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19 Cards in this Set

  • Front
  • Back
T or F: the TB drugs are synergistic.
False
what are the 5 primary drugs that treat TB?
- rifampin
- isoniazid
- ethambutol
- pyrazinamide
- streptomycin
which the only TB drug that in not cidal?
streptomycin
which is the only TB drug that is not give orally?
streptomycin
what is the gold standard TB drug?
isoniazid
what drug do we always use when treating prophylatically?
isoniazid
what defines multi-drug resistant TB?
resistance to rifampin and isoniazid
where are you most likely to find MDR-TB?
SE Asia
what defines extreme drug resistant TB?
resistance to rifampin, isoniazid, and some second line drugs
what drug is most effective against extracellular actively multiply organisms?
rifampin
what drug is most effective against organisms that are slow multipliers inside caseous material?
rifampin
what drug is most effective against intracellular dormant organisms?
pyrazinamide; it needs an acidic pH to become active
what is the major side effect of isoniazid?
peripheral neuropathy
why does isoniazid give you a peripheral neuropathy?
it depletes your body of vitamin B6
what is the major side effect of rifampin?
hepatotoxicity
what drug gives you Red Man Syndrome?
rifampin
what is the side effect of ethambutol?
optic neuritis
what is the side effect pyrazinamide?
the gout
what is the side effect of streptomycin?
ototoxicity