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21 Cards in this Set
- Front
- Back
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What are the 3 phases of wound healing?
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-inflammation
-proliferation -maturation |
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What happens in the inflammation stage of wound healing?
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-bleeding (RBC, WBC)
-coagulation (fibrin) -platelet activation (cytokines) -comlement activation (cytokines) |
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What cells do cell recruitment in the inflammation phase?
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macrophages (they clean up wounds)
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What does cell recruitment in the proliferation phase?
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fibroblasts
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Fibroblasts form what?
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collagen extacellular matrix
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What 3 things occur during the proliferation phase of wound healing?
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-new blood vessels form
-new epithelium form -wound contracture |
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What 4 things happen in the maturation phase of wound healing?
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-remodeling of collagen
-increase in tensile strength -decreased cellularity -decrease vascularity |
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What are some things that can help promote healing by primary intention?
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-sutures
-steri strips -staples -glue |
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What does it mean when healing is done by secondary intention?
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wound edges are not brough together or approximated
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What are some examples of a wound that would be healed by secondary intention?
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-contaminated wound (abscess)
-large or irregular defect |
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What does healing by delayed primary mean?
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that wound edges are brought together, but not at the time of wounding (aka they are brought together later)
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In surgical pts, where do germs come from?
give examples |
the pt
-intestinal organisms during bowel surgery -gallbladder organisms during cholecystectomy -vaginal organisms during hysterectomy |
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What is meant by a Type 1 or clean operation?
examples? |
no contact with normal flora except skin
-hernia repair -breast biopsy |
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What is ment by a Type 2 or clean/contaminated operation?
examples? |
-minimal contact with normal internal flora
-gastric sx -elective cholecystectomy -elective colectomy wiht prepped bowel |
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What is a Type 3 or contaminated operation?
examples? |
-modest contact with pathologic flora
-appendectomy for purulect appendicitis -emergent cholecystectomy |
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What is type IV or infected operation?
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-extensive contact with pahtologic flora
-drainage of abscess -appendectomy for perforated appendicitis |
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What are 3 things that are determinants of infections?
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-virulence of organisms
-number of organisms -host defense |
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What are the 3 classifications of that SSI's are put into?
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-incisional
-organ -other organs and spaces manipulated during an operation |
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What are the 2 subclases of incisional infections?
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-superfical
-deep |
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What is a key disinction to make when deciding how to treat an SSI?
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-local infection without systemic manifestation vs a systemic manifestation
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What is the tx for a superficial wound without systemic manifestations?
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-open wound, drain the purulence
-no need for systemic antibiotics |
