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11 Cards in this Set
- Front
- Back
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Synapsin I
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Dephosphorylated --> binds vesicles to cytoskeleton
Phosphorylated with increase of Ca --> releases vesicles |
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Rab 3A
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GTPase that propels vesicle to the active zone
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Synaptotagmin
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Calcium sensor that triggers Ca2+ exocytosis
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NSF
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ATPase that releases SNARE complex
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SNAPs
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binds to NSF and SNARE proteins
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vesicular SNAREs (v-SNAREs, VAMP) [example]
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Synaptobrevin
Bind to t-SNAREs |
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target membrane SNAREs (t-SNAREs) [example]
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Syntaxin and SNAP-25
Bind to v-SNAREs |
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Neurexin
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Interacts with vesicle proteins
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Tetanus
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v-SNAREs
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Botulinum
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t-SNAREs
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alpha-latrotoxin
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Binds neurexin and causes huge release of neurotransmitter
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