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5 Cards in this Set
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haemophilus - what's it shaped like? how do you test for it and what kind of agar does it grow on?
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gram negative rods.
it's an obligate parasite of humans because it needs a couple things. Hematin and NAD+, to be precise. this is why the bacterium can be cultured ONLY ON CHOCOLATE AGAR. |
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what is its big bad virulence factor? type? this makes what populations particularly at risk?
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its capsule. lots of subtypes, but B = Bad.
(note - types without a capsule = nontypable, and are seen in COPD patients). aspleinics, again, are at risk, as capsule destruction depends on a functioning spleen. |
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what diseases can H. influenza cause? What age groups?
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1. Lung Infections.
2. Meningitis - most serious infection caused here. Seen in kids age 6 months - 3 years (maternal antibodies subside by six months, leaving kids vulnerable). even treated, a lot of kids end up with serious neurological problems. 2. Acute epiglotitis - can get laryngospasm upon examination. 3. Septic arthritis, usually in one joint again in kids. 4. Sepsis, again in kids. |
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is there a vaccine?
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yes! it's got a capsule, so you can make a vaccine against it.
Called HiB. |
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what's one way of picking it up in CSF?
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agglutination test with latex. can be done with really anything, but for some reason, heir doctor seems to like it with meingitis.
add your CSF to a collection of antibodies to H. influenza attached to latex. If it clumps, the bacteria is present. Rapid test. |
