Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
17 Cards in this Set
- Front
- Back
|
edema dz
a. epidemiology b. pathogenesis c. signs |
a. reoccurs in each subsequent group
thorough environmental cleaning doesn’t dependably prevent occurrence b. Shiga-like (vero) toxin --> arteritis --> edema --> necrosis ST or LT toxins --> scours E. coli: F18 or K88 attachment pilli c. onset: 10 d. post-weaning CNS signs, palpebral edema, gaunt, +/- diarrhea, penmates NOT affected |
|
|
edema dz
a. lesions b. dx c. tx d. prevention |
a. edema seen in palpebrae, forehead, greater curvature of stomach, mesocolon (post-weaning)
brainstem necrosis --> residual CNS deficits b. isolation from gut, PCR, histopath c. injectable ABs & dexamethasone: poor response once clinical signs begin d. ↑ fiber, ↓ energy, soybean meal, fish meals inoculate at weaning: competitive colonization (non-toxigenic F18 E. coli in water) |
|
|
salmonellosis
a. epidemiology b. prevention |
a. transmission: fecal contamination of feed, environment, equipment, lagoon water
stress related dz long term asymptomatic carriers: non-clinical infections common! b. avirulent live S. cholerasuis oral vaccine no water or feed ABs! minimize stress |
|
|
S. cholerasuis
a. epidemiology b. pathogenesis c. signs |
a. seen in nursery pigs thru finishing: most common early to mid-finishing
b. bacteria survives w/in MPs & PMNs --> enters systemically via Peyer’s patches or tonsils --> diffuse pneumonia, hepatosplenomegaly, diffuse necrotic colitis LPS endotoxemia --> circulatory disruption (cyanosis of ears, legs, underline) --> circulatory collapse & death c. fever (105-107º F), piloerection, hyperemia, depression cyanosis scours ~3 d. post-onset (no blood or mucus in feces) pneumonia common high mortality rate |
|
|
ddx for post-weaning scours
|
edema dz
Salmonella cholerasuis Salmonella typhimurium ileitis Serpulina hyodysenteriae gastric ulcers hemorrhagic bowel syndrome Trichuris suis (whipworms) |
|
|
S. cholerasuis
a. dx b. tx |
a. bacteria isolated from lung, GB, or systemic ln’s: diagnostic
bacteria isolated from tonsil = diseased or carrier b. must tx w/ ABs (Ceftiofur) IM early: few ABs effective |
|
|
S. cholerasuis
a. dx b. tx |
a. bacteria isolated from lung, GB, or systemic ln’s: diagnostic
bacteria isolated from tonsil = diseased or carrier b. must tx w/ ABs (Ceftiofur) IM early: few ABs effective |
|
|
S. typhimurium
a. dx b. tx |
a. dx requires: clinical signs, gross lesions, histopath lesions, & no other pathogens isolated
isolation or positive PCR does not confirm dx b. will respond to ABs in water if effective drug chosen RESISTANT to most approved ABs |
|
|
ileitis
a. etiology b. 4 syndromes c. characteristic lesion d. dx |
a. Lawsonia intracellularis
b. porcine proliferative enteropathy porcine intestinal adenomatosis necroproliferative enteritis/necrotic ileitis porcine hemorrhagic enteropathy c. submucosal gland hyperplasia lesion location: ileum > jejunum > colon d. gross lesions & hx histopath: submucosal gland hyperplasia PCR: false (-) common |
|
|
porcine intestinal adenomatosis (PIA)
a. signs b. lesions |
a. affects piglets from weaning to 12 wks
off feed, periodic scours, wasting (5-10 d. after onset) many asymptomatic cases b. submucosal gland hyperplasia no surface damage to mucosa! |
|
|
necroproliferative enteritis/necrotic ileitis
a. signs |
affects pigs 8-20 wks
watery rust colored diarrhea +/- fibrin casts in feces, wasting many asymptomatic pigs w/ gut lesions |
|
|
porcine hemorrhagic enteropathy
a. signs b. lesions |
a. affects pigs 8-20 wks
watery rust colored diarrhea +/- fibrin casts in feces, wasting many asymptomatic pigs w/ gut lesions b. submucosal gland hyperplasia blood in SI, normal mucosa, wall thickened spiral colon contents black & tarry diffuse gastric ulceration |
|
|
ileitis
a. tx b. prevention |
a. ABs: injectable until fully only water medication
-neomycin, tylosin, mecadox, bacitracin MD b. no ABs or chlorine in water! pulse AB tx: enables development of “natural” immunity while controlling dz, do in herds w/ consistent problem & exposure |
|
|
Serpulina hyodysenteriae (swine dysentery)
a. epidemiology b. lesions c. signs |
a. spirochete
shed in huge numbers by pigs: recovered pigs are long term carriers/shedders b. mucohemorrhagic/necrotic colitis typhlitis mixed infections common: S. typhimurium, L. intracellularis c. mucohemorrhagic diarrhea in grow-finish blood frequently not seen, just green-gray mucoid diarrhea: recurs every 21 d. marked wt. loss, significant ↓ in feed efficiency & avg. daily gain |
|
|
Serpulina hyodysenteriae (swine dysentery)
a. dx b. tx c. eradication d. prevention |
a. lesions only in colon
histopath culture hemolytic spirochetes from colon, rectal swabs b. injectable ABs, then oral in water or feed cidal: carbadox (mecadox), tiamulin c. tx whole herd w/ bacteriocidal drugs for 21 d. phased building depopulation & sanitation during summer: heat & drying kills organism repopulate w/ AB treated pigs rodent eradication d. infected herds: chronic in-feed ABs isolate all new herd additions: tx w/ bacteriocidal drugs for 21 d. |
|
|
How can you differentiate the causes of fibrinonecrotic colitis in finisher pigs?
|
Lawsonia intracellularies: ileal proliferative lesions in other pigs in group, rusty feces, AB response pattern
Salmonella spp.: pneumonia, septicemia = S. cholerasuis NO or poor response to ABs SI diarrhea, enlarged mesenteric ln w/ congested cortex, non-mucoid colitis, diffuse thin mucosal necrosis in colon suggestive Serpulina often very mucoid diarrhea +/- blood flecks early lesions: mucohemorrhagic colitis & typhlitis later lesions: obvious adherent low fibrinonecrotic colitis AB response pattern suggestive: 21 d. “cycle” or return if ABs removed |
|
|
Salmonella typhimurium
a. signs b. lesions |
a. watery yellow diarrhea to grey/green loose stools w/ no blood or mucus
pigs become gaunt, unthrifty, depressed multiple reoccurrences possible sequela: rectal stricture b. mucosal necrosis of colon hypertrophy of lymphoid follicles + possible necrosis = button ulcers (in spiral colon) |
