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41 Cards in this Set

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Endemic

Not alarming, few people more then normal/ present in region/community only

Epidemiology

Study of the frequency and geographic distribution of diseases and what contributes to their spread

Contributing factors to spread of disease

Population overcrowding, poor sanitation,lack of immunization,and methods of transmission

Pandemic

Word wide disease

Epidemic

Disease that occurs with a greater that normal incidence of reported cases ex . Typhoid cholera and dysentery

First line of defense

External and internal barriers ex. Skin, mucous,secretions/ all openings in body

What happens when skin damaged ?

Creates opening for microbes ex. Burns wounds

Exception

Subaceous glands have acidity that either kill or stops the growth of bacteria (oil producing glands)>ph low very aciditic, digestive secretions in the intestines are highly acidic/ create alkaline (which kills microbes)

Second line of Defense

Circulatory/chemical defense

Examples of 2nd line defense

Phagocytes (white blood cells) assist antibodies and other blood proteins by fighting back with against viruses and tumors with fever production, iron, and with the bodies response to injury or infection (inflammatory response)- garbage collectors of human body

Fever (2nd response)

Produces pyrogenic secretions that trigger the fever

Inflammatory Response (2nd Response)

Bodies response to injury, bacterial toxins,and pathogens by intiating this response

THE GOOD Process of inflammatory response

Damaged blood vessels will expand because of its dying /help needed/ more cells come/more eating there/more garbage eaten/more oxygen/more food/all expense of dialation of blood cell

Bad Reaction of inflammatory Response

Area of body turns red because more blood/body feels hot and pain/becomes swollen/if last more then 3-5 days if not anti-inflammatory drug needs to be given/if not loss of function can occur

Third Line of Defense

Immune response

Examples of third Line of Response

Antigen-Antibody Response-Antibody- Immunity

ANTIGEN

anything that goes into your body and causes you harm ex spores virus fungi allergent/antigen enemy antibody is the army

Antibody

Takes several weeks to build up /arky for your body against antigen

Naturally aquired Active Immunity

Sick= because of any antigen- develop antibodies to fight antigens

ARTIFICAL AQUIRED ACTIVE

Vaccine recognizes ID produces antibodies to fight weakened flu/ attenuation = weakened version of disease/ not the infection causing just the disease

Type 4

Does not involve antibodies /cell mediated / contact dermatology / allergic dermatitis /ppd test

Antibody classifications

IgA,igD,igE,igg,igM

IgA

The technique is membranes and internal body cavities against infection known as the secretory antibody since it is found in the saliva colastrum tears bloodstream and intestines. Prevent pathogens from adhering to mucosal surfaces

IgD

Function not well understood

IgE

Is the cause of allergies anaphylaxis drug sensitivity and immediate hypersensitivity in the skin test reactions. Call of rash or hives in allergic reactions runny nose and itchy eyes of hayfever asthma and shock in anaphylaxis.

IgG

Most abundant and smallest of the antibodies.

IgM

Largest antibody. First antibodies formed in response to infection.

Examples of type 1 Hypersentivity

This includes allergic responses to hey fever animals grasses and trees. Other responses under this type includes hives due to allergic food allergies drug allergies allergic response to insect bites or stings and anaphylactic shock type 1 allergic responses can be most dangerous and life threatening the reactions of ige antibodies causing this reaction.

Examples of type 2 allergic responses

This involves IgG or IgM antibodies and complement. Type two responses are cytotoxic responses when the wrong blood is given to a patient during a blood transfusion and Rh incompatibility reactions sometimes seen in pregnant females

Examples of type 3 allergic response

This involves IgM IgG antibodies neutrophiles and complement type 3 reactions are seen in autoimmune diseases such as rheumatoid arthritis

Natural Aquired Passive Immunity

Performed antibodies formed in another individual ex breast milk mother - baby

Fourth kind of immunity

Antibodies created in an animal then frozen till needed for snake bites venom- patient gets injection of performed antibody because antiboidies take several weeks to manifest in human body and the need is emergency no time to wait life or death

Which is faster

Secondary response is faster then first response because of memory cells - creates memory of first attack to be prepared for next attack

Humoral immunity

When the antibodies are involved

Cell-mediated immunity

When the lymphocites are directly involved immunity and there is no antibody involvement

Hypersensitivity reactions

Abnormal/body overreaction

Hypersensitivity reactions

Abnormal/body overreaction

Type 1

Most dangerous/life threatening analyphlatic shock

Type 2

Cystoxic/miss matched blood tranfusion

Type 3

Autoimmune against self

Type 3

Autoimmune against self