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26 Cards in this Set

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What is the fate of a drug: absorption, distribution, inactivation and elimination?
Absorption (Getting drugs into body or blood)
-Distribution (In Blood Stream to carry to site of action)
-In-Activation
-Elimination (Urine through Kidneys)
What are the three tenets of pharmacology? [In Lecture]
All Drugs:
-Effects are dose dependent.
-Have multiple effects.
-Are toxic, but not always deadly.
What are tolerance and withdrawal symptoms and how do they contribute to dependence?
Tolerance: The need for increased amounts of a substance to achieve the desired effects.
Withdrawal: Physical symptoms such as sweating, tremors, and tension that accompany absence of drug. Will keep taking drug to avoid withdrawal symptoms.
What are some other factors that influence the addictive potential of a drug? [In Lecture]
Way of Absorption is directly connected to addictive-ness, because the quicker it leaves the body, the quicker the withdrawal process starts.
*Faster In, Faster Out*
What are designer drugs? How do drugs affect the brain? [In Lecture]
Designer drug is a term used to describe psychoactive drugs which are created to get around existing drug laws.
Effects brain and central nervous system: Sexual activity, memory, reaction time, perception of time and space
Evaluate the success of the use of methadone for the treatment of opiate abuse.
It is used because it satisfies the craving for heroine without producing serious psycho. impairment. Very successful in conjunction with therapy and drug-free environment.
causes and effects of abuse of barbiturates
(sedatives)
Used to calm/relax and induce sleep, but tolerance increases quickly. Can lead to brain damage and personality deterioration, and tolerance can cause fatal overdose.
Withdrawal symptoms are very dangerous.
causes and effects of abuse of amphetamines
(stimulants)-Used to stay alert and heighten functioning. Can result in brain damage, and psychosis, and violence. Withdrawal is safe, but psychological factors are more intense.
causes and effects of abuse of cocaine
Very Popular drug that causes a euphoric state that stimulates cortex of the brain.Tolerance does not increase quickly. Psychological and life problems are biggest effect, including money to support habit.
causes and effects of abuse of LSD
(Hallucinogen) changes in sensory perception, mood swings, and depersonalization and detachment. Can have traumatic effects that are terrifying, called a "Bad trip"
No psycho-dependence, and hospitalization/meds are used for treatment.
Compare the effects of mescaline and psilocybin with those of LSD
(Mushrooms)- Enable a person to transport into a realm of nonordinary reality. Heighten the senses, not as potent as LSD.
Describe the physical and psychological effects of marijuana use and why has it been compared to heroin.
Mild euphoria, increased feeling of well-being, pleasant relaxation, and drifting away. Sense of time is stretched, seconds = hours, loss of short-term memory.
Increased heart rate, bloodshot eyes, increased appetite, tends to diminish self control. Has little in common with heroine, other than similar psychological dependence.
What is the definition of a drug? [In Lecture]
A substance with physiological effects.
What are psychoactive drugs?
a chemical substance that acts primarily upon the central nervous system where it alters brain function, resulting in temporary changes in perception, mood, consciousness and behavior.
What are some pharmacological and nonpharmacological variables that influence an individual’s responses to drugs? [In Lecture]
Can be used as Anesthesia and pain control, and for mental/emotional disorders or recreational use-which have negative effects.
What are the different types of alcoholic psychosis?
Disorientation to time/place, vivid hallucinations, acute fear, extreme suggestibility, tremors of hands/lips, etc perspiration, coated tongue, foul breathe.
Mesocorticolimbic dopamine pathway located in the ventral tegmental area is the reward center active in any drug of abuse.
Mesocorticolimbic dopamine pathway located in the ventral tegmental area is the reward center active in any drug of abuse.
What types of people are most likely to use alcohol and what other disorders accompany alcoholism?
Depression most common.
Schizophrenia, and antisocials are also common. Most alcoholics suffer from at least one pers. disorder.
Describe three major physiological effects of alcohol.
Inhibitions Become Reduced
Loss of Muscle Control
Memory Loss and/or Blackouts
Describe the effects of alcohol on the brain at different doses.
Lower Levels: pleasure areas and causes stimulation of senses
Higher levels: decrease brain function, impair judgment, dull perceptions.
Describe teratogens and alcohol’s effects on a developing fetus
a drug or capable of interfering with the development of a fetus.

A stunt fetal growth, distinctive facial stigmata, damage neurons and brain structures, and cause other physical, mental, or behavioral problems.
What are some physical and interpersonal problems experienced by alcoholics?
Physical: Liver damage, weight gain, stomach pains, and malnutrition.
AND
oversensitivity, depression, inadequacy, neglect of appearance and family.
What are the withdrawal symptoms experienced by alcoholics who try to quit?
Insomnia, headache, gastro problems, tremors, tension, anxiety.
What are the psychosocial and sociological factors that contribute to alcohol-dependence?
Failure in parental guidance, related to antisocial personality and depression, unwilling to to tolerate tension and stress, peer pressure(college binge drinking), marital/relationship crisis periods.
SOCIO-A social lubricant, Some religions forbid it, but the French have highest rate.
Describe the physical and psychosocial effects of morphine and heroin abuse.
Alleviate physical pain, induce relaxation, and relieve anxiety-tension.
Heroine-usually injected-has euphoric rush lasting a minute, similar to an orgasm, followed by a high of relaxation and reverie. A desire for more follows for addicts. The body develops a physical need for drug-which they feel very ill. Has intense withdrawal symptoms. Life will surround finding the drug and maladaptive behavior. Major risk of AIDS.
What are the four major causal factors in the development of opiate-dependence?
1.Neural Bases
endorphins, receptor sites, brain cells
2.Psychopathology Addiction
Antisocial Personality-Heroine, Personality Disorders of all kinds
3.Sociocultural Addiction
Peer pressure, feelings of inadequacy, can't meet demands of adulthood.
4.--