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23 Cards in this Set

  • Front
  • Back
Characteristics of Tuberculosis (TB)
-contracted by inhalation of Mycobacterium tuberculosis (strict aerobe, stained with acid fast d/t to mycolic acid in cell wall)
2 types:
1 Primary TB (Ghons complex)
2. Secondary (reactivation) TB (no Ghons complex)
What is the screening method used for TB?
PPD: Purified protein derivative
-is an intradermal test
-DOES NOT distinguish active from inactive disease
What is the location of Primary TB?
Upper part of the lobes or lower part of the upper lobes
What is the prognosis of Primary TB?
Usually resolves:
-produces calcified granuloma or area of scar tissue
-may be a site of origin for secondary TB
Where are the site of reactivation TB?
Involves one or both apices in the Upper lobe (ventilation is greatest at this site which helps TB grow)
Characteristics of reactivation TB?
-occurs d/t reactivation of a previous TB site
-Produces cavitary lesions d/t the release of cytokines from memory T-cells
What organisms produce Cavitations in the upper lobe of the lungs?
TB (secondary)
Histoplasmosis
Klebsiella
Squamous cell carcinoma
What are the symptoms of TB?
Fever
Drenching night sweats
Weight loss
What are some of the complications associated with TB?
-Can spread to other areas within the lungs
-can spread to extrapulmonary areas Via Pul. vein
-
Can cause:
1. Massive hemoptysis
2. Bronchiectasis
3. scar carcinoma
What is the most common extrapulmonary site for TB to spread?
Kidney
Can also spread to:
Liver=causing granulomatous hepatitis
Vertebra=Pott's disease
Charcateristics of Mycobacterium avium-Intracellulare complpex (MAC)?
-Its an atypical Mycobacterium
-MCC of TB in AIDS patients (opportunistic infections=low CD4 count)
What is the most common cause of Lung Abscesses?
Aspiration of oropharyngeal material
What kind of individuals are lung abscesses usually associated with?
-usually seen in street/homeless people
-occurs in people with depressed cough reflexes (after anesthesia)
What is the composition of a lung abscess?
Mixture of aerobic/anaerobic stretococci and staphylococci, Prevotella, Fusobacterium
What are some symptoms seen in a person with a lung abscess?
Spiking fever with productive cough (foul-smelling fever)
chest x-ray shows cavitations with an air-fluid level
What are some complications associated with lung abscesses?
1. bacterial pneumonia (Staph aureus, Klebsiella)
2. septic embolism (Infective endocarditis)
3. Obstructive lung neoplasia
What are the aspiration site in the lungs when a person is LAYING ON THEIR RIGHT SIDE?
1. posterior segment of the right-upper lobe
2. right middle lobe
What are the aspiration site in the lungs when a person is LAYING ON THEIR BACK?
Superior segment of the right lower lobe
What are the aspiration site in the lungs when a person is STANDING OR SITTING?
Posterobasal segment of the right lower lobe
What are the aspiration site in the lungs when a person is LAYING ON THEIR LEFT SIDE?
lingular of the lung
What is themajor origin/site of a pulmonary embolus?
Femoral Vein
What are some of the risk factors that may lead to a Pulmonary thromboembolism?
Stasis of blood: prolonged bed-rest/flights
Hypercoagulative states
What are the two sizes of emboli that plug the pulmonary vessels?
1. Large emboli
-occludes major vessels--->saddle embolus (deadly)

2. Small emboli
-occludes med-size vessels and small pulmonary vessels
(usually doesn't produce an infarct only if there's a pre-existing condition (smoking))