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6 Cards in this Set
- Front
- Back
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what's the DOC for herpes keritiis?
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trifluradine - it's a thymadine analogue. also good for acyclovir resistant strains of herpes.
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what suppresses bone marrow?
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gancyclovir and Vidarabine (anti-herpes purine analogue)
note that NRTI's |
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what can you use to treat CMV?
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gancyclovir, valgancyclovir, and foscarnet.
note that gancyclovir and valgancyclovir can cause bone marrow toxicity and are contraindicated in pregnancy |
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what does interferon do?
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activate host robonucleases that degrade viral mRNA.
note that interferon causes FLU LIKE SYMPTOMS. |
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what are the side effects of NRTI's?
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myelosuppression
neutropenia anemia lactic acidosis (think tenofovir) hepatomegaly |
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NNRTI problems?
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hypersensitivity (stevens johnson).
bind directly to the RT enzyme (non-competative). No phospphorylation necessary! |
