neuritis
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what is the side effect pyrazinamide?
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the gout
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what is the side effect of streptomycin?
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ototoxicity
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