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50 Cards in this Set

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Etiological agent(s) of Edema disease
E. coli O138
E. coli O139
E. coli O141
Etiological agent(s) of Colibacillosis
E. coli K88
E. coli K99
E. coli F 41
E. coli 987 P
Etiological agent(s) of Rotavirus
Rotavirus
Etiological agent(s) of Salmonellosis
Gram Neg Rod
Salmonella cholerasuis
Salmonella typhimurium
Salmonella typhisuis
Salmonella derby
CS:
Sudden and explosive intermittent presentation of weanling piglets with neurological signs, about 10% are affected.
Edema dz
What's the pathognomic lesion for Edema dz?
Renal cortical ischemia & medullary engorgement
Edema of eyelid
How would you dx Edema dz?
Culture the specific E. coli stains (O138, O139, O141)
Lesions
HX & CS
How would you tx Edema dz & what would you tell the farmer to do?
You would give the piglets Apralan or Tetracycline
(if not responsive, you'd give Neomycin or Fluoramphenicol -not approved in food animal)
(or BMD -bacitracin, Methylene, Disalicylate -ok in food animal)

Tell farmer to improvemanagement - reduce feed given to piglets to 1 pound per pig per day.
Add alfalfa, oat, or barley
Farmer calls, says neonate piglets have watery- yellow diarrhea. Some of the weanlings aren't putting on weight either.
What do you suspect?
Colibacillosis
You are given several piglets from a local farm for necropsy. Some piglets have no obvious lesions, though they are thin. On some others you note food in the stomach, congestion of small intestine. What do you suspect?
Colibacillosis
For a farmer with an outbreak of colibacillosis, what do you do and what do you tell him to do?
You would treat the whole litter quickly with Gentamycin (ok in neonates) or tetracycline or Apralan.

You tell farmer to improve husbandry by increasing ventilation & temperature, reducing stress & humidity.

Vaccination options
• Kohler/Autogenous Milk vaccine -give to sow to give passive immunity to piglets
•Porcimmune -not a real vaxx -give to piglets
•Porcine Ecolizer -a real vaxx - given to sow 2-4weeks before farrowing
DDX for Edema dz
Salt poisoning
Pseudo Rabies
Erysipelas
Classical Swine Fever/Hog Cholera
DDX for Colibacillosis
Rotavirus
Pathogenesis for Edema dz
Anaphylactic shock -->
Increased vascular permeability & edema of brain and other areas
pathogenesis for Colibacillosis
LT acts on Adenylcyclase to --> ATP
ATP acts on cAMP
cAMP alters membrane permeability to secrete H2O & Na --> Acidosis & Dehydration
Serotypes of Rotavirus
A-G
MC: A,B,E,C
MC of MC: A
A farmer calls you saying piglets broke with yellow-white diarrhea and are not putting on weight. A few have died. Both pre and post weaned piglets are affected. What do you suspect?
Rotavirus
A farmer brings you several dead piglets for necropsy. You find the all sections of small intestine to have thin walls and shortened villi and distention of cecum & colon. What do you suspect?
Rotavirus
What would you do for a farmer who has an out break of Rotavirus, what would you tell him?
You would provide supportive treatments. Electrolytes and glucose and start broad spectrum ABX. b12 injection too.

You tell the farmer to fumigate the environment with 10% formalin or disinfect with sodium hydroxide, lye, Chlorine or iodine

Vaccinate with scour shield 7 and 14 d and sow 2-4 weeks before farrowing.
A farmer's feeder pigs have respiratory distress, SQ skin hemorrhages, cyanosis, CNS signs and a fever. What do you suspect?
Salmonellosis
(1) Acute Septic form
You are given several pigs for necropsy. You fine splenomegally, hemorrhages in LN, Necrosis in Cecum and Colon. You note "button ulcers" in intestines. What do you suspect?
Salmonellosis
What would you do for an outbreak of Salmonellosis, what would you tell the farmer?
REPORT IT!

You'd give piglets ABX (furacin, neomycin, carbodox, tramulin, naxcel or tetracycline)

Tell farmer to increase ventilation, maintain strict sanitation (Disinfect with Cl, Iodine or Phenol based solvents)
AIAO
OSEW
Quarentine new pigs 30-60 d
Culture @slaughter
ELISA brook stock


Vaxx for intermediate infection
Etio for Swine Dysentery
Brachyspira hyodysenteriae
List the name changes for Etio of Swine Dysentery
1st called: Vibrio
2nd called: Campylobacter
3rd called: Serpulina
4th called: Treponema
Now called: Brachyspira hyodysenteriae
What is Brachyspira hyodysenteriae?
Etiological agent for Swine dysentery.
It's an Anaerobic Spirochete
What are the 3 forms of Salmonellosis & what do you see with each?
1) acute septic
-septicemia & respiratory CS
-Cyanosis & CNS
-Fever 106-108
-SQ hemorrhages (ear and abdomen)

2) Chronic enteritis
-don't die, just linger and waste away
-Diarrhea
-Melena

3) Asymptomatic carriers
-no CS
-just shed the bacteria
What age does Swine dysentery affect?
Grower finishers (8-12 weeks)
Does NOT affect neonates
what are the CS of Swine dysentery?
Mucopurulent to bloody Diarrhea
(early = frank blood)
(later = tarry)
Gaunt & tucked up
Fever 106-108
Anorexic (1/2 to no feed)
What are the lesions of Swine dysentery
necrotic inflammation of cecum & colon
yellow to grey diphtheritic surfaces +/- hemorrhage
Large intestine -rice water
Ileocecal demarcation
mesenteric LN -edema and hyperemia
A farmer presents you with piglets for necropsy complaining of history of frank blood in feces and poor appetite. You necropsy and find necrotic inflammation of cecum and colon. What do you do and what do you tell the farmer to do?
you suspect swine dysentery

You start treatment ASAP
Antibiotics (ie. tylosin, or virginiamycin)
Tell farmer to control traffic/rodents, improve sanitation (use footbaths and proper cleaning agents)
Depopulate
Next time may want to use Hy-Guard vaccine at 8 weeks
Etio of TGE
Corona virus
(18 hour incubation)
What ages is affected by TGE
all ages
if less than 2 weeks get 100% mortality
What are cs of TGE
Explosive outbreak
Vomiting/diarrhea, inappetance
Agalactia
Etio of porcine epidemic diarrhea
Corona
CS of porcine epidemic diarrhea
watery diarrhea
~50% morbidity
not usually much of a problem
Lesions of Porcine epidemic diarrhea
Necrosis of back muscles
dehydration and fluids in small intestine
Atrophy of villi/fused villi
Etio of Clostridium
Clostridium A & C in pig
Clostridium C & D in cow

A is mild
C = 3 day pig

Alpha toxin = fluid
Beta toxin = cytopathic
CS of clostridium
Bloody diarrhea
Lots of gas
Sick in hours, dead in 8 "3 day pig"
if no immunity = 100% mortality
lesions of clostridium
Pseudo membranes in small intestine
intense hemorrhage
serosanguinous fluid
GAS
blood in pleural cavity
A farmer presents you with some piglets for necropsy with an acute history of sick with bloody diarrhea, then died. On necropsy you find blood in the pleural cavity, pseudomembranes in small intestine and lots of gas. What do you suspect. What do you do and what do you tell the farmer?
You suspect clostridium A & C

You give antibiotics (bacitracin, tyosin)

You tell the farmer it's spread by carriers, fomites and orally.
Next farrowing period he may want to give Bacterin -a toxoid-to the sow before farrowing.
Etio of Atrophic Rhinitis
Bordetella bronchiseptica with Pasteurella multocida
CS of atrophic rhinitis
hemorrhage from nose
Twisting nasal bones
What are the 3 requirements to get twisted nasal bones
Infected with Atrophic rhinitis when less than 3 weeks old

Infected with a virulent strain

Infected for an adequate duration
To diagnose atrophic rhinitis, what would you do
if < 5 mo -section at 1st premolar
if > 5 mo -section at 2nd premolar
What would you do for atrophic rhinitis, what would you tell farmer?
You could give Tylosin or Chlortetracycline or sulfathiazole

You could vaxxinate the sow and babies at 1-4 weeks
(ok to give even if not necessarily an issue)

Tell farmer to use different management techniques:
AIAO
Cull and market any with CS
4 point program
Etio of Inclusion body rhinitis
Herpes
What the presenting difference btw Atrophic rhinitis and Inclusion body rhinitis?
Atrophic rhinitis presents with bloody nasal discharge

Inclusion body rhinitis often subclinical
Etio of Necrotic Rhinitis
Speropherous necrophorus
Etio of Porcine Respiratory and Reproductive syndrome
Arterivirus (related to lelystad virus)
CS of PRRS
Repro:
low conception
late term abortion
still borns/weak
mumified fetus
"stall out" nursery
Resp:
Diffuse interstitial pneumonia (cough)