Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
13 Cards in this Set
- Front
- Back
|
where is the biosynthesis of nucleotide?
|
cytoplasm
|
|
|
PRPP
|
phosphoribosyl pyrophosphate is derived from ribose-5-p
|
|
|
IMP
|
inosine monophosphate serves as the common precursor of AMP and GMP synthesis.
|
|
|
Gln, Glym Asp
|
Are donors of C and N atoms.
|
|
|
what is a source of C
|
CO2
|
|
|
where are the C1 units
|
via tetrahydrofolate
|
|
|
what is the salvage pathway
|
purines from normal turnover of cellular NA can be converted to nucleoside triphosphate
|
|
|
Substrates of purine nucleotides synthesis
|
purine bases, PRPP, ATP
|
|
|
where is carbamoyl phosphate found in pyrimidine synthesis?
|
cytosol and its an important regulatory step
|
|
|
where is pyrimidine synthesis therefore done?
|
pathways start in cytosol, but formation of ortotate occurs in mitochondrion, orotate is linked by PRPP>OMP>UMP
|
|
|
how is carbamoyl phosphate synthetase II regulated
|
PRPP activates it
UTP inhibits it |
|
|
salvage pathway of pyrimidines
|
pyrimidine nucleosides are phosphorylated (ATP) to nucleotides
|
|
|
what does UMP from
|
it forms UTP, which forms CTP and TTP
|
