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23 Cards in this Set

  • Front
  • Back
what are the 3 main types of skin cancer?
basal cell 70%
squamous cell 25%
melanoma 5% (most lethal)
what are some etiologies of skin cancer?
solar radiation
chemical exposure
burn scars
chronic draining skin infections and fistulas
virus (EBV)
what is the MC type of skin cancer?
BCC: basal cell 70%
an aggressive ulcerating squamous cell carcinoma presenting in an area of previously traumatised [1], chronically inflamed [2], or scarred skin [3]. They are commonly present in the context of chronic wounds including burn injuries, venous ulcers, ulcers from osteomyelitis [4], and post radiotherapy scars.
marjolin's ulcers
a genetic disorder of DNA repair in which the body's normal ability to remove damage caused by ultraviolet (UV) light is deficient. This leads to multiple basaliomas and other skin malignancies at a young age. In severe cases, it is necessary to
xeroderma pigmentosum
where does basal cell carcinoma arise from?
basal layer of germinating cells of the skin epithelium or epithelial appendages: hair follicles, sebaceous glands
what are the 3 major varieties of BCC?
morphealike or fibrosing
the higher the number of undifferentiated cells is the worse the prognosis is. TRUE/ FALSE?
where is the most common site for SCC?
lower lip. 75%
where do squamous cell carcinomas arise from?
Arise from any area of squamous or transitional epithelium. esp. junction of skin and mucus membranes
what is the term for the skin condition that is characterized by chronic scaling and occasionally a crusted, purple or erythematous raised lesion that is carcinoma in situ that has not broken through the epidermal-dermal junction?
Bowen's Disease
where do melanomas arise from?
neural crest tissue
what are some characteristics of malignant skin lesions?
change in pigmentation
rapid growth
pain, itching, other discomfort
raised borders
what is the MC skin carcinoma?
BCC: middle 1/3 of the face
usually a painless growth, that spreads by extention and is known as the "rodent ulcer"
what are the 4 main treatments for BCC?
topical cream: 5-flurouracil
what are the 3 main types of BCC?
Morphealike or fibrosing
an indurated yellow plaque with ill-defined borders; overlying skin looks shiny and taut because the tumor causes an intense fibroblastic response that gives this scarlike appearance?
morphelike BCC
where do BCC's arise from?
the basal layer of germinating cells of epithelium or (hair follicles o sebaceous glands)
where do SCC's arise from?
squamous o transitional epithelium esp junction of skin and mucous membrane
what technique is used in the excision of BCC if it is in a difficult location/histology?
Moh's micrographic surgical tech:
6 step process
a kind of skin melanoma. It is also known as subungual melanoma. It is seen on the palms, soles and under the nails. This is the most common form of melanoma in Asians and Blacks.
Acral lentiginous melanoma
what is the standard margin of resection for SCC?
1 cm