Surgical Meds, Fen

Front 1

anesthetic that increases cardiac work and O2 use, secretions, and blood pressure, but doesn't cause respiratory depression

Back 1

Ketamine

Front 2

Inhaled anesthetic with renal toxicity

Back 2

methoxyflurane

Front 3

Inhaled anesthetic with hepatotoxicity

Back 3

halothane

Front 4

antibiotic prolonging neuromuscular blockade

Back 4

clindamycin

Front 5

long-acting SST analog

Back 5

octreotide

Front 6

Digoxin: MOA

Back 6

Decreases Na/K/ATPase to increase Ca available to myocytes.

Slows AV conduction

Does not increase O2 consumption.

Front 7

Digoxin: side fx

Back 7

ischemic gut, decreased splanchnic flow

Front 8

metyrapone: MOA

Back 8

blocks 11 β-OHase so no cortisol is made. Stimulates ACTH

Front 9

metyrapone: use

Back 9

to dx adrenal insufficiency

Front 10

aminoglutethimide: MOA

Back 10

blocks production of steroids derived from cholesterol

Front 11

Leuprolide: MOA and indication

Back 11

GnRH agonist, causes medical orchiectomy

Front 12

Misoprostil: MOA

Back 12

replaces PGE2 (cryoprotective) for pts on NSAIDs, reduces PUD

Front 13

FeNa, Urine Na, and BUN/Cr results in pre-renal failure

Back 13

FeNa <1%

Urine Na <20

(kidneys are working and conserving Na to conserve volume)

BUN/Cr >30 : nitrogen getting recycled

Front 14

What secretion has highest K concentration?

Back 14

Salive>gastric>pancreatic/duodenal

Front 15

branched chain amino acids: what are they?

Back 15

Ile, Leu, Val

Front 16

branched chain amino acids: where metabolized?

Back 16

muscle

Front 17

25-OHase to activate vitamin D found in ______; 1-OHase found in ____

Back 17

Liver; Kidney

Front 18

increases calcium binding protein to increase intestinal absorption of calcium

Back 18

vitamin D

Front 19

Vitamin __ reverses adverse effects of steroid on wound healing

Back 19

A

Front 20

Total body water higher in (men, women)

Back 20

men (women have more fat)

Front 21

Total body water is _____% of weight; ___% of weight caused by water is intracellular; ___% is intestinal, ___% is plasma

Back 21

60; 40; 15; 5

Front 22

Basal calorie expenditure calculation

Back 22

25 kcal/kg/day

Front 23

___g protein/kg/day needed

Back 23

1

Front 24

Respiratory quotient

Back 24

ratio of CO2 produced/O2 consumed.

Varies depending on whether fat or carbs used

Front 25

Respiratory quotient
if
A) fat used
B) carbs used

Back 25

A) 0.7
B) 1.0

Front 26

Preferred fuel of colon

Back 26

Short chain fatty acids

Front 27

Preferred fuel of small bowel

Back 27

Glutamine (most common amino acid in bloodstream)

Front 28

What causes decreased glutamine?

Back 28

Stress as glu goes to kidney to form ammonium to help acidosis

Front 29

Which fats go to portal system with AAs and Carbs?

Back 29

Only Short and Medium Chain Triglycs

Front 30

Chromium def: sx

Back 30

hyperglycemia (relative diabetes)

neuropathy

Front 31

Zinc def: sx

Back 31

Hair loss

Poor healing

Change in taste

Perioral rash

Front 32

Phosphate def: sx

Back 32

Weakness (resp)

Encephalopathy bc P needed for ATP

Front 33

Copper def: sx

Back 33

anemia

neutropenia

Front 34

Linoleic acid def (essential FA def) : sx

Back 34

dermatitis

hair loss

change in vision

Front 35

Vit A def: sx

Back 35

can decrease Vit C stores

Front 36

Cori cycle: what goes where?

Back 36

Glucose --> lactate ---> to liver ---> back to glucose

Front 37

What happens to brain energy usage in starvation?

Back 37

uses ketones from FAs

Front 38

What happens in late starvation?

Back 38

Gluconeogen shifts to kidney as liver is depleted of ALANINE

Front 39

in late starvation, Gluconeogen shifts to kidney as liver is depleted of _____

Back 39

alanine

Front 40

causes of increased anion gap metabolic acidosis

Back 40

MUDPILES

Methanol
Uremia
DKA
Paraldehyde
Lactic acidosis
Ethanol
salicylates

Front 41

anion gap calc

Back 41

Na - (Cl + HCO3)

normally <12

Front 42

how does alkalosis cause hypo[K+]?

Back 42

Decreased [H+] causes H+ to come out of cells via H/K exchanger. K+ goes into cells and into urine.

Front 43

Hyperglycemia (lowers, increases) Na

Back 43

LOWERS

Front 44

How to correct Na for hyperglycemia?

Back 44

For every 100 glucose over 100, add 2 to [Na]

Front 45

Low __ and ___ cause hyperexcitability and increased reflexes

Back 45

Ca and Mg

Front 46

How does low Mg affect PTH?

Back 46

inhibits PTH. Replace Mg if there is difficulty correcting patient's Ca

Front 47

Replace _ if there is difficulty correcting patient's Ca

Back 47

Mg