Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
48 Cards in this Set
- Front
- Back
|
Dextroamphetatamine brand name
|
Dexedrine
Dextrostat |
|
|
Dextroamphetatamine isomer property
|
D-amphetatamine
More potent of the two isomers |
|
|
Dextroamphetatamine indications
|
ADHD
Narcolepsy |
|
|
Dextroamphetatamine CS class
|
CS II
|
|
|
Dextroamphetatamine PK
|
Onset of action: 1 hr
Half life 10-13 hr Metabolism: CYPs |
|
|
Dextroamphetatamine side effects
|
Aggression
Dizzyness Libido changes Anorexia |
|
|
Dextroamphetatamine doasge forms
|
Oral (tablet, capsule, liquid)
Short and long acting |
|
|
Adderall generic composition
|
Dextroamphetatamine plus
Amphetamine (L) Mixture of D&L amphetamine |
|
|
Adderall indications
|
ADHD
Narcolepsy |
|
|
Adderall PK
|
Onset : 30-60min FAST
Half life 9-14hr Metabolism: CYPs Weak inhibitor of CYP2D6 |
|
|
Adderall side effects
|
Insomnia, Headache
Decreased appetite Agitation, anxiety, N&V |
|
|
Adderall counseling for kids
|
Not for children younger than 3
|
|
|
Lisdexamfetamine dimesylate brand name
|
Vyvanse
|
|
|
Lisdexamfetamine dimesylate indications
|
ADHD only
|
|
|
Lisdexamfetamine dimesylate PK
|
Onset: 1 hr
Half life 10-13 hr Metabolism: non-CYP mediated plus intestinal |
|
|
Lisdexamfetamine dimesylate special drug properties
|
Pro-drug for D-amphetamine
Contains lysine residure which is cleaved in the intestines Result is longer duration and lower abuse potential |
|
|
Lisdexamfetamine dimesylate side effects
|
N&V, irritability
Decreased appetite, dry mouth Insomnia |
|
|
Lisdexamfetamine dimesylate dosage form
|
Oral capsule
|
|
|
Methamphetamine brand name
|
Desoxyn
|
|
|
Lisdexamfetamine dimesylate CS class
|
CS II
|
|
|
Methamphetamine indications
|
ADHD
Obesity Narcolepsy |
|
|
Methamphetamine CS class
|
CS II
|
|
|
Methamphetamine PK
|
Onset: rapid
Half life: 4-5 hr Metabolism CYP2D6 |
|
|
Methamphetamine special drug properties
|
Crosses BBB
Very lipophilic Very rapid effect High abuse potential due to fast onset and short half life N-Me group |
|
|
Methamphetamine side effects
|
Restlessness, Dizzyness
Diarrhea, Tremor, N&V |
|
|
Methylphenidate brand names
|
Ritalin, Concerta etc
|
|
|
Methylphenidate indications
|
ADHD
Narcolepsy |
|
|
Methylphenidate CS class
|
CS II
|
|
|
Methylphenidate PK
|
Onset: 2 hr
Half life: 3-4 hr Metabolism: hepatic, some CYP |
|
|
Onset: rapid
Half life: 4-5 hr Metabolism CYP2D6 side effects |
Insomnia, N&V
Decreased appetite |
|
|
Methylphenidate formulations
|
Oral (tablet, capsule, liquid)
Transdermal (Daytrana) |
|
|
Modafinil brand name
|
Provigil
|
|
|
Modafinil indications
|
Narcolepsy
Shift work disorder |
|
|
Modafinil CS schedule
|
CS IV; less addictive
|
|
|
Modafinil PK
|
Onset: 2-4 hr
Half life 15 hr Metabolism: CYP3A4 Inducer and inhibitor of many CYPs |
|
|
Modafinil key drug property/drug mechanism
|
"Wakefulness promoting agent" different from other stimulants
Results in increase in histamine in hypothalamus |
|
|
Modafinil drug class
|
Non-AMPT
|
|
|
Phenteramine brand name
|
Adipex
|
|
|
Phenteramine indication
|
Obesity
|
|
|
Phenteramine CS class
|
CS IV
|
|
|
Phenteramine PK
|
Half life 20 hr
Metabolism: hepatic |
|
|
Phenteramine doasge forms
|
Oral (capsule, tablet)
|
|
|
Phenteramine side effects
|
Heart palpitation
Insomnia, headache Nausea, anxiety |
|
|
ADHD meds
|
Dextroamphetamine
Dextroamphetamine+ AMPT Lisdexamfetamine Methamphetamine Methylphenidate DDLMM-"Dumb luck Mom" |
|
|
Narcolepsy meds
|
Dextroamphetamine
Dextroamphetamine+ AMPT Modafinil Methamphetamine Methylphenidate DDMMM "Naps: 2 Down, 3 More" |
|
|
ADHD only drug
|
Lisdexamfetamine
|
|
|
Narcolepsy only drug
|
Modafinil
|
|
|
Apetitie supression drugs
|
Methamphetamine
Phenteramine |
